Search results :

Paclitaxel

More information: STITCH, PubChem (stereo-specific compounds: 1, 2) and possibly Wikipedia

ATC Code: L01CD01

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Leukopenia very common, 72% - 90% x x x x x x x x x x x x x x x x x x x
Neutropenia rare — 3% - 100% x x x x x x x x x x x x x x x x x x x x
Alopecia very common, 87% - 94% x x x x x x x x x x x x x x x x x x x x
Anaemia uncommon — 4% - 97% x x x x x x x x x x x x x x x x x x x x
Diarrhoea rare, 5% - 90% x x x x x x x x x x x x x x x x x x x x
Peripheral sensory neuropathy 71% x x x x x
Nausea postmarketing — 8% - 70% x x x x x x x x x x x x x x x x x x x x
Flushing common — 28% x x x x x x x x x x x x x x x x x x x
Thrombocytopenia very common, 2% - 70% x x x x x x x x x x x x x x x x x x x x
Infection postmarketing — 0.249% - 38% x x x x x x x x x x x x x x x x x x x x
Vomiting 4% - 70% x x x x x x x x x x x x x x x x x x x x
Mucosal inflammation 4% - 45% x x x x x x x x x x x x x x x x x x x x
Anorexia very rare — 25% x x x x x x x x x x x x x x x
Oral candidiasis very common x x x x x x
Pharyngitis very common x
Skin ulcer very common x
Swelling very common x x x
Phosphatase alkaline increased very common x x
Dry skin very common x x x
Neurotoxicity very common x x x x x x x x x x x x x x x
Myelosuppression very rare, very common x x x x x x x x x x x x
Haemorrhage very common, 2% - 14% x x x x x x x x x x x x x x x x x x x
Herpes simplex rare — 11% - 38% x x x x x x x x x x x x x x x
Rash postmarketing — 9% - 14% x x x x x x x x x x x x x x x x x x x
B-cell type acute leukaemia 9% - 14% x x
Oedema postmarketing — 10% x x x x x x x x x x x x x x x x x x x
Pain common, very common x x x x x x x x x x x x x x
Upper respiratory tract infection common, very common x x x x x x x x x x x x x x x
Hypotension very rare — 3% - 17% x x x x x x x x x x x x x x x x x x x x
Candida infection 7% - 9% x x x x x x x x x x x x x
Neuropathy peripheral very common, 1% - 15% x x x x x x x x x x x x x x x x x x
Chest pain postmarketing, very common x x x x x x x x x x x x x x x x x x x
Rhinitis rare, very common x x x x
Chills rare, very common x x x x x x x x x x x x x x
Skin discolouration rare, very common x x x x x x x x x x x x x x
Tenderness rare, very common x x x x x x x x x x x x x
Cryptosporidiosis infection 7% x x x x x x x x x x x
Cough very rare — 6% - 7% x x x x x x x
Fatigue 4% - 8% x x x x
Pancreatitis acute common x
Conjunctivitis postmarketing, common x x x x x x x x x x x x
Dysgeusia common x x x x
Dyspepsia common x x x
Localised oedema common x
Deafness neurosensory common x
Hypoaesthesia common x x x
Hypokalaemia common x x x
Influenza common x
Eye pruritus common x x
Keratitis common x x x x
Keratoconjunctivitis sicca common x x
Melaena common x
Nervousness common x
Palpitations common x
Syncope common x
Urinary tract infection common x x x x x x x x x x x x x x x x
Dry mouth common x x x
Hypokinesia common x
Mouth ulceration common x x x
Skin necrosis common x
Eye pain common x x
Lacrimation increased postmarketing, common x x x x x x x x x x x x
Decreased appetite common x x x
Thinking abnormal common x
Visual acuity reduced postmarketing, common x x x
Eye irritation common x x
Skin fibrosis common x
Madarosis common x x
Blood bilirubin increased common x x x x
Dry eye common x x x
Vision blurred common x x x x
Neuropathy common x x x x x x x x x x x x x x x x x x
Necrotizing enterocolitis common x
Visual disturbance rare — 13% x x x x x x x x x x x x x x x x x x x
Gait disturbance common x x x
Febrile neutropenia common, 1% - 55% x x x x x x x x x x x x x x x x x x x
Encephalopathy acute common x
Abnormal vision common x x
Gastrointestinal disorder postmarketing, 3.48% - 47.8% x x x x x
Connective tissue disorder 0.746% - 5.97% x x x x
Asthenia postmarketing — 1% - 47% x x x x x x x x x x x x x x x x x x x x
Gamma-glutamyltransferase increased 3% x
Bradycardia rare — 1% - 3% x x x x x x x x x x x x x x x x x x x
