Oestrogen
Side effects
Options:
Show MedDRA Preferred Terms
Side effect
|
Data for drug
|
Placebo
|
Labels
|
|
1
|
2
|
3
|
4
|
Headache
|
uncommon, 0.575% - 38%
|
28%
|
x
|
x
|
x
|
x
|
Infection
|
0.0576% - 23%
|
22%
|
x
|
x
|
x
|
x
|
Abdominal pain
|
uncommon, 0.716% - 23%
|
11%
|
x
|
x
|
x
|
x
|
Back pain
|
12% - 16%
|
12%
|
|
|
x
|
x
|
Breast pain
|
common, 7% - 38%
|
9%
|
x
|
x
|
x
|
x
|
Pain
|
0.113% - 20%
|
18%
|
|
|
x
|
x
|
Influenza
|
8% - 14%
|
11%
|
|
|
|
x
|
Pharyngitis
|
0.358% - 13%
|
11%
|
|
|
x
|
x
|
Upper respiratory tract infection
|
0.0603% - 13.2%
|
11%
|
|
|
x
|
x
|
Arthralgia
|
common, 1% - 14%
|
12%
|
x
|
x
|
x
|
x
|
Asthenia
|
0.773% - 13.7%
|
5%
|
|
|
x
|
x
|
Dyspepsia
|
5% - 11%
|
14%
|
|
|
x
|
x
|
Sinusitis
|
6% - 11%
|
7%
|
|
|
|
x
|
Endometrial thickening
|
0.15% - 18.9%
|
|
|
|
x
|
|
Nausea
|
uncommon, 0.437% - 11%
|
9%
|
x
|
x
|
x
|
x
|
Flatulence
|
5% - 9%
|
3%
|
|
|
x
|
x
|
Diarrhoea
|
6% - 7%
|
6%
|
|
|
x
|
x
|
Rhinitis
|
1% - 10%
|
13%
|
|
|
x
|
x
|
Accidental injury
|
4% - 12%
|
9%
|
|
|
|
x
|
Insomnia
|
0.484% - 9.8%
|
10%
|
|
|
x
|
x
|
Paraesthesia
|
1% - 7.5%
|
|
|
|
x
|
|
Palpitations
|
1% - 5.9%
|
|
|
|
x
|
|
Vertigo
|
1% - 5.9%
|
|
|
|
x
|
|
Cough increased
|
4% - 8%
|
4%
|
|
|
x
|
x
|
Alopecia
|
common
|
|
x
|
x
|
|
|
Vaginal moniliasis
|
uncommon, 4% - 8%
|
2%
|
x
|
x
|
x
|
x
|
Cramps of lower extremities
|
common, 3% - 7%
|
2%
|
x
|
x
|
x
|
x
|
Leukorrhea
|
common, 3% - 9%
|
3%
|
x
|
x
|
|
x
|
Uterine haemorrhage
|
common
|
|
x
|
x
|
|
|
Myalgia
|
0.157% - 11.8%
|
8%
|
|
|
x
|
x
|
Tenderness
|
common
|
|
x
|
x
|
x
|
x
|
Cervix disorder
|
4% - 5%
|
|
|
|
|
x
|
Dizziness
|
uncommon, 3% - 6%
|
5%
|
x
|
x
|
x
|
x
|
Dysmenorrhoea
|
rare, 1% - 13%
|
1%
|
x
|
x
|
x
|
x
|
Pruritus
|
uncommon, 4% - 5%
|
2%
|
x
|
x
|
x
|
x
|
Anxiety
|
0.618% - 5.7%
|
4%
|
|
|
x
|
x
|
Weight increased
|
1% - 5.7%
|
|
|
|
x
|
|
Depression
|
0.0895% - 13.7%
|
|
|
|
x
|
x
|
Rash
|
uncommon, 3% - 6%
|
|
x
|
x
|
x
|
x
|
Hypertonia
|
3% - 7%
|
|
|
|
x
|
x
|
Vaginal haemorrhage
|
1% - 14%
|
0%
|
|
|
x
|
x
|
Nervousness
|
uncommon, 0.0895% - 13.7%
|
|
x
|
x
|
x
|
x
|
Breast enlargement
|
1% - 5%
|
1%
|
|
|
|
x
|
Vaginal inflammation
|
uncommon, 0.363% - 7.5%
|
|
x
|
x
|
x
|
x
|
Oedema
|
uncommon
|
|
x
|
x
|
x
|
x
|
Hirsutism
|
uncommon
|
|
x
|
x
|
x
|
x
|
Hypersensitivity
|
uncommon
|
|
x
|
x
|
|
|
Chloasma
|
uncommon
|
|
x
|
x
|
x
|
x
|
Pulmonary embolism
|
uncommon
|
|
x
|
x
|
x
|
x
|
Venous thrombosis
|
uncommon
|
|
x
|
x
|
|
|
Migraine
|
uncommon
|
|
x
|
x
|
x
|
x
|
Ectropion of cervix
|
uncommon
|
|
x
|
x
|
x
|
|
Dementia
|
uncommon
|
|
x
|
x
|
x
|
|
Abdominal bloating
|
uncommon
|
|
x
|
x
|
x
|
x
|
Mood alteration NOS
|
uncommon
|
|
x
|
x
|
x
|
x
|
Gallbladder disorder
|
rare, uncommon
|
|
x
|
x
|
x
|
x
|
Angioedema
|
rare
|
|
x
|
x
|
x
|
x
|
Breast cancer
|
rare
|
|
x
|
x
|
x
|
x
|
Epilepsy
|
rare
|
|
x
|
x
|
x
|
x
|
Fibrocystic breast disease
|
rare
|
|
x
|
x
|
x
|
x
|
Irritability
|
rare
|
|
x
|
x
|
x
|
x
|
Myocardial infarction
|
rare
|
