| Side effect | Data for drug | Placebo | Labels | 
|  | 1 | 2 | 3 | 4 | 5 | 6 | 
| Blood urea increased | 9% | 7.6% | x |  |  | x | x | x | 
| Dyspepsia | 6.4% | 6% | x |  |  | x | x | x | 
| Syncope | 5.9% | 3.3% | x |  | x | x | x | x | 
| Hyperkalaemia | 5.3% | 2.8% | x | x | x | x | x |  | 
| Hypocalcaemia | 4.7% | 3.9% |  |  |  | x | x |  | 
| Creatinine increased | 4.7% | 2.4% | x |  |  | x | x |  | 
| Myalgia | postmarketing, 4.7% | 3.1% |  | x | x | x | x | x | 
| Bradycardia | postmarketing, 4.7% | 4.4% | x | x | x | x | x | x | 
| Gastritis | 4.2% | 3.6% |  |  |  | x | x | x | 
| Cough | 2.6% - 35% | 0.9% - 22% | x | x |  | x | x | x | 
| Intermittent claudication | 3.8% | 2% |  |  |  | x | x |  | 
| Cardiogenic shock | 3.8% | 2% |  |  |  | x | x |  | 
| Cerebrovascular accident | 3.3% | 3.2% |  |  |  | x | x | x | 
| Mediastinal disorder | postmarketing, 2.6% - 3.9% | 0.9% - 2.6% |  | x | x | x | x | x | 
| Headache | 2.3% - 4.9% | 0.5% | x | x |  | x | x | x | 
| Asthenia | 2.01% - 3.3% | 2.01% - 2.6% |  | x |  | x | x | x | 
| Angiopathy | postmarketing, 2.1% | 0.6% |  | x | x | x | x | x | 
| Dizziness | 1.7% - 23% | 1.4% - 17% | x | x |  | x | x | x | 
| Nervous system disorder | postmarketing, 1.9% - 2.31% | 0.5% - 1.4% |  | x | x | x | x | x | 
| Upper respiratory tract infection | 0.2% - 3.4% |  | x |  |  | x | x | x | 
| Hypotension | 0.5% - 11% | 0.6% - 6.8% | x | x | x | x | x | x | 
| Gastrointestinal disorder | postmarketing, 1.15% | 0% |  | x | x | x | x | x | 
| Urinary tract infection | 0% - 1.5% |  |  |  |  | x | x | x | 
| Palpitations | 0.7% |  | x | x | x | x | x | x | 
| Rhinitis | 0% - 1.4% |  |  |  |  | x | x |  | 
| Gastrointestinal pain | 0.1% - 1.2% |  |  |  |  | x | x | x | 
| Nausea | postmarketing, 0.5% - 1.15% | 0% |  | x | x | x | x | x | 
| Pruritus | postmarketing, 0.5% |  | x | x | x | x | x | x | 
| Malaise | 0.5% - 1.1% |  |  | x |  | x | x | x | 
| Rash | postmarketing, 0.4% - 1.2% |  | x | x | x | x | x | x | 
| Bronchitis | postmarketing, 0.3% - 3.9% |  |  | x | x | x | x | x | 
| Diarrhoea | postmarketing, 0.2% - 1.1% |  | x | x | x | x | x | x | 
| Abdominal pain | postmarketing |  | x | x | x | x | x | x | 
| Agranulocytosis | postmarketing |  |  | x | x | x | x |  | 
| Alopecia | postmarketing |  |  | x | x | x | x | x | 
| Angina pectoris | postmarketing |  |  | x | x | x | x | x | 
| Angioedema | postmarketing |  |  | x | x | x | x | x | 
| Transient ischaemic attack | postmarketing |  |  | x | x | x | x |  | 
| Infection | postmarketing |  |  | x | x | x | x | x | 
| Connective tissue disorder | postmarketing |  |  | x | x | x | x | x | 
| Dyspnoea | postmarketing |  | x | x | x | x | x | x | 
| Toxic epidermal necrolysis | postmarketing |  |  | x | x | x | x |  | 
| Erythema multiforme | postmarketing |  |  | x | x | x | x |  | 
| Body temperature increased | postmarketing |  |  | x | x | x | x | x | 
| Cardiac arrest | postmarketing |  |  | x | x | x | x |  | 
| Cardiac disorder | postmarketing |  |  |  | x |  |  |  | 
| Hypersensitivity | postmarketing |  |  | x | x | x | x | x | 
| Immune system disorder | postmarketing |  |  | x | x | x | x | x | 
| Leukopenia | postmarketing |  |  | x | x | x | x | x | 
