| Side effect | Data for drug | Placebo | Labels | 
|  | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 
| Vertigo | 0.926% - 33% | 0.449% - 6.9% |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Dizziness | postmarketing — 7.41% - 33% | 2.69% - 12.4% | x | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Nausea | postmarketing — 13% - 40% | 5.54% - 21.4% | x | x | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Constipation | common, 9.32% - 46% | 3.89% - 13.6% | x | x | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Headache | common, 2.83% - 32% | 3.14% - 22.1% | x | x | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Somnolence | 4.34% - 30.2% | 1.72% - 13.8% |  |  |  |  |  |  | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Vomiting | postmarketing — 3.24% - 17% | 0.599% - 10.4% | x | x | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Dyspepsia | uncommon, 1.4% - 13% |  | x | x | x |  | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Dry mouth | common, 1.13% - 13.1% | 1.2% - 8.29% | x | x | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Flushing | uncommon, 7.69% - 15.8% | 4.43% | x | x | x |  | x | x |  |  |  |  |  |  | x | x |  | x | x | x | x | x | 
| Pruritus | uncommon, 3.03% - 11.9% | 0.985% - 5.76% | x | x | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Sweating | common, 4.2% - 9% | 0.619% - 5.3% | x | x | x |  | x | x | x | x | x | x | x | x |  |  | x |  |  |  | x |  | 
| Asthenia | rare — 0.744% - 12% | 1.23% - 5.99% | x | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Diarrhoea | uncommon, 2.33% - 10% | 4.19% | x | x | x |  | x | x | x |  | x | x | x |  | x | x |  | x | x | x | x | x | 
| Arthralgia | 0.9% - 5.36% | 4.61% - 5.11% |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x |  | x | 
| Insomnia | postmarketing, 0.926% - 10.9% | 1.2% - 3.2% |  |  | x |  |  | x |  |  |  |  |  | x | x | x |  | x | x | x | x | x | 
| Pain worsened | 2.8% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Fatigue | common, 1.7% - 4.2% | 0.898% | x | x | x |  | x | x |  |  |  |  |  |  |  | x |  |  |  |  | x | x | 
| Anorexia | 0.744% - 7.44% | 0.155% - 5.3% |  |  |  | x |  |  | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Orthostatic hypotension | postmarketing — 1.74% - 5.45% | 2.22% |  |  |  | x |  |  | x | x | x | x | x |  | x | x |  | x | x | x |  | x | 
| Sweating increased | postmarketing, 0.463% - 7.44% | 0.246% - 0.749% |  |  |  | x |  |  | x | x | x | x | x |  | x | x | x | x | x | x | x | x | 
| Nasopharyngitis | 1.9% |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Rigors | 0.5% - 3.47% | 0.246% |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Upper respiratory tract infection | 1.4% |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Abdominal pain upper | 1.4% - 4.19% |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x |  | x | 
| Angina pectoris | postmarketing — 1.86% - 1.9% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Hypertension worsened | postmarketing — 1.86% - 1.9% |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Influenza like illness | postmarketing — 0.248% - 1.98% | 0.493% |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Abdominal pain | uncommon, 0.9% - 1.4% |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Influenza | 0.9% |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x | x | x | x | x | 
| Urinary tract infection | 0.9% |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x | x | x | x | x | 
| Alanine aminotransferase increased | postmarketing — 0.8% |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | 
| Red blood cell sedimentation rate increased | postmarketing — 0.7% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Aspartate aminotransferase increased | postmarketing — 0.7% |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x | 
| Dysgeusia | postmarketing — 3.72% |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  | x | x | 
| Rash | uncommon |  | x | x | x | x | x | x | x | x | x | x | x | x |  |  |  |  |  |  | x | x | 
| Flatulence | uncommon |  | x | x | x | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | x | 
| Trembling | postmarketing, uncommon |  | x | x | x |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Weight decreased | 0.5% |  |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Hot flush | 0.5% |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x |  | x | 
| Anxiety NEC | 0.5% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Gamma-glutamyltransferase increased | 0.4% |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x |  |  |  |  |  | x | 
| Liver function test abnormal | 0.4% |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | x | 
| Anaemia | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x |  |  |  |  |  | x | 
| Angina unstable | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Aortic aneurysm | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Rheumatoid arthritis | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Ataxia | postmarketing, uncommon |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x |  |  |  |  | x | x | 
| Atrial fibrillation | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Back injury | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Bipolar disorder | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Blister | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Concussion | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Breast cancer | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Bronchitis | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x | x | x |  | x | 
| Bursitis | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Cardiovascular disorder | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Neck pain | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x | x | x |  | x | 
| Chest wall pain | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Cholelithiasis | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x |  | x | 
| Infection | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Contusion | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Cough | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Dysphagia | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Dehydration | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Dermatitis | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x | 
| Dermatitis atopic | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Dermatitis contact | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Diabetes mellitus | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Diverticulitis | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x | x | 
| Dysarthria | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Dysmenorrhoea | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Ear pain | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Eczema | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Emotional disturbance NOS | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Epistaxis | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Erysipelas | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Eye injury | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Eyelid disorder | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Face injury | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Faecalith | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Food poisoning | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Gastroenteritis | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x | x | x | x | x | 
