Search results :

Methotrexate

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Codes: L01BA01, L04AX03

Side effects

Options: Show MedDRA Preferred Terms,   display all 24 labels

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Alopecia 1-10% x x x x x x x x x x x x x x x x x x x x
Diabetes mellitus 1-10% x x x x x x x x x x x x x x x x x x x
Dizziness 1-10% x x x x x x x x x x x x x x x x x x x
Rash 1-10% x x x x x x x x x x x x x x x x x x x x
Convulsion 1-10% x x x x x x x x x x x x x x x x x x x x
Vasculitis 1-10% x x x x x x x x x x x x x x x x x x x x
Malaise 1-10% x x x x x x x x x x x x x x x x x x x
Myalgia 1-10% x x x x x x x x x x x x x x x x x x x x
Vision blurred 1-10% x x x x x x x x x x x x x x x x x x x
Photosensitivity 1-10% x x x x x x x x x x x x x x x x x x x
Pulmonary toxicity 2-8% x x x x x x x
Anaphylactic shock 1% x x x x x x
Abdominal pain x
Abscess x
Agranulocytosis x x x x x x x x x x
Alveolitis allergic x
Anaemia x x x x x x x x x x x x x x x x x x x
Aplastic anaemia x x x x x x x x x x x x x x x x x
Anaemia megaloblastic x x x x x x
Anorexia x x x x x x x x x x x x x x x x x x x
Anuria x
Aphasia x x x x x x x x x x x x x x x x x x
Apnoea x
Arachnoiditis x x x x x
Arthralgia x x x x x x x x x x x x x x x x x x x x
Asthenia x
Asthma x
Ataxia x x x x
Back pain x x x x
Bacterial infection x
Mental disorder x
Bone disorder x x
Breast disorder x
Burkitt's lymphoma x
Cardiac tamponade x
Chest pain x x x x x x x x x x x x x x x x x
Coma x x x x x x
Infection x x x x x x x x x x x x x x x x x x x
Confusional state x x x x x x x
Conjunctivitis x x x x x x x x x x x x x x x x
Cough x x x x x x x x x x x x x x x x x
Cryptococcosis x x x x x x x x x x x x x x x x x
Cyanosis x
Cystitis x x x x x x x x x x x x x x x x x x
Cyst x
Cytomegalovirus infection x x x x
Sudden death x x x x x x x x x x x x x x x x x x x
Depression x
Dermatitis x x x x x x x x x x x x x x x x x x x
Dermatitis exfoliative x x x x x x x x x x x x x x x x x x x
Diarrhoea x x x x x x x x x x x x x x x x x x x x
Drowsiness x x x x x x x x x x x x x x x x x x x
Dysarthria x x x x x x x x x x x x x x
Dyspepsia x
Dyspnoea x x x x x x x
Dysuria x x x x x x x x x x x x x x x x x x
Ecchymosis x x x x x x x x x x x x x x x x x x x x
Enteritis x x x x x x x x x x x x x x x x x x x
Eosinophilia x x x x x x x x x x
Toxic epidermal necrolysis x x x x x x x x x x x x x x x x x x x
Epistaxis x x x x x x x x x x
Erythema multiforme x x x x x x x x x x x x x x x x x x x x
Extravasation x
Eye disorder x x
Fatigue x x x x x x x x x x x x x x x x x x x x
Foetal death x x x x x x x x x
Body temperature increased x x x x x x x x x x x x x x x x x x x x
Fibrosis x x x x x x x x x x x x x x x x x x
Folliculitis x x x x x x
Fracture x
Stress fracture x x x x x x x x x x x x x x x x x
Furunculosis x x x x x x x x x x x x x x x x x x x x
Gastrointestinal disorder x
Gingivitis x x x x x x x x x x x x x x x x x x x x
Glossitis x x x x x x
Guillain-Barre syndrome x x
Gynaecomastia x x x x x x x x x x x x x x x x
Headache x x x x x x x x x x x x x x x x x x x x
Cardiac disorder x
Haematemesis x x x x x x x x x x x x x x x x x x x x
Haematuria x x x x x x x x x x x x x x x x x x x x
Hemiparesis x x x x x x x x x x x x x x x x x x x
Haemorrhage x x x x x x x
Hepatitis x x x x x x x x x x x x x x x x
Chronic hepatitis x
Herpes simplex x x x
Herpes zoster x x x x x x x x x x x x x x x x x x
Histoplasmosis x x x x x x x x x x x x x x x x x
Hyperbilirubinaemia x
Hypersensitivity x x x x x
Hypotension x x x x x x x x x x x x x x x x x x x x
Immunodeficiency x
Immune system disorder x
Infertility x x x x x x x x x x x x x x x x x x x
Inflammation x
Intestinal perforation x x x x x
Irritability x x x x
Nephropathy x x x x x x x x x x x x x x x x x x
Renal failure acute x
Lethargy x x x x
Leukaemia x
Leukopenia x x x x x x x x x x x x x x x x x x
Hepatic cirrhosis x x x x x x
Lung disorder x x
Chronic obstructive pulmonary disease x
Lymphoproliferative disorder x x x x x x x x x x x
Malabsorption x x x x x x
Mediastinal disorder x
Megacolon toxic x x x x x x
Melaena x x x x x x x x x x x x x x x x x x x
Meningism x
Meningitis aseptic x x
Fungal infection x
Nausea x x x x x x x x x x x x x x x x x x x x
Necrosis x x x x x
Neoplasm x x
Nervous system disorder x
Neutropenia x x x x x x x x x x x x x x
Nocardiosis x x x x x x x x x x x x x x x x x x
Nodule x
Oligospermia x x x x x x x x x x x x x x x x x x x
Oliguria x
Opportunistic infection x x x x x x x x x x x x x x x x x x x
Osteonecrosis x x x x x x x x x x x x x x x
Osteoporosis x x x x x x x x x x x x x x x
Pain x x
Pancreatitis x x x x x x x x x x x x x x x x x x x
Pancytopenia x x x x x x x x x x x x x x x x x x
Paraplegia x x x
Paresis x x x x x x x x x x x x x x x x
Paronychia x
Pericardial effusion x x x x x x x x x x x x x x x x x x x x
