Guillain-Barre syndrome

Definition: An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)

Synonyms (terms occurring on more labels are shown first): Guillain-Barre syndrome, Guillain Barre syndrome, Guillain- Barre Syndrome, Guillain_Barre syndrome, ascending paralysis

More information: PubMed search and possibly Wikipedia