| Gastrooesophageal reflux disease | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Gout | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x | x | 
| Seasonal allergy | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Head injury | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Cardiac murmur | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Haematoma | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Haematuria | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | x | 
| Herpes simplex | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Herpes zoster | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Hiccups | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Hordeolum | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Hypercalcaemia | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Hyperglycaemia | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x | x | 
| Hyperlipidaemia | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Hypertriglyceridaemia | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Hypoaesthesia | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Hypocalcaemia | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Hypokalaemia | postmarketing — 0.3% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Hypothyroidism | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Cerumen impaction | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Inflammation | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Irritability | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x |  | x | 
| Arthropathy | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x | x | 
| Calculus of kidney | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Labyrinthitis | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Laryngitis | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Fungal infection | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Ingrowing nail | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Nasal congestion | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Neck injury | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Neuralgia | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Night sweats | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x |  | x | 
| Nocturia | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Osteopenia | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Osteoporosis | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Otitis externa | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Otitis media | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Pain | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Pallor | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Piloerection | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | x | 
| Prostatitis | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Prurigo | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Rales | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Rectal prolapse | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Rhonchi | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Rosacea | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Sinus headache | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Sinusitis | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x | x | x | x | x | 
| Skin disorder | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x | 
| Skin ulcer | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Sleep apnoea syndrome | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Soft tissue injury | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Tachycardia | postmarketing — uncommon |  | x | x | x | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | x | 
| Sinus tachycardia | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Tendonitis | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Tendon injury | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Thrombocytopenia | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Thyroid neoplasm | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Tracheitis | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Erythema | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Pollakiuria | postmarketing, uncommon |  |  |  |  | x |  |  | x | x | x | x | x |  | x |  | x | x | x | x |  | x | 
| Urinary incontinence | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Uterine leiomyoma | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Viral infection | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x | x | x |  | x | 
| Wound infection | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Laceration | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Helicobacter infection | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Muscle strain | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Micturition urgency | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Burning sensation | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Apathy | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x |  |  |  |  | x | x | 
| Photopsia | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Plantar fasciitis | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Deep vein thrombosis | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Neck stiffness | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x | 
| Blood urea increased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x | 
| Bone pain | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Eye pain | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Dry skin | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Sinus congestion | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Joint swelling | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Urinary hesitation | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Lacrimation increased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Viral diarrhoea | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Acute myocardial infarction | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Arthralgia of temporomandibular joint | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Haemoglobin decreased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Polyarthralgia | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Joint stiffness | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Vaginal discharge | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Malaise | postmarketing, uncommon |  |  |  |  | x |  |  | x | x | x | x | x |  | x | x | x | x | x | x | x | x | 
| Myalgia | postmarketing, uncommon |  |  |  |  |  |  | x |  |  |  |  |  | x | x |  | x | x | x | x | x | x | 
| Joint crepitation | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Chest tightness | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Vascular insufficiency | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Cold sweat | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Decreased appetite | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x |  | x | 
| Abdominal discomfort | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Abdominal pain lower | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Abdominal tenderness | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Retching | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Menometrorrhagia | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Disturbance in attention | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x |  | x | 