Pericarditis x x x x x x x x x x x x x x x x x x x x
Petechiae x x x x x x x
Pharyngitis x x x x x x x x x x x x x x x x x x x x
Pleural effusion x x
Pleurisy x
Pneumonia x x x x x x x x x x x x x x x x
Polyp x
Polyuria x
Proteinuria x x x x x x x x x x
Pruritus x x x x x x x x x x x x x x x x x x x x
Pulmonary oedema x
Pulmonary embolism x x x x x x x x x x x x x x x x x x x x
Pulmonary fibrosis x x
Dermatitis radiation NOS x x x x x
Rales x
Renal failure x x x x x x x x x x x x x x x x x x x
Retinal disorder x
Septicemia x x x x x
Skin ulcer x x x x x x x x x x x x x x x
Spinal cord disorder x
Stevens-Johnson syndrome x x x x x x x x x x x x x x x x x x x x
Stomatitis x x x x x x x x x x x x x x x x x x x x
Ulcerative stomatitis x x x x x x x x x x x x x x x x x
Cerebrovascular accident x
Sunburn x x x x x
Sweating x x x x x x x x x x x
Telangiectasia x x x x x x x x x x x x x x x x x x x x
Thrombocytopenia x x x x x x x x x x x x x x x x x
Thrombophlebitis x x x x x x x x x x x x x x x x x x
Tinnitus x x x x x x x x x x x x x x x x x
Tumour lysis syndrome x x x x x x x x x x x x x x x x x x
Ulcer x x x x x x
Erythema x x x x x x
Upper respiratory tract infection x x x x x x x x x x x
Ureteric obstruction x
Urinary tract disorder x
Urticaria x x x x x x x x x x x x x x x x x x x
Vaginal inflammation x x x x x
Angiopathy x
Vertigo x
Vomiting x x x x x x x x x x x x x x x x x x x x
Cerebral thrombosis x x x x x x x x x x x x x x x x x x x x
Hidradenitis x
Encephalopathy x x x x x x x x x x x x x x x x x x x
Chills x x x x x x x x x x x x x x x x x x x
Hepatic failure x x x x x x x x x
Burning sensation x
Stupor x
Aseptic necrosis x x x x x
Hypogammaglobulinaemia x x x x x x x x x x x x x x x x x
Deep vein thrombosis x x x x x x x x x x x x x x x x x x x x
Cranial nerve paralysis x x x
Neck stiffness x
Allergic cutaneous angiitis x
Necrolysis epidermal x
Impaired healing x
Bone marrow depression x x x x x x
Skin necrosis x x x x x x x x x x x x x x x x
Arterial thrombosis x x x x x x x x x x x x x x x x x x
Blindness transient x x x x x x x x x x x x x x x
Malnutrition x
Skin hyperpigmentation x x x x x
Leukoderma x x x x
Unspecified disorder of skin and subcutaneous tissue x
Interstitial pneumonia x x x x x x x x x x x x x x x x x
Vaginal discharge x x x x x x x x x x x x x x x x x x x x
Abdominal discomfort x
Speech impairment NOS x x x x x x x x x x x x x
Motor dysfunction x x x
Nail changes x x x x x
Hypervigilance x
Neurotoxicity x x
Abdominal distress x x x x x x x x x x x x x x x x x x
Hepatotoxicity x x x x x x x x x x x x
Lung infiltration x x x x x
Hepatic enzyme increased x x x x x x
Gastrointestinal ulcer x
Paresthesia of limbs x
Hepatic fibrosis x
Lung fibrosis interstitial x x x x x
Taste metallic x
Diabetic x
Erectile dysfunction x x x x x x x x x x x x x x x x x x x x
Azotaemia x x x x x x x x x x x x x x x x x x x x
Sepsis x x x x x x x x x x x x x x x x x
Skin depigmentation x
Hepatobiliary disease x x x x x x
Hepatitis acute x x x x x x x x x x x x x x
Leukoencephalopathy x x x x x x x x x x x x x x x x
Pneumonia cytomegaloviral x x x x x x x x
Eruption x
Scald x x x x x x x x x x
Mucosal inflammation x x x x x
Cognitive impairment x x x x x x x x x x x x x x x x x x x
Anaphylactoid reaction x x x x x x x x x x x x x x x x x
Chronic liver disease x x x x
Hepatic atrophy x x x x x
Lymphadenopathy x x x x x x x x x x x x x x x x
Dementia x x x x x x
Pulmonary lymphoma x
Neurological impairment x
Paralysis x
Reaction gastrointestinal x x x x x x x x x x
Visual disturbance x
Alveolitis x x x x x x x x x
Serum albumin decreased x x x x x x x x x x x x x x x
Obstructive airways disorder x x x x x x x x x x x x x x x x x
Hypoxemia x x x x x
Radiculopathy x
Hyperuricaemia x
Haematocrit decreased x x x x x x x x x x x
Febrile neutropenia x
Partial seizures x x
Dry cough x
Infestation NOS x
Blood and lymphatic system disorders x x x x x x x x x x x
Ear and labyrinth disorders x
Thromboembolic event x x x x x x x x x x x x x x x x x x x
Carcinogenicity x x x x x
Lung infection x
Raised liver function tests x x x x x x x x x x x
Insomnia x
Psoriatic plaque x x x
Ocular discomfort x x x x x x x x x x x x x x x x x
Gastrointestinal ulcer haemorrhage x x x x x x x x x x x x x x x x x
Gastrointestinal toxicity x
Respiratory failure x x x x x x x x x x x x
Urine output x
Hepatic insufficiency x
Nuchal rigidity x x x
Retinal vein thrombosis x x x x x x x x x x x x x x x x x x x x
Pneumocystis jirovecii pneumonia x x x x x x x x x x x x x x x
Soft tissue necrosis x x x x x x x x x x x x x x x
Herpes simplex hepatitis x x
Appetite absent x
Somnolence x x x x
Mood alteration NOS x x x x x x x x x x x x x x x x x x x
Loss of libido x x x x x x x x x x x x x x x x x x x x
CNS toxicity x x x
Visual impairment x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