Dehydration postmarketing — 5% x x x x x x x x x x x x x x x x x x
Cardiomyopathy uncommon, common x x
Epistaxis rare, common x x x x x
Cystoid macular oedema postmarketing, common x x x
Myocardial infarction rare, common x x x x x x x x x x x x x x
Peripheral motor neuropathy rare, common x x x x x x x x x x
Insomnia rare, common x x x x
Ventricular tachycardia very rare, common x x x x x x x x x x x x x
Ventricular bigeminy very rare, common x x x x x x x x x x x x x
Pseudomembranous colitis very rare, common x x
Meningitis cryptococcal 2% - 3% x x x x x x x x x x x
Arthralgia rare — 1% - 2% x x x x x x x x x x x x x x x x x x x x
Dyspnoea postmarketing — 1% - 12% x x x x x x x x x x x x x x x x x x
Tachycardia very rare — 2% x x x x x x x x x x x x x x x x x
Myalgia 1% - 44% x x x x x x x x x x x x x x x x x x x x
Leukoencephalopathy 2% x x x x x x x x x x x
Malnutrition postmarketing, 1.99% - 25.9% x x x x x
Hypersensitivity postmarketing — 1% - 14% x x x x x x x x x x x x x x x x
Body temperature increased postmarketing — 1% - 14% x x x x x x x x x x x x x x x x x x x
Hypertension uncommon, 1% x x x x x x x x x x x x x x x x x x x
Injection site reaction postmarketing — 1% - 13% x x x x x x x x x x x x x x x x x x x x
Nail changes very common, 1% x x x x x x x x x x x x x x x x x
Nervous system disorder postmarketing, 0.746% - 12.7% x x x x x
Angioedema uncommon x x
Contusion uncommon x x
Hyperglycaemia uncommon x x x x x x x x x x x x
Hypocalcaemia uncommon x x
Hypoglycaemia uncommon x x
Hyponatraemia uncommon x x x
Septic shock uncommon x x
Thrombophlebitis uncommon x x x
Weight decreased uncommon x x x
Polydipsia uncommon x x
Hypophosphataemia uncommon x x
Hypoalbuminaemia uncommon x x
Fluid retention uncommon x x x x x
Tumour necrosis uncommon x x
Extrasystoles uncommon x x x x x x x x x x x x x
Respiratory distress uncommon x x
Generalized urticaria uncommon x x
Metastatic pain uncommon x x
Nail pigmentation uncommon x x x
Pneumothorax 1% x x
Neutropenic sepsis 1% x x x
Pneumonia postmarketing — 3% - 4% x x x x x x x x x x x x x x x x x x x
Thrombosis rare, uncommon x x x x x x x
Infestation NOS postmarketing, 0.249% - 4.98% x x x x x
Anaphylactic shock very rare — uncommon x x
Ascites very rare — common x x x x x x x x x
Atrial fibrillation very rare — common x x x x x x x x x x x x x
Atrioventricular block very rare — common x x x x x
Mental disorder postmarketing, 0% - 5.97% x x x x x
Cellulitis postmarketing — very common x x x x x x x x x x x x x x x x x x
Colitis postmarketing x x
Constipation very rare — 18% x x x x x x x x x x x x x x x
Dermatitis exfoliative very rare — very common x x
Scleroderma postmarketing x x x x x x x x
Dizziness very rare — common x x x x x x x x x x x x x
Erythema multiforme very rare — uncommon x x
Oesophagitis very rare — common x x x x x x x x x x x x
Extravasation postmarketing — very common x x x x x x x x x x x x x x x x x x x
Eye disorder postmarketing x x x x x
Fibrosis postmarketing x x x x x x x x x x x x x x
Vitreous floaters postmarketing x x x x x x x x x
Headache very rare — common x x x x x x x x x x x x x
Cardiac arrest rare x x x x x
Cardiac disorder postmarketing x x x x x
Cardiac failure rare x
Cardiac failure congestive postmarketing — common x x x x x x x x x x x x x x x x x
Blood disorder postmarketing x x
Hepatic encephalopathy postmarketing x x x x x x x x x x x x x x x x
Hyperaesthesia postmarketing x x x x x x x x x
Orthostatic hypotension very rare — common x x x x x
Immune system disorder postmarketing x x x x
Intestinal obstruction postmarketing — 4% x x x x x x x x x x x x x x x x x
Intestinal perforation postmarketing — common x x x x x x x x x x x x x x x
Acute myeloid leukaemia very rare — uncommon x x
Mediastinal disorder postmarketing, 0% - 7.46% x x x x x
Hypertonia rare x
Myelodysplastic syndrome very rare — uncommon x x
Necrosis postmarketing x x x x x x x x x x x x x x