| Myocardial infarction | postmarketing |  |  |  | x |  |  |  | 
| Pancreatitis | postmarketing |  | x | x | x | x | x | x | 
| Pancytopenia | postmarketing |  |  | x | x | x | x |  | 
| Stevens-Johnson syndrome | postmarketing |  |  | x | x | x | x |  | 
| Sweating | postmarketing |  |  | x | x | x | x |  | 
| Tachycardia | postmarketing |  |  | x | x | x | x | x | 
| Vomiting | postmarketing |  | x | x | x | x | x | x | 
| Dry mouth | postmarketing |  |  | x | x | x | x | x | 
| Haemoglobin decreased | postmarketing |  |  | x | x | x | x |  | 
| Unspecified disorder of skin and subcutaneous tissue | postmarketing |  |  | x | x | x | x |  | 
| Hepatic enzyme increased | postmarketing |  | x | x | x | x | x |  | 
| Platelet count decreased | postmarketing |  |  | x | x |  |  | x | 
| Haematocrit decreased | postmarketing |  |  | x | x | x | x |  | 
| Infestation NOS | postmarketing |  |  | x | x | x | x | x | 
| Blood and lymphatic system disorders | postmarketing |  |  | x | x | x | x |  | 
| Cerebral haemorrhage | postmarketing |  |  | x | x | x | x |  | 
| Abdominal distension |  |  | x |  |  |  |  |  | 
| Anaemia |  |  |  |  |  |  |  | x | 
| Haemolytic anaemia |  |  |  |  | x | x | x |  | 
| Anorexia |  |  |  |  |  |  |  | x | 
| Anxiety |  |  | x |  |  |  |  | x | 
| Arrhythmia |  |  |  |  | x | x | x |  | 
| Arthralgia |  |  |  |  | x | x | x | x | 
| Arthritis |  |  |  |  |  |  |  | x | 
| Atrial flutter |  |  |  |  |  |  |  | x | 
| Atrioventricular block |  |  |  | x |  | x | x |  | 
| Back pain |  |  |  |  |  |  |  | x | 
| Mental disorder |  |  |  |  |  |  |  | x | 
| Blepharitis |  |  |  |  |  |  |  | x | 
| Platelet disorder |  |  |  |  |  |  |  | x | 
| Breast disorder |  |  |  |  |  |  |  | x | 
| Chest pain |  |  | x |  | x | x | x | x | 
| Constipation |  |  | x |  | x | x | x | x | 
| Libido decreased |  |  | x |  | x | x | x | x | 
| Depression |  |  |  |  | x |  |  |  | 
| Drowsiness |  |  | x |  |  |  |  |  | 
| Dysgeusia |  |  |  |  |  |  |  | x | 
| Eczema |  |  |  |  |  |  |  | x | 
| Oedema |  |  | x |  |  |  |  | x | 
| Eosinophilia |  |  |  |  | x | x | x | x | 
| Epistaxis |  |  | x |  |  |  |  | x | 
| Eye disorder |  |  |  |  |  |  |  | x | 
| Fatigue |  |  | x |  |  |  |  | x | 
| Flatulence |  |  |  |  |  |  |  | x | 
| Flushing |  |  | x |  |  |  |  |  | 
| Gout |  |  | x |  | x | x | x | x | 
| Hallucination |  |  |  |  |  |  |  | x | 
| Cardiac failure |  |  |  |  | x | x | x |  | 
| Haematemesis |  |  |  |  |  |  |  | x | 
| Hepatitis |  |  |  |  | x | x | x | x | 
| Hypercholesterolaemia |  |  |  |  |  |  |  | x | 
| Hyperglycaemia |  |  |  |  |  |  |  | x | 
| Hyperhidrosis |  |  |  |  |  |  |  | x | 
| Hyperlipidaemia |  |  |  |  |  |  |  | x | 
| Hyponatraemia |  |  | x |  |  |  |  | x | 
| Ichthyosis |  |  |  |  |  |  |  | x | 
| Infarction |  |  |  |  |  |  |  | x | 
| Jaundice cholestatic |  |  |  |  | x | x | x |  | 
| Renal failure acute |  |  |  |  | x |  | x |  | 
| Laryngeal oedema |  |  | x |  |  |  |  |  | 
| Leukocytosis |  |  |  |  |  |  |  | x | 
| Cramp muscle |  |  | x |  | x | x | x |  | 
| Myoclonus |  |  |  |  |  |  |  | x | 
| Neutropenia |  |  |  | x |  |  |  |  | 
| Osteoarthritis |  |  |  |  |  |  |  | x | 