METHOTREXATE (METHOTREXATE SODIUM) / METOJECT

Side effects:91
Source:Health Canada

formerly Amethopterine / Methotrexate

Side effects:98
Source:FDA

methotrexate

Side effects:113
Source:FDA Structured Product Label

Methotrexate

Side effects:116
Source:BC Cancer

METHOTREXATE

Side effects:117
Source:FDA Structured Product Label

METHOTREXATE

Side effects:118
Source:FDA Structured Product Label

METHOTREXATE

Side effects:119
Source:FDA Structured Product Label

METHOTREXATE SODIUM / METHOTREXATE SODIUM

Side effects:119
Source:FDA

METHOTREXATE

Side effects:120
Source:FDA Structured Product Label

METHOTREXATE

Side effects:120
Source:FDA Structured Product Label

Methotrexate tablets / Methoblastin, Tablet

Side effects:127
Source:Medsafe

METHOTREXATE

Side effects:128
Source:FDA Structured Product Label

Methotrexate

Side effects:128
Source:FDA Structured Product Label

METHOTREXATE

Side effects:130
Source:FDA Structured Product Label

Methotrexate; CAS number: 59-05-2 / Methoblastin tablets

Side effects:151
Source:medicines.org.au

Methotrexate / Name of Drug

Side effects:157
Source:medicines.org.au

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label