|
x
|
x
|
x
|
x
|
Pancreatitis
|
rare
|
|
x
|
x
|
x
|
x
|
Pelvic pain
|
rare
|
|
x
|
x
|
|
x
|
Cerebrovascular accident
|
rare
|
|
x
|
x
|
x
|
x
|
Urticaria
|
rare
|
|
x
|
x
|
x
|
x
|
Uterine leiomyoma
|
rare
|
|
x
|
x
|
x
|
x
|
Vomiting
|
rare
|
|
x
|
x
|
x
|
x
|
Colitis ischaemic
|
rare
|
|
x
|
x
|
|
|
Galactorrhoea
|
rare
|
|
x
|
x
|
x
|
x
|
Glucose tolerance impaired
|
rare
|
|
x
|
x
|
|
|
Meningioma benign
|
rare
|
|
x
|
x
|
|
|
Anaphylactoid reaction
|
rare
|
|
x
|
x
|
|
|
Exacerbation of asthma
|
rare
|
|
x
|
x
|
x
|
x
|
Ovarian cancer
|
rare
|
|
x
|
x
|
x
|
x
|
Thrombophlebitis superficial
|
rare
|
|
x
|
x
|
|
|
Chorea
|
very rare
|
|
x
|
x
|
x
|
x
|
Endometrial hyperplasia
|
very rare
|
|
x
|
x
|
x
|
x
|
Erythema multiforme
|
very rare
|
|
x
|
x
|
x
|
x
|
Erythema nodosum
|
very rare
|
|
x
|
x
|
x
|
x
|
Haemangioma
|
very rare
|
|
x
|
x
|
x
|
x
|
Hypocalcaemia
|
very rare
|
|
x
|
x
|
x
|
x
|
Jaundice cholestatic
|
very rare
|
|
x
|
x
|
x
|
x
|
Porphyrin metabolism disorder
|
very rare
|
|
x
|
x
|
x
|
x
|
Endometrial cancer
|
very rare
|
|
x
|
x
|
x
|
x
|
Blood pressure increased
|
very rare
|
|
x
|
x
|
x
|
x
|
Retinal vascular thrombosis
|
very rare
|
|
x
|
x
|
x
|
x
|
Abdominal cramps
|
|
|
|
|
x
|
x
|
Amenorrhoea
|
|
|
|
|
|
x
|
Anaphylactic shock
|
|
|
|
|
x
|
x
|
Mental disorder
|
|
|
x
|
x
|
|
|
Bone disorder
|
|
|
x
|
x
|
|
|
Breast disorder
|
|
|
x
|
x
|
|
|
Uterine cervical erosion
|
|
|
|
|
|
x
|
Constipation
|
|
|
|
|
x
|
|
Cyst
|
|
|
x
|
x
|
|
|
Eye disorder
|
|
|
x
|
x
|
|
|
Fatigue
|
|
|
|
|
|
x
|
Body temperature increased
|
|
|
|
|
x
|
x
|
Gastrointestinal disorder
|
|
|
x
|
x
|
|
|
Cardiac disorder
|
|
|
x
|
x
|
|
|
Immune system disorder
|
|
|
x
|
x
|
|
|
Mediastinal disorder
|
|
|
x
|
x
|
|
|
Metrorrhagia
|
|
|
|
|
x
|
x
|
Neoplasm
|
|
|
x
|
x
|
|
|
Nervous system disorder
|
|
|
x
|
x
|
|
|
Optic neuritis
|
|
|
|
|
|
x
|
Polyp
|
|
|
x
|
x
|
|
|
Thrombophlebitis
|
|
|
|
|
x
|
x
|
Angiopathy
|
|
|
x
|
x
|
|
|
Oedema peripheral
|
|
|
|
|
x
|
x
|
Breast discharge
|
|
|
|
|
x
|
x
|
Malnutrition
|
|
|
x
|
x
|
|
|
Unspecified disorder of skin and subcutaneous tissue
|
|
|
x
|
x
|
|
|
Superficial phlebothrombosis
|
|
|
|
|
x
|
x
|
Dermatitis hemorrhagic
|
|
|
|
|
x
|
x
|
Hepatobiliary disease
|
|
|
x
|
x
|
|
|
Rash generalised
|
|
|
|
|
|
x
|
Infestation NOS
|
|
|
x
|
x
|
|
|
Abnormal withdrawal bleeding
|
|
|
|
|
x
|
x
|
Somnolence
|
|
|
|
|
|
x
|
Bleeding breakthrough
|
|
|
|
|
x
|
x
|
Indications
Information about indications was extracted from the indications and usage sections of the labels.
Side effects: | 78 |
Source: | medicines.org.au |
---|
Side effects: | 78 |
Source: | Medsafe |
---|
Side effects: | 83 |
Source: | FDA Structured Product Label |
---|
Side effects: | 88 |
Source: | FDA |
---|
Color scheme:
standard – alternative
|
|
100%
|
|
|
75%
|
|
|
50%
|
|
|
10%
|
|
|
frequent (1% to 100%)
|
|
|
infrequent (0.1% to 1%)
|
|
|
rare (<0.1%)
|
|
|
postmarketing
|
|
|
0%
|
|
|
no frequency information
|
|
|
not found on label
|