Acetaminophen
Side effects
Options:
Show MedDRA Preferred Terms
Side effect
|
Data for drug
|
Placebo
|
Labels
|
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
|
10
|
11
|
12
|
13
|
14
|
15
|
16
|
17
|
Injection site pain
|
2% - 14.7%
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Nervous system disorder
|
very rare, 9.7%
|
8.71%
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
Injection site reaction
|
2.67% - 14.7%
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Mental disorder
|
7.46%
|
5.54%
|
|
|
|
|
x
|
|
|
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
Insomnia
|
7.46%
|
1.96% - 5.54%
|
|
|
|
|
x
|
x
|
x
|
x
|
|
x
|
|
|
|
|
x
|
x
|
x
|
Constipation
|
6.7%
|
11.8%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
x
|
|
x
|
x
|
Headache
|
1.3% - 9.7%
|
4.9% - 8.71%
|
|
|
|
|
x
|
|
|
x
|
|
|
|
|
|
|
|
|
|
Drowsiness
|
common
|
|
|
|
|
x
|
|
|
|
|
x
|
|
|
|
|
x
|
|
x
|
|
Dry mouth
|
common
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
x
|
|
|
x
|
Disturbance in attention
|
common
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
x
|
Unsteadiness
|
common
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
Vomiting
|
postmarketing, 4% - 5.26%
|
2.9%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
x
|
x
|
Anaemia
|
2.7%
|
6.9%
|
|
x
|
|
|
x
|
x
|
|
x
|
|
|
|
|
|
|
|
|
|
Dizziness
|
common, 2.7%
|
2.9%
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
x
|
x
|
x
|
x
|
Cough
|
2%
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Postoperative hemorrhage
|
2%
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
Enlargement abdomen
|
2%
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Fatigue
|
common, 1.59%
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
x
|
x
|
Chest pain
|
1.33%
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Diarrhoea
|
1.3%
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
x
|
Dyspepsia
|
1.3%
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
Hyperglycaemia
|
1.3%
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Hypokalaemia
|
1.3%
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Alveolitis
|
1.3%
|
2.94%
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Body temperature increased
|
1.05% - 5.47%
|
5.9% - 13.7%
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Hypotonia
|
1.05%
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Nausea
|
postmarketing, 1.05% - 10%
|
8.8%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
Gastrointestinal disorder
|
postmarketing — 2%
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
Anaphylactic shock
|
postmarketing
|
|
|
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Bladder neck obstruction
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Dermatitis atopic
|
postmarketing
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Dysuria
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Oedema
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Rash
|
postmarketing
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Eye disorder
|
postmarketing — common
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Flushing
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Angle closure glaucoma
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Cardiac disorder
|
postmarketing, rare
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
x
|
Hypersensitivity
|
postmarketing
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
x
|
Mydriasis
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Palpitations
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
x
|
x
|
x
|
Pruritus
|
postmarketing, 3.3%
|
4.9%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Tachycardia
|
postmarketing
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
x
|
x
|
x
|
Thrombocytopenia
|
postmarketing
|
|
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Erythema
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Urinary tract disorder
|
postmarketing, rare
|
|
|
|
|
|
x
|
|
|
|
x
|
|
|
|
|
|
x
|
x
|
x
|
Urticaria
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
x
|
Urinary retention
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
x
|
x
|
x
|
Hepatic failure
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Hepatic necrosis
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Acute angle-closure glaucoma
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Unspecified disorder of skin and subcutaneous tissue
|
postmarketing
|
|
x
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Hepatic enzyme increased
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Hepatitis fulminant
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Administration site reaction
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Prostatic hypertrophy
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Immune system disorder
|
very rare, postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Mediastinal disorder
|
very rare
|
|
|
|
|
|
x
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Hepatobiliary disease
|
very rare, postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Blood and lymphatic system disorders
|
very rare
|
|
|
|
|
|
x
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Abdominal pain
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
x
|
Pancreatitis acute
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
Agranulocytosis
|
|
|
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Haemolytic anaemia
|
|
|
|
|
x
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
Angioedema
|
|
|
x
|
|
x
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
x
|
x
|
x
|
Anorexia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Anxiety
|
|
|
|
|
|
|
x
|
|
|
|
|
x
|
|
|
|
|
|
x
|
x
|
Asthma
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Atelectasis
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
Bronchospasm
|
|
|
|
|
x
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Coma
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Confusional state
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
x
|
Connective tissue disorder
|
|
|
|
|
|
|
x
|
|
|
|
x
|
|
|
|
|
|
|
|
x
|
Dermatitis exfoliative
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Dyskinesia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Dyspnoea
|
|
|
|
|
x
|
x
|
x
|
|
|
|
x
|
|
|
|
|
|
|
|
|
Toxic epidermal necrolysis
|
|
|
|
|
x
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Eructation
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Hallucination
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Blood disorder
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
Haemorrhage