Pancreatitis postmarketing, rare x x x x x x x x x x x x x x x
Ileus paralytic very rare — common x x x x x x x x x x x x x x x x
Paraesthesia postmarketing x x x x x x x x x x x x x
Peritonitis rare x x x x x x x x x x x x x
Phlebitis postmarketing x x x x x x x x x x x x x x x
Pleural effusion postmarketing, rare x x x x x x x x x x x x
Pruritus postmarketing — very common x x x x x x x x x x x x x x x x x x
Pulmonary embolism postmarketing, rare x x x x x x x x x x x x x x
Pulmonary fibrosis postmarketing, rare x x x x x x x x x x x x x x x
Scotoma rare x x x x x x x x x x x
Convulsion very rare — common x x x x x x x x x x
Shock very rare — uncommon x x x x x x x x x x
Sinusitis rare x x x
Stevens-Johnson syndrome very rare — uncommon x x x x x x x x x x x x x x x x x
Erythema postmarketing — very common x x x x x x x x x x x x x x x x x x
Urticaria very rare — uncommon x x x x
Angiopathy postmarketing x x x x x
Disorder sight postmarketing x
Photopsia postmarketing x x x x x x x x x
Onycholysis very rare — uncommon x x x x
Cranial nerve paralysis postmarketing x x x x
Injection site swelling rare x x x x x x x x x x x x x
Necrolysis epidermal very rare — uncommon x x
Accidental injury rare x
Hepatic necrosis postmarketing, rare x x x x x x x x x x x x x x x x
Nerve injury postmarketing x x x x x x x x x x x x x
Colitis ischaemic postmarketing — common x x x x x x x x x x x x x x x x
Photosensitivity reaction postmarketing x x x x
Unspecified disorder of skin and subcutaneous tissue postmarketing, 0% - 5.22% x x x x x
Interstitial pneumonia postmarketing, rare x x x x x x x x x x x x x x x x
Radiation pneumonitis postmarketing, rare x x x x x x x x x x x x x x x x x
Fatal outcomes postmarketing — very common x x
Malaise postmarketing — very common x x x x x x x x x x x x x x x x
Blood creatinine increased rare x x x x x x x x x x x
Skin exfoliation postmarketing x x x x x x x x x x x x x x
Throat sore postmarketing x x x x x x x x x x
Left ventricular dysfunction postmarketing, rare x x x
Sepsis postmarketing, rare x x x x x x x x x x x x x x x x
Autonomic neuropathy very rare — common x x x x x x x x x x x x x x x x
Thrombosis mesenteric vessel very rare — common x x
Caecitis postmarketing x x x x x x x x x x x x x
Breast cancer stage IV rare x
Induration postmarketing x x x x x x x x x x x x x x x
Redness postmarketing x x x x x x x x x x
Neutropenic enterocolitis postmarketing x x x x x x x x x x x x x x x
Rash maculo-papular postmarketing x x x x x x x x x x x x x x x
Visual evoked potentials abnormal postmarketing x x x x x x x x x x x x x
Vocal cord paresis postmarketing x x x
Ventricular failure postmarketing x x x x x x x x x
Ear and labyrinth disorders postmarketing x x x x
Respiratory failure postmarketing, rare x x x x x x x x x
Recall phenomenon postmarketing, rare x x x x
Radiation recall reaction (dermatologic) rare x
Tingling sensation postmarketing x x x x x x x x x x
Ataxia very rare, postmarketing x x x x x x x x x x x x x x
Confusional state very rare, postmarketing x x x x x x x x x x x
Toxic epidermal necrolysis very rare, postmarketing x x x x x x x x x x x x x x x
Supraventricular tachycardia very rare, postmarketing x x x x x x x x x x x x x x x x x
Tinnitus very rare — common x x x x x x x x x x x x x x x
Vertigo very rare — common x x x x x x x x x x x x
Encephalopathy very rare, postmarketing x x x x x
Tonic-clonic seizures very rare, postmarketing x x x x x x x x x x x x x
Ototoxicity very rare, postmarketing x x x x x x x x x x x x
Coronary artery stenosis very rare x x
Neutropenic colitis very rare x
Drug interaction very rare x x x x x x x x x x x x
Hearing impaired very rare, postmarketing x x x x x x x x x x x x
Abdominal distension x x
Abdominal pain x x x x x x x x x x x x
Adenocarcinoma x
Amblyopia x
Anxiety x x
Arrhythmia x x x x x x x x x x x x x x x x x
Back pain x x x x x x x x x x x x x x x
Bone disorder x
Metabolic encephalopathy x
Breast disorder x x
Bronchitis x