| Pain in extremity |  |  | x |  |  |  |  | x | 
| Paraesthesia |  |  | x |  | x | x | x | x | 
| Pemphigus |  |  | x |  |  |  |  |  | 
| Pharyngitis |  |  | x |  |  |  |  | x | 
| Polyuria |  |  |  |  |  |  |  | x | 
| Psoriasis |  |  |  |  | x | x | x | x | 
| Pulmonary eosinophilia |  |  | x |  |  |  |  |  | 
| Renal failure |  |  |  |  |  | x |  | x | 
| Skin disorder |  |  |  |  | x | x | x | x | 
| Muscle spasms |  |  |  |  |  |  |  | x | 
| Thrombocytopenia |  |  | x |  |  |  |  |  | 
| Tinnitus |  |  |  |  |  |  |  | x | 
| Pollakiuria |  |  |  |  |  |  |  | x | 
| Urinary tract disorder |  |  |  |  |  |  |  | x | 
| Urticaria |  |  |  |  | x | x | x |  | 
| Varicose vein |  |  |  |  |  |  |  | x | 
| Vasculitis |  |  |  |  |  |  |  | x | 
| Ventricular tachycardia |  |  |  |  |  |  |  | x | 
| Vertigo |  |  | x |  |  |  |  | x | 
| Peripheral vascular disorder |  |  |  |  |  |  |  | x | 
| Atrioventricular block first degree |  |  | x |  |  |  |  |  | 
| Agitation |  |  |  |  |  |  |  | x | 
| Apathy |  |  |  |  |  |  |  | x | 
| Oedema peripheral |  |  |  |  |  |  |  | x | 
| Migraine |  |  |  |  |  |  |  | x | 
| Antinuclear antibody positive |  |  |  |  |  |  |  | x | 
| Conjunctival oedema |  |  |  |  |  |  |  | x | 
| Enzyme abnormality |  |  |  |  |  |  |  | x | 
| Red blood cell sedimentation rate increased |  |  |  |  |  |  |  | x | 
| Myocardial ischaemia |  |  |  |  |  |  |  | x | 
| Liver function test abnormal |  |  |  |  |  |  |  | x | 
| Bone pain |  |  |  |  |  |  |  | x | 
| Alanine aminotransferase increased |  |  | x |  |  |  |  |  | 
| Dry skin |  |  |  |  |  |  |  | x | 
| Malnutrition |  |  |  |  |  | x | x |  | 
| Blood creatinine increased |  |  |  |  |  |  |  | x | 
| Productive cough |  |  |  |  |  |  |  | x | 
| Erectile dysfunction |  |  | x |  | x | x | x | x | 
| Azotaemia |  |  |  |  |  |  |  | x | 
| Congenital arterial malformation |  |  |  |  |  |  |  | x | 
| Hepatobiliary disease |  |  |  |  |  |  |  | x | 
| Migraine without aura |  |  |  |  |  |  |  | x | 
| Photosensitivity |  |  |  |  |  |  |  | x | 
| Serum creatinine decreased |  |  |  |  |  | x | x |  | 
| Arrhythmia supraventricular |  |  |  |  |  |  |  | x | 
| Laboratory test abnormal |  |  |  |  |  |  |  | x | 
| Transaminases increased |  |  |  |  |  |  |  | x | 
| Electrocardiogram abnormal |  |  |  |  |  |  |  | x | 
| Visual disturbance |  |  |  |  |  |  |  | x | 
| Hot flush |  |  |  |  |  |  |  | x | 
| Presyncope |  |  | x |  |  |  |  |  | 
| Hyperuricaemia |  |  |  |  |  |  |  | x | 
| White blood cell count decreased |  |  | x |  |  |  |  |  | 
| Ear and labyrinth disorders |  |  |  |  |  |  |  | x | 
| Sleep disorder |  |  |  |  |  |  |  | x | 
| Blood alkaline phosphatase increased |  |  |  |  |  |  |  | x | 
| Potassium increased |  |  | x |  |  |  |  |  | 
| Pharyngolaryngeal pain |  |  |  |  |  |  |  | x | 
| Hypotension symptomatic |  |  | x |  |  |  |  |  | 
| Upper respiratory tract inflammation |  |  |  |  |  |  |  | x | 
| Insomnia |  |  | x |  | x | x | x | x | 
| Upper respiratory tract congestion |  |  |  |  |  |  |  | x | 
| Ileus |  |  |  |  | x | x | x |  | 
| Feeling abnormal |  |  |  |  | x | x | x | x | 
| Somnolence |  |  |  |  | x | x | x | x |