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
Hypertension
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Hypotension
|
|
|
|
|
x
|
|
x
|
|
x
|
x
|
|
|
|
|
|
|
|
|
x
|
Irritability
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
x
|
Renal failure acute
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Nephrosis lower nephron
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Leukopenia
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Myoclonus
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Nervousness
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
Neutropenia
|
|
|
|
x
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Nightmare
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Oliguria
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
Pain in extremity
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
Pancytopenia
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Pleural effusion
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
Pulmonary oedema
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
Convulsion
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
Shivering
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Shock
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Muscle spasms
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
Stevens-Johnson syndrome
|
|
|
|
|
x
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Stridor
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
Sweating
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Tremor
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Trismus
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
Uremia
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Angiopathy
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Wheezing
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
Agitation
|
|
|
|
|
|
|
x
|
|
|
|
x
|
x
|
|
|
|
|
|
x
|
x
|
Rash pustular
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Oedema peripheral
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Hypophosphataemia
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
Hepatic function abnormal
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Periorbital oedema
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
Hypomagnesaemia
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
Hepatocellular injury
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Muscular weakness
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Hyperreflexia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Aspartate aminotransferase increased
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
Urinary hesitation
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Liver injury
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
Malnutrition
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Acute hepatic failure
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Lightheadedness
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Rash macular
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Fixed drug eruption
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Malaise
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Muscle twitching
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
x
|
Breath sounds abnormal
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
Chest tightness
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
x
|
Digestion impaired
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
x
|
|
Abdominal discomfort
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Dysphoria
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Respiratory depression
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Euphoric mood
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Pemphigoid reaction
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Hypoalbuminaemia
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
Strangury
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
Vision blurred
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
x
|
Photosensitivity
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Rash maculo-papular
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Energy increased
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
x
|
Blood pressure increased
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Coordination abnormal
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Dystonic reaction
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
Fluid overload
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
Cutaneous hypersensitivity
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Drug interaction
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Serotonin syndrome
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Sweating increased
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Mental status changes
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Acute generalised exanthematous pustulosis
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Anaemia postoperative
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
Cytolytic hepatitis
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Infusion site pain
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
Kounis syndrome
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Somnolence
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Indications
Information about indications was extracted from the indications and usage sections of the labels.
Side effects: | 5 |
Source: | Medsafe |
---|
Side effects: | 9 |
Source: | medicines.org.au |
---|
Side effects: | 24 |
Source: | medicines.org.au |
---|
Side effects: | 16 |
Source: | FDA Structured Product Label |
---|
Side effects: | 51 |
Source: | FDA Structured Product Label |
---|
Side effects: | 43 |
Source: | medicines.org.au |
---|
Side effects: | 56 |
Source: | Medsafe |
---|
Side effects: | 58 |
Source: | medicines.org.au |
---|
Side effects: | 39 |
Source: | Medsafe |
---|
Side effects: | 18 |
Source: | medicines.org.au |
---|
Side effects: | 12 |
Source: | medicines.org.au |
---|
Side effects: | 12 |
Source: | medicines.org.au |
---|
Side effects: | 12 |
Source: | medicines.org.au |
---|
Side effects: | 21 |
Source: | medicines.org.au |
---|
Side effects: | 36 |
Source: | Medsafe |
---|
Side effects: | 52 |
Source: | medicines.org.au |
---|
Side effects: | 64 |
Source: | medicines.org.au |
---|
Color scheme:
standard – alternative
|
|
100%
|
|
|
75%
|
|
|
50%
|
|
|
10%
|
|
|
frequent (1% to 100%)
|
|
|
infrequent (0.1% to 1%)
|
|
|
rare (<0.1%)
|
|
|
postmarketing
|
|
|
0%
|
|
|
no frequency information
|
|
|
not found on label
|