Idiopathic thrombocytopenic purpura
Definition: Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.
Synonyms (terms occurring on more labels are shown first): idiopathic thrombocytopenic purpura, idiopathic thrombocytopenia purpura
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