Guanfacine
Side effects
Options:
Show MedDRA Preferred Terms
Side effect
|
Data for drug
|
Placebo
|
Labels
|
|
1
|
2
|
3
|
4
|
Dry mouth
|
postmarketing, 2% - 60%
|
0% - 6.85%
|
x
|
x
|
x
|
x
|
Somnolence
|
postmarketing, 18% - 38%
|
1.37% - 12%
|
x
|
x
|
x
|
x
|
Drowsiness
|
6% - 33%
|
|
|
x
|
x
|
x
|
Dizziness
|
postmarketing, 1% - 15%
|
2.74% - 8%
|
x
|
x
|
x
|
x
|
Fatigue
|
postmarketing, 2% - 14%
|
2% - 4.11%
|
x
|
x
|
x
|
x
|
Decreased appetite
|
5% - 7%
|
3% - 4%
|
x
|
|
|
|
Irritability
|
6%
|
4%
|
x
|
|
|
|
Lethargy
|
6%
|
3%
|
x
|
|
|
|
Constipation
|
postmarketing, 2% - 14%
|
0% - 1%
|
x
|
x
|
x
|
x
|
Headache
|
postmarketing, 0.2% - 24%
|
4.11% - 19%
|
x
|
x
|
x
|
x
|
Hypotension
|
3% - 7%
|
0% - 3%
|
x
|
|
|
|
Insomnia
|
postmarketing, 0% - 12%
|
6%
|
x
|
x
|
x
|
x
|
Affect lability
|
2%
|
1%
|
x
|
|
|
|
Asthenia
|
postmarketing, 1% - 5%
|
0%
|
x
|
x
|
x
|
x
|
Abdominal pain
|
postmarketing, 10% - 11%
|
3% - 9%
|
x
|
x
|
x
|
x
|
Alopecia
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Anxiety
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Arthralgia
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Chest pain
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Confusional state
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Dermatitis
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Dermatitis exfoliative
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Diarrhoea
|
postmarketing, 4%
|
1%
|
x
|
x
|
x
|
x
|
Dysgeusia
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Dyspepsia
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Dyspnoea
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Oedema
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Rash
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Eye disorder
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Hallucination
|
postmarketing
|
|
x
|
|
|
|
Block heart
|
postmarketing
|
|
|
x
|
x
|
x
|
Cardiac failure congestive
|
postmarketing
|
|
|
x
|
x
|
x
|
Renal failure acute
|
postmarketing
|
|
|
x
|
x
|
x
|
Cramps of lower extremities
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Leg pain
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Myocardial infarction
|
postmarketing
|
|
|
x
|
x
|
x
|
Nausea
|
postmarketing, 5% - 6%
|
2% - 3%
|
x
|
x
|
x
|
x
|
Nervousness
|
postmarketing
|
|
|
x
|
x
|
x
|
Nocturia
|
postmarketing
|
|
|
x
|
x
|
x
|
Palpitations
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Paraesthesia
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Pruritus
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Cerebrovascular accident
|
postmarketing
|
|
|
x
|
x
|
x
|
Syncope
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Tachycardia
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Tremor
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Pollakiuria
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Vertigo
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Agitation
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Liver function test abnormal
|
postmarketing
|
|
|
x
|
x
|
x
|
Malaise
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Myalgia
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Cardiac fibrillation
|
postmarketing
|
|
|
x
|
x
|
x
|
Erectile dysfunction
|
postmarketing
|
0% - 1.37%
|
x
|
x
|
x
|
x
|
Vision blurred
|
postmarketing
|
|
x
|
x
|
x
|
x
|
Bradycardia
|
postmarketing, 2%
|
0%
|
x
|
x
|
x
|
x
|
Amnesia
|
|
|
|
x
|
x
|
x
|
Sinus arrhythmia
|
|
|
x
|
|
|
|
Asthma
|
|
|
x
|
|
|
|
Atrioventricular block
|
|
|
x
|
|
|
|
Conjunctivitis
|
|
|
|
x
|
x
|
x
|
Dysphagia
|
|
|
|
x
|
x
|
x
|
Enuresis
|
|
|
x
|
|
|
|
Hypersensitivity
|
|
|
x
|
|
|
|
Orthostatic hypotension
|
|
|
x
|
x
|
x
|
x
|
Immune system disorder
|
|
|
x
|
|
|
|
Iritis
|
|
|
|
x
|
x
|
x
|
Nightmare
|
|
|
x
|
x
|
x
|
x
|
Pallor
|
|
|
x
|
|
|
|
Paresis
|
|
|
|
x
|
x
|
x
|
Purpura
|
|
|
|
x
|
x
|
x
|
Rhinitis
|
|
|
|
x
|
x
|
x
|
Convulsion
|
|
|
x
|
|
|
|
Sweating
|
|
|
|
x
|
x
|
x
|
Testicular disorder
|
|
|
|
x
|
x
|
x
|
Tinnitus
|
|
|
|
x
|
x
|
x
|
Urinary incontinence
|
|
|
|
x
|
x
|
x
|
Vomiting
|
|
|
x
|
|
|
|
Weight increased
|
|
|
x
|
|
|
|
Hypokinesia
|
|
|
|
x
|
x
|
x
|
Retrosternal pain
|
|
|
|
x
|
x
|
x
|
Alanine aminotransferase increased
|
|
|
x
|
|
|
|
Abdominal pain upper
|
|
|
x
|
|
|
|
Abdominal pain lower
|
|
|
x
|
|
|
|
Upset stomach
|
|
|
x
|
|
|
|
Skin exfoliation
|
|
|
|
x
|
x
|
x
|
Initial insomnia
|
|
|
x
|
|
|
|
Middle insomnia
|
|
|
x
|
|
|
|
Hypertensive
|
|
|
|
x
|
x
|
x
|
Hypersomnia
|
|
|
x
|
|
|
|
Loss of libido
|
|
|
|
x
|
x
|
x
|
Visual impairment
|
|
|
|
x
|
x
|
x
|
Indications
Information about indications was extracted from the indications and usage sections of the labels.
Side effects: | 65 |
Source: | FDA Structured Product Label |
---|
Side effects: | 69 |
Source: | FDA Structured Product Label |
---|
Side effects: | 69 |
Source: | FDA Structured Product Label |
---|
Side effects: | 69 |
Source: | FDA Structured Product Label |
---|
Color scheme:
standard – alternative
|
|
100%
|
|
|
75%
|
|
|
50%
|
|
|
10%
|
|
|
frequent (1% to 100%)
|
|
|
infrequent (0.1% to 1%)
|
|
|
rare (<0.1%)
|
|
|
postmarketing
|
|
|
0%
|
|
|
no frequency information
|
|
|
not found on label
|