| Abnormal behaviour | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Euphoric mood | postmarketing, uncommon |  |  |  |  | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Dry throat | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Faeces discoloured | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Small intestinal obstruction | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Blood creatinine increased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Productive cough | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Groin pain | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Haematocrit increased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Vaginal cyst | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Wound haemorrhage | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Erectile dysfunction | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x | x | 
| Mammogram abnormal | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Back disorder | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Rectal haemorrhage | postmarketing — 0.3% |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x | x | 
| Hepatobiliary disease | postmarketing, uncommon |  |  |  |  |  | x |  |  |  |  |  |  |  |  | x | x | x | x | x |  | x | 
| Otitis media serous | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Change of bowel habit | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Dry eye | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Benign breast neoplasm | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Muscle injury | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Red blood cell count decreased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Red blood cell count increased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Joint sprain | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Ligament injury | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Wrist fracture | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Hand fracture | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Nasal oedema | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Pruritus generalised | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Lymphadenopathy | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Tooth abscess | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Poor peripheral circulation | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Genital itching female | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Sinus pain | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Inflammation localised | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Low density lipoprotein increased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Haemoglobin increased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Sexual dysfunction | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Renal pain | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Gait disturbance | postmarketing, uncommon |  |  |  |  | x |  |  | x | x | x | x | x |  |  | x |  |  |  |  | x | x | 
| Abscess limb | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Blood glucose abnormal | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Blood glucose increased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Blood cholesterol increased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Bladder infection | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Ear infection | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Throat irritation | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| C-reactive protein increased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Limb injury | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Foot infection fungal NOS | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Haematocrit decreased | postmarketing — 0.3% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Scleral haemorrhage | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| White blood cell count increased | postmarketing — 0.3% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Ear congestion | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Infestation NOS | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  | x | 
| Ear and labyrinth disorders | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x |  | x | 
| Blood alkaline phosphatase increased | 0.3% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Blood amylase increased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Blood lactate dehydrogenase increased | 0.3% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Eczema exacerbated | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Osteoarthritis aggravated | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Neutrophil count decreased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Lymphocyte count increased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Blood potassium abnormal | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Exacerbation of hot flushes | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Breast cancer invasive NOS | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Dyspepsia aggravated | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Alanine aminotransferase decreased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Aspartate aminotransferase decreased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Constipation aggravated | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x |  | x | 
| Pancreatitis aggravated | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Lip blister | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Protein total decreased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Hyperkeratosis | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Headache aggravated | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Tooth infection | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Respiratory tract infection viral | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Postoperative wound complication | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Red cell distribution width increased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Ear discomfort | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Musculoskeletal stiffness | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Musculoskeletal discomfort | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Mean platelet volume decreased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Rhinorrhoea | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Gastrointestinal infection | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Abrasion NOS | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Mental disability | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Blood in stool | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Feeling abnormal | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Renal impairment | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Bone spur | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Loose stools | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Rhinitis allergic | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Gastrointestinal tract irritation | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Anaphylactic shock | postmarketing, rare |  | x | x | x | x | x | x | x | x | x | x | x |  |  |  |  |  |  |  | x | x | 