Transient ischaemic attack x x
Neck pain x x
Chest wall pain x x
Cholangitis x
Cyst x
Dysphagia x x
Depression x
Dermatitis x x x
Dermatitis atopic x
Drug hypersensitivity x
Dyskinesia x x
Dysuria x x x
Ear pain x x
Embolism x
Flank pain x x
Flatulence x x
Folliculitis x x
Gastrooesophageal reflux disease x x
Glossodynia x x
Haematuria x x
Haemolytic uraemic syndrome x
Haemoptysis x
Hepatomegaly x x
Herpes zoster x x
Hoarseness x x
Hyperbilirubinaemia x
Hyperhidrosis x x
Pulmonary hypertension x
Hypotrichosis x x
Infarction x x
Renal failure acute x
Cramps of lower extremities x
Lethargy x x x
Systemic lupus erythematosus x
Lymphoedema x x
Lymphopenia x x
Breast pain x x
Cramp muscle x x
Musculoskeletal pain x x
Fungal infection x x
Nail disorder x x
Nasal congestion x x
Nasopharyngitis x x
Neoplasm x x x
Neuralgia x x
Night sweats x x
Nocturia x x
Opportunistic infection x x x x x x x x x x x
Pain in extremity x x x
Pancytopenia x x x
Polyp x
Polyuria x x
Prurigo x x
Thrombotic thrombocytopenic purpura x
Respiratory tract infection x x x x
Congenital skin disorder x x x x x x x x x x x x
Skin disorder x x
Skin lesion x x
Muscle spasms x x
Stomatitis x x x
Cerebrovascular accident x x
Sinus tachycardia x x x x x x x x x x x x x x x
Tremor x x
Tumour lysis syndrome x
Pollakiuria x x
Urinary incontinence x x
Urinary tract disorder x x x
Venous thrombosis x x x x x x x x x x x
Viral infection x x
Vitiligo x x
Weight increased x x
Wheezing x x
Immunocompromised x x x x x x x x x x x
Sinus bradycardia x x x x x x x x x x x x x
Agitation x x x
Oedema peripheral x x x
Squamous cell carcinoma of lung x
Atrioventricular block complete x x x x x x x x x x x
Swelling face x x
Electrolyte abnormality x
Hypomagnesaemia x
Myocardial ischaemia x x
Muscular weakness x x
Bone pain x x x
Hyporeflexia x x
Aspartate aminotransferase increased x x x x
Alanine aminotransferase increased x x x
Polyneuropathy x x
Sensory disturbance x x
Sinus congestion x x
Skin hyperpigmentation x x
Interstitial lung disease x
Lightheadedness x
Rash macular x x
Nail discolouration x x x x x x x x x x x x
Injection site infection x x
Oral pain x x
Dyspnoea exertional x x
Nasal dryness x x
Abdominal pain upper x x
Abdominal pain lower x x
Areflexia x x
Rash erythematous x x
Dizziness postural x x
Neurological symptom x x x x x x x x x x x x x
Scintillating scotoma x x x x
Dry throat x
Chest discomfort x x
Respiratory sounds decreased x x
Productive cough x x
Gingival pain x x
Groin pain x x
Pain of skin x x
Onychomadesis x x
Rectal haemorrhage x x
Hepatobiliary disease x x x
Macular oedema x
Blood pressure systolic decreased x
Peripheral coldness x x
Sensory loss x x
Malignant neoplasm of pancreas x
Influenza-like symptoms x x x x x x x x x
Hyperpyrexia x x
Rigors x x
Red blood cell count decreased x x
Pruritus generalised x x
Blood pressure increased x x
Rash generalised x x
Hypoaesthesia oral x x
Influenza like illness x x
Electrocardiogram abnormal x x x x x x x x x x x x x x x x x
Pulmonary thromboembolism x x x x x
Nail discomfort x x
Pigmentation disorder x x
Blood glucose increased x x
Nephropathy toxic x x x x x x x x x x x
Hot flush x x
Sweating increased x x x x x x x x
Haematocrit decreased x x
Hyperlactacidaemia x x
Blood and lymphatic system disorders x x x
Blood alkaline phosphatase increased x
Blood potassium decreased x x
Limb discomfort x x
Anemic x x x x x x x x x x x x
Hypotensive x
Pharyngolaryngeal pain x x
Catheter related infection x x
Nail bed tenderness x x
Raised liver function tests x x x x x x x x x
VIIth nerve paralysis x
Myasthenia x
Ischaemic stroke x
Infusion site reaction x
Infusion site inflammation x
Skin toxicity x x x x x x x x x x x
Infusion site rash x
Ileus x
Rhinorrhoea x x
Rash papular x x
Renal impairment x x x x x x x x x x
Infusion site extravasation x
Loose stools x x
Rhinitis allergic x x
Somnolence x x x
Mood alteration NOS x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

