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Pemetrexed

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01BA04

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10
Agranulocytosis 23% - 38% x
Fatigue 0% - 87% 0.6% - 11% x x x x x x x x x x
Leukopenia 0% - 55% 1% x x x x x x x x x
Alopecia 6% - 42% x x x x x x x x
Nausea 0% - 84% 0% - 6% x x x x x x x x x x
Vomiting 0% - 58% 0% - 1.8% x x x x x x x x x x
Creatinine renal clearance decreased 2% - 18% x x x
Dyspnoea 1% - 66% x x x x x x x
Chest pain 1% - 40% x x x x x x x x x x
Dysgeusia 6% x x x x
Neutropenia common, 0% - 58% 0% - 0.6% x x x x x x x x x x
Abdominal pain common x x x x
Anaemia 0% - 33% 0.6% - 6% x x x x x x x x x
Erythema multiforme common x x x
Peripheral sensory neuropathy common x x x x
Creatinine increased common x x x
Peripheral motor neuropathy common x x x x
Diarrhoea 0% - 34% 0% - 3% x x x x x x x x x x
Mucosal inflammation 0.3% - 7% 0% - 2.4% x x x
Embolism 1% - 7% x x x x x x x x
Thrombosis 1% - 7% x x x x x x x x
Anorexia 0% - 62% 0% - 5% x x x x x x x x x x
Myalgia 0% - 20% x x x x
Thrombocytopenia 0% - 27% x x x x x x x x x
Arthralgia 0% - 13% x x x x
Myocardial ischaemia 0% - 3% x x x x
Alanine aminotransferase increased 0% - 10% 0% - 4% x
Infection common, 0% - 11% 0% - 2% x x x x x x x x x x
Constipation 0% - 44% x x x x x x x x x x
Dysphagia 0% - 7% x x x x x x x
Dehydration 0% - 9% x x x x x x x x x x
Oesophagitis 0% - 7% x x x x x x x x x x
Pharyngitis 0% - 28% x x x x x x x x x x
Pruritus 0% - 7% x x x x
Stomatitis 0% - 28% 0% - 2.4% x x x x x x x x x x
Aspartate aminotransferase increased 0% - 8% 0% - 4% x x x x
Odynophagia 0% - 7% x x x x x x x
Neuropathy 0% - 17% 0% - 4% x x x x x x x x x
Febrile neutropenia common, 0% - 9% x x x x x x x x x x
Mood alteration NOS 0% - 14% x x x x x x x
Conjunctivitis 0% - 1% x x x x
Dyspepsia 0% - 1% x x x
Oedema postmarketing, 0% - 24% 0% - 3.6% x x x x x x x x
Rash 0% - 22% 0% - 3% x x x x x x x x x x
Body temperature increased 0% - 26% x x x x x x x x x x
Skin exfoliation 0% - 22% 0% - 3% x x x x x x x x x x
Creatinine low 0% - 5% x x x x x x x
Haemolytic anaemia postmarketing x x x
Colitis postmarketing x x x x x x x
Toxic epidermal necrolysis postmarketing x x x
Pancreatitis postmarketing x
Stevens-Johnson syndrome postmarketing x x x
Interstitial pneumonia postmarketing x x x x
Bullous conditions postmarketing x x x
Anaphylactic shock x
Angina pectoris x
Arrhythmia x x x x
Neoplasm malignant x x x
Transient ischaemic attack x
Dizziness x
Eye disorder x x x
Gastrointestinal disorder x x
Heartburn x x x x
Hepatitis x
Hypersensitivity common, 0% - 2% x x x x x x x x x x
Hypertension x x x x x x x
Intestinal perforation x
Nephropathy x x
Renal failure acute x x
Mesothelioma x x x
Myocardial infarction x
Nervous system disorder x x
Pain x x x x x x x x x
Pancytopenia x
Pulmonary embolism x x
Renal failure 0% - 2% x x x x x x x x x x
Respiratory insufficiency x
Cerebrovascular accident x
Syncope x
Erythema x
Urinary tract disorder x
Urticaria x x x x
Ventricular tachycardia x
Gamma-glutamyltransferase increased x
Lacrimation increased x x x
Haemoglobin decreased x
Malnutrition x x
Unspecified disorder of skin and subcutaneous tissue x x
Radiation pneumonitis x
Peripheral ischaemia x
Gastrointestinal obstruction x
Radiation oesophagitis x
Sepsis x x x x
Caecitis x
Rectal haemorrhage x
Hepatobiliary disease x x
Platelet count decreased x x
Arrhythmia supraventricular x x x x
Metastases to liver x x x x x x x
White blood cell count decreased x
Infestation NOS x
Blood and lymphatic system disorders x x
Glomerular filtration rate decreased x x x
Extremity necrosis x
Ocular surface disease x x x
Intestinal necrosis x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

PEMETREXED DISODIUM / ALIMTA

Side effects:31
Source:FDA

Premetrexed / Alimta

Side effects:31
Source:FDA

PEMETREXED / ALIMTA

Side effects:38
Source:FDA

PEMETREXED DISODIUM / ALIMTA

Side effects:39
Source:FDA

PEMETREXED DISODIUM / ALIMTA

Side effects:39
Source:FDA

PEMETREXED DISODIUM / ALIMTA

Side effects:39
Source:FDA

PEMETREXED (PEMETREXED DISODIUM) / ALIMTA

Side effects:52
Source:Health Canada

Pemetrexed

Side effects:65
Source:FDA Structured Product Label

ALIMTA / Alimta, Powder for infusion

Side effects:61
Source:Medsafe

pemetrexed / pemetrexed

Side effects:86
Source:EMA

Color scheme:

standardalternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label