| Angioedema | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Anxiety | postmarketing, rare |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Mental disorder | postmarketing |  |  |  |  |  | x |  |  |  |  |  |  | x |  | x | x | x | x | x |  | x | 
| Breast disorder | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Coma | postmarketing |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  | x | x | 
| Confusional state | postmarketing — uncommon |  | x | x | x | x | x | x | x | x | x | x | x | x |  | x |  |  |  |  | x | x | 
| Connective tissue disorder | postmarketing |  |  |  |  |  | x |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Cyst | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Deafness | postmarketing |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  |  |  | 
| Delirium | postmarketing |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | x | x |  |  | 
| Drug abuse | postmarketing |  |  |  | x |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dyspnoea | postmarketing — uncommon |  | x | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | x | 
| Dysuria | rare |  |  | x | x | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | x | 
| Endocrine disorder | postmarketing |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Eye disorder | postmarketing |  |  |  |  |  | x | x |  |  |  |  |  | x |  | x | x | x | x | x |  | x | 
| Body temperature increased | postmarketing, uncommon |  |  |  |  | x |  | x | x | x | x | x | x | x | x |  | x | x | x | x | x | x | 
| Gastrointestinal haemorrhage | postmarketing, uncommon |  |  |  |  | x |  |  | x | x | x | x | x |  |  | x |  |  |  |  | x | x | 
| Hallucination | postmarketing, rare |  | x | x | x | x | x | x | x | x | x | x | x |  |  |  |  |  |  |  | x |  | 
| Hepatitis | postmarketing |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  | x | x | 
| Hypersensitivity | postmarketing — 1.4% |  | x | x | x | x | x | x | x | x | x | x | x | x |  | x |  |  |  |  | x | x | 
| Hypertension | postmarketing — 2.3% - 2.33% |  |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Hypoglycaemia | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Hypotension | postmarketing, uncommon |  |  |  |  | x |  |  | x | x | x | x | x | x |  | x |  |  |  |  | x | x | 
| Immune system disorder | postmarketing |  |  |  |  |  | x |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Miosis | postmarketing |  |  |  |  | x | x |  | x | x | x | x | x |  |  |  |  |  | x | x |  |  | 
| Movement disorder | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  |  | 
| Mydriasis | postmarketing |  |  | x |  |  | x | x |  |  |  |  |  |  |  |  |  |  | x | x |  |  | 
| Neoplasm | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Nervous system disorder | postmarketing |  |  |  |  |  | x |  |  |  |  |  |  | x |  | x | x | x | x | x |  | x | 
| Nervousness | postmarketing |  |  |  | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Nightmare | postmarketing, rare |  | x | x | x |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Palpitations | postmarketing, uncommon |  |  |  |  | x |  |  | x | x | x | x | x |  | x |  | x | x | x | x | x | x | 
| Paraesthesia | postmarketing — uncommon |  | x | x | x | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | x | 
| Polyp | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Proteinuria | postmarketing |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  |  |  | 
| Pulmonary oedema | postmarketing |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  | x | x | 
| Pulmonary embolism | postmarketing |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  |  |  | 
| Convulsion | postmarketing, rare |  | x | x | x | x | x | x | x | x | x | x | x | x |  | x |  |  |  |  | x | x | 
| Shivering | postmarketing |  |  |  |  | x |  |  | x | x | x | x | x |  | x |  | x | x | x | x | x | x | 
| Shock | postmarketing — uncommon |  | x | x | x |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Sleep disturbance | postmarketing, rare |  | x | x | x |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Speech disorder | postmarketing |  |  |  |  | x | x | x | x | x | x | x | x |  |  |  |  |  | x | x |  |  | 
| Stevens-Johnson syndrome | postmarketing |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  | x | x | 
| Stomatitis | postmarketing |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  |  |  | 
| Syncope | postmarketing |  | x | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | x | 
| Tinnitus | postmarketing, uncommon |  |  |  | x | x |  | x | x | x | x | x | x |  | x |  | x | x | x | x | x | x | 
| Tremor | postmarketing — 0.5% |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Urinary tract disorder | postmarketing |  |  |  |  |  | x |  |  |  |  |  |  |  |  | x | x | x | x | x |  | x | 
| Urticaria | postmarketing, uncommon |  |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Angiopathy | postmarketing, rare |  |  |  |  |  | x |  |  |  |  |  |  | x |  | x | x | x | x | x |  | x | 
| Urinary retention | postmarketing — uncommon |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Hepatic failure | postmarketing |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  | x | x | 
| Agitation | postmarketing, uncommon |  |  |  | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Mood swings | postmarketing, rare |  | x | x | x |  | x | x |  |  |  |  | x | x |  |  |  |  |  |  |  |  | 
| Hypokinesia | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Cataract | postmarketing, uncommon |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  |  | x | 
| Panic attack | postmarketing |  |  |  | x |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Migraine | postmarketing, uncommon |  |  |  |  | x |  |  | x | x | x | x | x |  | x |  | x | x | x | x | x | x | 
| Myocardial ischaemia | postmarketing |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  |  |  | 
| Hyperreflexia | postmarketing |  |  |  |  | x |  | x | x | x | x | x | x |  |  |  |  |  |  |  | x | x | 
| Malnutrition | postmarketing |  |  |  |  |  | x |  |  |  |  |  |  | x |  | x | x | x | x | x |  | x | 
| Unspecified disorder of skin and subcutaneous tissue | postmarketing |  |  |  |  |  | x |  |  |  |  |  |  | x |  | x | x | x | x | x |  | x | 
| Dysphoria | postmarketing, rare |  | x | x | x |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Respiratory depression | very rare — rare |  | x | x | x |  | x | x |  |  |  |  |  | x |  |  |  |  |  |  | x | x | 
| Muscle contractions involuntary | postmarketing, rare |  | x | x | x |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Suicidal tendency | postmarketing |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  | x | x | 
| Hepatic enzyme increased | very rare, postmarketing |  | x | x | x | x | x | x | x | x | x | x | x |  |  |  |  |  |  |  |  |  | 
| Tolerance development | postmarketing |  |  |  | x |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Strangury | rare |  | x | x | x |  | x | x |  |  |  |  |  |  | x | x | x | x | x | x |  | x | 
| Vision blurred | postmarketing — uncommon |  | x | x | x |  | x | x |  |  |  |  |  |  | x | x | x | x | x | x |  | x | 
| Hyperkinesia | postmarketing |  |  |  | x |  |  | x |  |  |  |  |  | x |  |  |  |  |  |  | x | x | 
| Gastrointestinal symptom NOS | postmarketing |  |  |  | x |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Bradycardia | postmarketing — uncommon |  | x | x | x |  | x | x |  |  |  |  |  |  |  | x |  |  |  |  | x | x | 
