Exemestane
Side effects
Options:
Show MedDRA Preferred Terms
Side effect
|
Data for drug
|
Placebo
|
Labels
|
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
|
10
|
11
|
Arthralgia
|
very common, 8.6% - 28.8%
|
28.8%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Alopecia
|
common, 2-5% - 15.1%
|
4.1%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Arthritis
|
very common
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Fatigue
|
very common, 7.5% - 29%
|
19.2%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Musculoskeletal pain
|
very common
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Joint stiffness
|
very common
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Hot flush
|
very common, 5% - 32.9%
|
24.7%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Pain
|
common, 2.8% - 13%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Sweating
|
6-19%
|
|
|
|
|
|
x
|
|
|
|
|
|
|
Nausea
|
very common, 5% - 18%
|
16.4%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Cardiovascular disorder
|
10.6% - 12.8%
|
|
|
x
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Cardiac disorder
|
10.6% - 12.8%
|
|
|
x
|
|
|
|
|
|
|
|
|
|
Abdominal pain
|
common, 2.8% - 11%
|
13.7%
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
Insomnia
|
very common, 3.3% - 11-20%
|
15.1%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Sweating increased
|
common — 4.5% - 17.8%
|
20.6%
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Anxiety
|
4.1% - 11%
|
5.5%
|
|
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
Dyspnoea
|
0.3% - 15%
|
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
Depression
|
common, 5.6% - 13%
|
6.9%
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
Pain in extremity
|
very common, 6.4% - 9%
|
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Hypertension
|
1.7% - 15.1%
|
6.9%
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
Dermatitis
|
8.2%
|
1.4%
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Dizziness
|
common, 3% - 8-13%
|
9.6%
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
Headache
|
very common, 1.5% - 8-19%
|
4.1%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Back pain
|
very common, 2-5% - 8.6%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Oedema peripheral
|
6% - 7%
|
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
Asthenia
|
6%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Cough
|
6% - 7%
|
|
|
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
Oedema
|
2-5% - 7%
|
6.9%
|
|
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
Leg edema
|
common, 1.4% - 7%
|
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
Influenza-like symptoms
|
5% - 6%
|
|
|
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
Osteoarthritis
|
very common, 4.5% - 5.9%
|
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Weight increased
|
5.5% - 8%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Myalgia
|
very common, 5.5% - 2-33%
|
4.1%
|
x
|
x
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
Anorexia
|
common, 5% - 6%
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
Carpal tunnel syndrome
|
common
|
|
x
|
x
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Constipation
|
common, 0.8% - 8%
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
Diarrhoea
|
common, 4% - 9.6%
|
1.4%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Dyspepsia
|
common, 2-5%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Body temperature increased
|
5%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Fracture
|
common
|
|
x
|
x
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Gastrointestinal disorder
|
common
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Hoarseness
|
5%
|
|
|
|
|
|
x
|
|
|
|
|
|
|
Hypertrichosis
|
5%
|
|
|
|
|
|
x
|
|
|
|
|
|
|
Osteoporosis
|
common, 7%
|
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Vomiting
|
common, 0.8% - 7%
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
Visual disturbance
|
3.8% - 7%
|
|
|
x
|
|
|
x
|
|
|
x
|
x
|
x
|
x
|
Bronchitis
|
2-5%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Chest pain
|
2-5%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Infection
|
2-5%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Confusional state
|
2-5%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Rash
|
common, 0% - 2-5%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Lymphoedema
|
2-5%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Pharyngitis
|
2-5%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Rhinitis
|
2-5%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Sinusitis
|
2-5%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Upper respiratory tract infection
|
2-5%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Urinary tract infection
|
2-5%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Bone pain
|
2-5%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Cramp muscle
|
3%
|
|
x
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Increased appetite
|
2.8% - 6%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Vaginal haemorrhage
|
0.6% - 4%
|
|
x
|
x
|
|
|
x
|
|
x
|
|
|
|
|
Hepatitis
|
postmarketing
|
|
x
|
x
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
Hypersensitivity
|
postmarketing
|
|
x
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
Immune system disorder
|
postmarketing
|
|
x
|
x
|
|
|
|
x
|
|
|
|
|
x
|
Nervous system disorder
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Paraesthesia
|
postmarketing
|
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Pruritus
|
postmarketing, 2-5%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Urticaria
|
postmarketing
|
|
x
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
Hepatitis cholestatic
|
postmarketing
|
|
x
|
x
|
|
|
|
x
|
|
|
x
|
x
|
x
|
Unspecified disorder of skin and subcutaneous tissue
|
postmarketing
|
|
x
|
x
|
|
|
|
x
|
|
|
|
|
x
|
Hepatobiliary disease
|
postmarketing
|
|
x
|
x
|
|
|
|
x
|
|
|
|
|
x
|
Acute generalised exanthematous pustulosis
|
postmarketing
|
|
|
|
|
|
|
x
|
|
|
|
x
|
x
|
Angina pectoris
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Mental disorder
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Bone disorder
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Neoplasm malignant
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Endometrial hyperplasia
|
|
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Erythema multiforme
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Genital disorder female
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Cardiac failure
|
|
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Haemorrhage
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
Hypercholesterolaemia
|
|
|
x
|
|
|
|
|
|
x
|
|
|
|
|
Hypoaesthesia
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Leukopenia
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
Multi-organ failure
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Musculoskeletal disorder
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Myocardial infarction
|
|
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Neoplasm
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Opportunistic infection
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
Osteochondrosis
|
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
Polyp
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Pulmonary embolism
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Gastric ulcer
|
|
|
x
|
x
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
Cerebrovascular accident
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Tendonitis
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Thrombocytopenia
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
Thromboembolism
|
|
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Viral infection
|
|
|
|
x
|
|
|
x
|
|
|
|
|
|
|
Deep vein thrombosis
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Myocardial ischaemia
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Uterine polyp
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
Trigger finger
|
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
Sickness
|
|
|
x
|
x
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Vaginal dryness
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
Neuropathy
|
|
|
x
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Osteoporotic fracture
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Hepatic impairment
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
Coronary artery disease
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Indications
Information about indications was extracted from the indications and usage sections of the labels.
Side effects: | 54 |
Source: | medicines.org.au |
---|
Side effects: | 54 |
Source: | Medsafe |
---|
Side effects: | 48 |
Source: | FDA |
---|
Side effects: | 48 |
Source: | FDA |
---|
Side effects: | 53 |
Source: | BC Cancer |
---|
Side effects: | 65 |
Source: | FDA Structured Product Label |
---|
Side effects: | 80 |
Source: | Health Canada |
---|
Side effects: | 74 |
Source: | FDA |
---|
Side effects: | 78 |
Source: | FDA Structured Product Label |
---|
Side effects: | 81 |
Source: | FDA Structured Product Label |
---|
Side effects: | 84 |
Source: | FDA Structured Product Label |
---|
Color scheme:
standard – alternative
|
|
100%
|
|
|
75%
|
|
|
50%
|
|
|
10%
|
|
|
frequent (1% to 100%)
|
|
|
infrequent (0.1% to 1%)
|
|
|
rare (<0.1%)
|
|
|
postmarketing
|
|
|
0%
|
|
|
no frequency information
|
|
|
not found on label
|