PACLITAXEL

Side effects:43
Source:FDA Structured Product Label

paclitaxel

Side effects:44
Source:BC Cancer

PACLITAXEL / ABRAXANE FOR INJECTABLE SUSPENSION

Side effects:100
Source:Health Canada

PACLITAXEL

Side effects:124
Source:FDA Structured Product Label

paclitaxel / paclitaxel

Side effects:156
Source:EMA

PACLITAXEL / PACLITAXEL FOR INJECTION

Side effects:99
Source:Health Canada

PACLITAXEL / APO-PACLITAXEL INJECTABLE

Side effects:107
Source:Health Canada

PACLITAXEL / TAXOL LIQ IV 6MG/ML

Side effects:111
Source:Health Canada

PACLITAXEL

Side effects:135
Source:FDA Structured Product Label

PACLITAXEL

Side effects:136
Source:FDA Structured Product Label

PACLITAXEL

Side effects:137
Source:FDA Structured Product Label

PACLITAXEL

Side effects:137
Source:FDA Structured Product Label

paclitaxel

Side effects:137
Source:FDA Structured Product Label

PACLITAXEL

Side effects:137
Source:FDA Structured Product Label

PACLITAXEL

Side effects:137
Source:FDA Structured Product Label

Paclitaxel

Side effects:137
Source:FDA Structured Product Label

paclitaxel / paclitaxel

Side effects:261
Source:EMA

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label