| Blood pressure increased | rare |  | x | x | x |  | x | x |  |  |  |  |  |  | x | x | x | x | x | x |  | x | 
| Electrocardiogram abnormal | postmarketing |  |  |  |  | x |  |  | x | x | x | x | x | x |  |  |  |  |  |  |  |  | 
| Visual disturbance | rare |  | x | x | x | x | x | x | x | x | x | x | x |  |  | x |  |  |  |  |  | x | 
| Serotonin syndrome | postmarketing |  |  |  |  | x |  | x | x | x | x | x | x | x |  |  |  |  |  |  | x | x | 
| Blood and lymphatic system disorders | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Coordination disturbance | postmarketing, rare |  | x | x | x | x | x | x | x | x | x | x | x |  |  |  |  |  |  |  |  |  | 
| Orthostatic dysregulation | postmarketing — uncommon |  | x | x | x |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Asthma | very rare — uncommon |  | x | x | x |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Hyponatraemia | very rare, postmarketing |  | x | x | x |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Inappropriate antidiuretic hormone secretion | very rare, postmarketing |  | x | x | x |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Abdominal distension |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Albuminuria |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Amblyopia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Amnesia |  |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  | x |  | 
| Haemolytic anaemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Anosmia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Appendicitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  |  | 
| Arrhythmia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Arthritis |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x |  | 
| Atrial flutter |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Back pain |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | x | 
| Bacteriuria |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Biliary tract disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Blepharitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Bone disorder |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | x | x | x | x |  |  | 
| Bronchospasm |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Carpal tunnel syndrome |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Cellulitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x |  | 
| Chest pain |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | x | 
| Cholecystitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  |  | 
| Conjunctivitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Cystitis |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x |  | 
| Libido decreased |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x | 
| Delusion |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Depersonalisation |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x |  | 
| Depression |  |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  | x |  | 
| Diverticulum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | 
| Dysthymic disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Ecchymosis |  |  |  |  |  |  |  | x |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Cyst epidermal |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Toxic epidermal necrolysis |  |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  |  |  | 
| Eructation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Gastritis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x | x | 
| Gastrointestinal disorder |  |  |  |  |  |  | x |  |  |  |  |  |  | x |  | x | x | x | x | x |  | x | 
| Gynaecomastia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Hair disorder |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Breath odour |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Cardiac disorder |  |  |  |  |  |  | x |  |  |  |  |  |  | x |  | x | x | x | x | x |  | x | 
| Haematemesis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Haemoptysis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Haemorrhage |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Herpangina |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hypercholesterolaemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Hyperaesthesia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Hyperkalaemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hyperventilation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Insomnia NEC |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Irritable bowel syndrome |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Lacrimal disorder |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x |  | 
| Cramps of lower extremities |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Lethargy |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Lymphatic disorder |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Breast pain |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Mediastinal disorder |  |  |  |  |  |  | x |  |  |  |  |  |  | x |  | x | x | x | x | x |  | x | 
| Melaena |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Menstrual disorder |  |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  |  |  | 
| Cramp muscle |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | x | 
| Hypertonia |  |  |  |  |  | x |  |  | x | x | x | x | x | x |  |  |  |  |  |  | x |  | 
| Hypotonia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Muscle spasticity |  |  |  |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  | 
| Myopathy |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Musculoskeletal disorder |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Myocardial infarction |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  |  | 
| Myoclonus |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Nephritis interstitial |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Neurosis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Pain in extremity |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Pancreatitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x |  | 
| Pelvic pain |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Pharyngitis |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x | x | 
| Phlebitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Pneumonia |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x | x | x | x |  | 
| Polyuria |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Prostatic disorder |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Purpura |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Rectal disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Rhinitis |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x | x | 
| Sciatica |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Sneezing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  |  | 
| Muscle spasms |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Withdrawal syndrome |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Suicide |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Thirst |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Tongue disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Tooth disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Toothache |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Vasodilation |  |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  | x |  | 
| Yawning |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  |  | 
