Search results :

Ponatinib

More information: STITCH, PubChem and possibly Wikipedia

ATC Codes: None found

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2
Neutropenia 13% - 63% x x
Hypertension 26% - 71% x
Platelet count decreased 2.9% - 47% x x
Thrombocytopenia 4% - 47% x x
Leukopenia 12% - 63% x x
White blood cell count decreased 12% - 63% x x
Calcium low 1% - 52% x
Anaemia 9% - 55% x x
Lymphopenia 9% - 37% x x
Asthenia 3% - 39% x x
Fatigue 3% - 39% x x
Albumin low 1% - 28% x
Headache 0% - 39% x x
Constipation 0% - 47% x x
Dry skin 0% - 39% x x
Nausea 0% - 32% x x
Glucose decreased 0% - 24% x
Rash 5% - 54% x x
Abdominal pain 3.6% - 49% x x
Lipase increased 1.3% - 41% x x
Blood bilirubin increased 1% - 19% x x
Ischaemia 0% - 20% x
Pneumonia 2% - 13% x x
Alanine aminotransferase increased 6% - 53% x x
Phosphorus low 6% - 57% x x
Arthralgia 0% - 31% x x
Vomiting 0% - 24% x x
Oedema 0% - 22% x
Back pain 0% - 16% x x
Dyspnoea 0% - 21% x x
Sepsis 1% - 22% x x
Cardiac failure 3% - 15% x x
Gamma-glutamyltransferase increased 6% x x
Bone pain 1% - 12% x x
Mucosal inflammation 0% - 23% x
Glucose increased 0% - 58% x x
Pancreatitis 5.1% - 6% x x
Gastrointestinal haemorrhage 1% - 11% x
Pain in extremity 0% - 17% x x
Sodium high 1% - 10% x
Body temperature increased 0% - 32% x x
Chills 0% - 13% x x
Pain 0% - 16% x x
Decreased appetite 0% - 31% x x
Sodium decreased 2% - 29% x x
Neuropathy peripheral 0% - 16% x x
Febrile neutropenia 1% - 25% x x
Creatinine increased 1% - 7% x
Insomnia 0% - 12% x x
Myalgia 0% - 22% x x
Cough 0% - 18% x x
Diarrhoea 0% - 26% x x
Pleural effusion 0% - 19% x x
Aspartate aminotransferase increased 2% - 41% x x
Myocardial infarction 2.9% x
Weight decreased 0% - 13% x x
Muscle spasms 0% - 13% x x
Ca++ increased 0% - 5% x
Cellulitis 0% - 11% x
Phosphatase alkaline increased 1% - 37% x x
Potassium increased 1% - 15% x x
Potassium low 1% - 16% x x
Amylase increased 1% - 3% x
Dizziness 0% - 11% x x
Nasopharyngitis 0% - 12% x
Upper respiratory tract infection 0% - 11% x x
Pancytopenia 1.3% x
Neutrophil count decreased 1.3% x
Infection 1% x x
Urinary tract infection 0% - 12% x
Amylase decreased 0% - 2% x
Abdominal distension x
Alopecia x
Angina pectoris x
Prinzmetal angina x
Arrhythmia x
Atrial fibrillation x x
Atrial flutter x
Mental disorder x x
Breast disorder x
Neoplasm malignant x
Cardiovascular disorder x
Cerebral infarction x
Neck pain x
Connective tissue disorder x x
Dehydration x
Dermatitis exfoliative x
Dyspepsia x
Ecchymosis x
Effusion x
Epistaxis x
Eye disorder x
Flushing x
Folliculitis x
Gastrooesophageal reflux disease x
Gastrointestinal disorder x x
Cardiac disorder x
Cardiac failure congestive x
Haemorrhage x
Hyperaesthesia x
Hyperglycaemia x
Hyperhidrosis x
Hypertriglyceridaemia x
Hypoaesthesia x
Hypocalcaemia x
Hypokalaemia x
Intermittent claudication x
Jaundice x
Lethargy x
Mediastinal disorder x x
Musculoskeletal pain x
Nervous system disorder x x
Night sweats x
Paraesthesia x
Pericardial effusion x
Petechiae x
Prurigo x
Pruritus x
Pulmonary embolism x
Retinal vein occlusion x
Splenic infarction x
Stomatitis x
Cerebrovascular accident x
Tumour lysis syndrome x
Erythema x
Angiopathy x x
Venous thrombosis x
Dry mouth x
Oedema peripheral x
Hypophosphataemia x
Deep vein thrombosis x
Migraine x
Periorbital oedema x
Myocardial ischaemia x
Eyelid oedema x
Malnutrition x x
Unspecified disorder of skin and subcutaneous tissue x x
Abdominal discomfort x
Gastric haemorrhage x
Hepatotoxicity x x
Peripheral ischaemia x
Skin exfoliation x
Pain of skin x
Erectile dysfunction x
Left ventricular dysfunction x
Hepatobiliary disease x
Fluid retention x x
Dry eye x
Embolism venous x
Vision blurred x
Ischaemic cardiomyopathy x
Neuropathy x
Musculoskeletal chest pain x
Non-cardiac chest pain x
Poor peripheral circulation x
Influenza like illness x
Face oedema x
Hot flush x
Hyperuricaemia x
Ejection fraction decreased x
Infestation NOS x x
Blood and lymphatic system disorders x x
Blood alkaline phosphatase increased x
Blood amylase increased x
Myelosuppression x x
Acute coronary syndrome x
Cardiac discomfort x
Vascular occlusion x x
Ocular toxicity x
Peripheral arterial occlusive disease x
Cerebral artery stenosis x
Dysphonia x
Retinal vein thrombosis x
Exfoliative rash x
Venous thromboembolism x
Coronary artery disease x
Peripheral artery stenosis x
Visual impairment x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

ponatinib

Side effects:89
Source:FDA Structured Product Label

ponatinib / ponatinib

Side effects:156
Source:EMA

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label