| Urogenital disorder |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Peripheral vascular disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Essential hypertension |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Encephalopathy |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Chills |  |  |  |  |  |  |  | x |  |  |  |  |  | x |  |  |  |  |  |  | x |  | 
| Oedema peripheral |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x | x | 
| Hypophosphataemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Pyelonephritis chronic |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Withdrawal symptom |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Acute sinusitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Acute bronchitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Amylase increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Creatinine increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Crystalluria calcium |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Neutrophil count increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Accidental injury |  |  |  |  |  | x |  |  | x | x | x | x | x | x |  |  |  |  |  |  | x |  | 
| Lactic dehydrogenase activity increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Muscular weakness |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Phosphatase alkaline increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Tendon disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Drug withdrawal syndrome |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  |  | 
| Abnormal faeces |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Muscle twitching |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x | x | x |  |  | 
| Tachypnoea |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Cutis anserina |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Increased appetite |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Disorientation |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  |  | 
| Tension |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Thinking abnormal |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x |  | 
| Speech impairment NOS |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Derealisation |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Abnormal dreams |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x |  | 
| Visual acuity reduced |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Cerebration impaired |  |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  |  |  | 
| Upset stomach |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Peripheral ischaemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  |  | 
| Vein pain |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Urine abnormality |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x |  | 
| Parkinsonism aggravated |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Menopausal symptoms |  |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  |  |  | 
| Edema of lower extremities |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  |  | 
| Throat sore |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  |  | 
| Gastroduodenitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Eustachian tube disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Blood bilirubin increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Cognitive impairment |  |  |  |  |  | x |  |  | x | x | x | x | x |  |  |  |  |  |  |  |  |  | 
| Extrasystoles |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Effusion of knee |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Photosensitivity |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Sticky skin |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  |  | 
| Gastric irritation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Platelet count decreased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Prostatomegaly |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Coordination abnormal |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Stress symptoms |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Duodenal ulcer aggravated |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Coronary artery insufficiency |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Feeling jittery |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  |  | 
| Dizziness aggravated |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  |  | 
| Gastritis aggravated |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Asthma aggravated |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Potassium abnormal NOS |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Monocyte count increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Ca++ increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| White blood cells urine positive |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Cough increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Blood sodium increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Drug interaction |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dyssomnia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hyperuricaemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Thrombocytosis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Sleep disorder |  |  |  |  |  | x |  |  | x | x | x | x | x |  | x | x | x | x | x | x |  | x | 
| Paraesthesia NEC |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Blood creatine phosphokinase increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  |  | 
| Arthropod bite |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Blood cholesterol abnormal |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Blood potassium increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Blood potassium decreased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Lymphocyte count decreased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Urea increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Pharyngolaryngeal pain |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Food aversion |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Peripheral swelling |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  |  | 
| Hypersomnia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Band neutrophil count increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Photodermatosis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Ischaemic stroke |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Analgesic effect |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Genitourinary tract infection |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Abdominal bloating |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Paranoia |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Thrombophlebitis superficial |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Sore mouth |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Uric acid increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Eosinophil count increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Abnormal ejaculation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Feeling hot |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  |  | 
| Vaginal haemorrhage |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Abnormal vision |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Blood calcium decreased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |