Pimozide
Side effects
Options:
Hide MedDRA Preferred Terms
MedDRA Preferred Term
|
Side effect
|
Data for drug
|
Placebo
|
Labels
|
|
1
|
2
|
Asthenia
|
Asthenia
|
13.9% - 25%
|
|
|
x
|
Akinesia
|
Akinesia
|
8%
|
0%
|
|
x
|
Somnolence
|
Drowsiness
|
7%
|
3%
|
|
x
|
Somnolence
|
postmarketing, 25% - 27.8%
|
|
x
|
x
|
Agitation
|
Hyperkinesia
|
2.78% - 5.56%
|
|
|
x
|
Excitement
|
0%
|
1%
|
|
x
|
Hyperkinesia
|
Hyperkinesia
|
2.78% - 5.56%
|
|
|
x
|
Visual impairment
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Visual disturbance
|
2.78% - 5.56%
|
0%
|
|
x
|
Spots before eyes
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0%
|
1%
|
|
x
|
Muscle tightness
|
Muscle tightness
|
3%
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0%
|
|
x
|
Dysphagia
|
Dysphagia
|
2.78%
|
|
|
x
|
Torticollis
|
Torticollis
|
2.78%
|
|
|
x
|
Myalgia
|
Myalgia
|
2.78%
|
|
|
x
|
Musculoskeletal discomfort
|
Myalgia
|
2.78%
|
|
|
x
|
Abnormal dreams
|
Abnormal dreams
|
2.78%
|
|
|
x
|
Electrocardiogram abnormal
|
Electrocardiogram abnormal
|
2.78%
|
|
|
x
|
Depression
|
Depression
|
2%
|
3%
|
|
x
|
Speech disorder
|
Speech disorder
|
2%
|
0%
|
|
x
|
Diarrhoea
|
Diarrhoea
|
1%
|
0%
|
|
x
|
Increased appetite
|
Increased appetite
|
1%
|
0%
|
|
x
|
Agranulocytosis
|
Agranulocytosis
|
postmarketing
|
|
x
|
|
Amenorrhoea
|
Amenorrhoea
|
postmarketing
|
|
x
|
|
Anaemia
|
Anaemia
|
postmarketing
|
|
x
|
|
Aplastic anaemia
|
Aplastic anaemia
|
postmarketing
|
|
x
|
|
Haemolytic anaemia
|
Haemolytic anaemia
|
postmarketing
|
|
|
x
|
Mental disorder
|
Mental disorder
|
postmarketing
|
|
x
|
|
Breast disorder
|
Breast disorder
|
postmarketing
|
|
x
|
|
Connective tissue disorder
|
Connective tissue disorder
|
postmarketing
|
|
x
|
|
Constipation
|
Constipation
|
postmarketing, 4%
|
2%
|
x
|
x
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Dizziness
|
Dizziness
|
postmarketing, 0%
|
1%
|
x
|
x
|
Syncope
|
|
|
|
x
|
Endocrine disorder
|
Endocrine disorder
|
postmarketing
|
|
x
|
|
Eosinophilia
|
Eosinophilia
|
postmarketing
|
|
x
|
|
Grand mal convulsion
|
Grand mal convulsion
|
postmarketing
|
|
x
|
|
Tonic-clonic seizures
|
|
|
|
x
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Dermatitis
|
Rash
|
postmarketing, 2.78% - 8.33%
|
|
x
|
x
|
Rash
|
Rash
|
postmarketing, 2.78% - 8.33%
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|
x
|
x
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Extrapyramidal disorder
|
Extrapyramidal disorder
|
postmarketing
|
|
x
|
|
Extrapyramidal symptoms
|
|
|
|
x
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Eye disorder
|
Eye disorder
|
postmarketing
|
|
x
|
|
Faecal incontinence
|
Faecal incontinence
|
postmarketing
|
|
x
|
|
Gastrointestinal disorder
|
Gastrointestinal disorder
|
postmarketing
|
|
x
|
|
Gingival hyperplasia
|
Gingival hyperplasia
|
postmarketing
|
|
|
x
|
Gynaecomastia
|
Gynaecomastia
|
postmarketing
|
|
x
|
|
Headache
|
Headache
|
postmarketing, 1% - 22.2%
|
2%
|
x
|
x
|
Cardiac disorder
|
Cardiac disorder
|
postmarketing
|
|
x
|
|
Blood disorder
|
Blood disorder
|
postmarketing
|
|
x
|
|
Hyperhidrosis
|
Hyperhidrosis
|
postmarketing
|
|
x
|
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Sweating
|
|
|
|
x
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Hyperprolactinaemia
|
Hyperprolactinaemia
|
postmarketing
|
|
x
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Hyponatraemia
|
Hyponatraemia
|
postmarketing
|
|
|
x
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Body temperature decreased
|
Body temperature decreased
|
postmarketing
|
|
x
|
|
Hypothermia
|
Body temperature decreased
|
postmarketing
|
|
x
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Leukopenia
|
Leukopenia
|
postmarketing
|
|
x
|
|
Muscle rigidity
|
Muscle rigidity
|
postmarketing, 2%
|
0%
|
x
|
x
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Nervous system disorder
|
Nervous system disorder
|
postmarketing
|
|
x
|
|
Neuroleptic malignant syndrome
|
Neuroleptic malignant syndrome
|
postmarketing
|
|
x
|
x
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Pancytopenia
|
Pancytopenia
|
postmarketing
|
|
x
|
|
Pruritus
|
Pruritus
|
postmarketing
|
|
x
|
|
Convulsion
|
Convulsion
|
postmarketing
|
|
|
x
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Salivary hypersecretion
|
Salivary hypersecretion
|
postmarketing, 5.56% - 13.9%
|
|
x
|
x
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Torsade de pointes
|
Torsade de pointes
|
postmarketing
|
|
x
|
|
Tremor
|
Tremor
|
postmarketing, 2.78%
|
|
x
|
x
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Urticaria
|
Urticaria
|
postmarketing
|
|
x
|
|
Ventricular fibrillation
|
Ventricular fibrillation
|
postmarketing
|
|
x
|
|
Ventricular tachycardia
|
Ventricular tachycardia
|
postmarketing
|
|
x
|
|
Dry mouth
|
Dry mouth
|
postmarketing, 5%
|
1%
|
x
|
x
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Urinary retention
|
Urinary retention
|
postmarketing
|
|
x
|
|
Cogwheel rigidity
|
Cogwheel rigidity
|
postmarketing
|
|
x
|
|
Electroencephalogram abnormal
|
Electroencephalogram abnormal
|
postmarketing
|
|
x
|
|
Electrocardiogram QT prolonged
|
Electrocardiogram QT prolonged
|
postmarketing
|
|
x
|
|
Skin disorder
|
Unspecified disorder of skin and subcutaneous tissue
|
postmarketing
|
|
x
|
|
Bradykinesia
|
Bradykinesia
|
postmarketing
|
|
x
|
|
Galactorrhoea
|
Galactorrhoea
|
postmarketing
|
|
x
|
|
Erectile dysfunction
|
Erectile dysfunction
|
postmarketing, 3%
|
0%
|
x
|
x
|
Vision blurred
|
Vision blurred
|
postmarketing
|
|
x
|
x
|
Akathisia
|
Akathisia
|
postmarketing, 8%
|
0%
|
x
|
x
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Motor restlessness
|
|
|
|
x
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Tardive dyskinesia
|
Tardive dyskinesia
|
postmarketing
|
|
x
|
x
|
Thrombocytopenic purpura
|
Thrombocytopenic purpura
|
postmarketing
|
|
x
|
|
Insomnia
|
Insomnia
|
postmarketing, 2%
|
2%
|
x
|
x
|
Oculogyric crisis
|
Oculogyration
|
postmarketing
|
|
x
|
|
Oculogyric crisis
|
|
|
|
x
|
Nuchal rigidity
|
Nuchal rigidity
|
postmarketing
|
|
x
|
|
Decreased appetite
|
Anorexia
|
|
|
|
x
|
Chest pain
|
Chest pain
|
|
|
|
x
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Dyskinesia
|
Dyskinesia
|
|
|
|
x
|
Movements involuntary
|
|
|
|
x
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Eructation
|
Eructation
|
0%
|
1%
|
|
x
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Hypertension
|
Hypertension
|
|
|
|
x
|
Hypotension
|
Hypotension
|
|
|
|
x
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Orthostatic hypotension
|
Orthostatic hypotension
|
|
|
|
x
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Menstrual disorder
|
Menstrual disorder
|
0%
|
1%
|
|
x
|
Muscle spasms
|
Cramp muscle
|
0%
|
1%
|
|
x
|
Nausea
|
Nausea
|
0%
|
2%
|
|
x
|
Nocturia
|
Nocturia
|
|
|
|
x
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Palpitations
|
Palpitations
|
|
|
|
x
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Abnormal behaviour
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Vermiculation
|
|
|
|
x
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Schizophrenia
|
Schizophrenia
|
|
|
|
x
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Shock
|
Syncope
|
|
|
|
x
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Syncope
|
Syncope
|
|
|
|
x
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Loss of consciousness
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Syncope
|
|
|
|
x
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Tachycardia
|
Tachycardia
|
|
|
|
x
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Pollakiuria
|
Pollakiuria
|
|
|
|
x
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Vomiting
|
Vomiting
|
0%
|
1%
|
|
x
|
Weight increased
|
Weight increased
|
|
|
|
x
|
Weight decreased
|
Weight decreased
|
|
|
|
x
|
Cataract
|
Cataract
|
|
|
|
x
|
Periorbital oedema
|
Periorbital oedema
|
|
|
|
x
|
Opisthotonus
|
Opisthotonus
|
|
|
|
x
|
Hyperreflexia
|
Hyperreflexia
|
|
|
|
x
|
Skin irritation
|
Skin irritation
|
|
|
|
x
|
Electrocardiogram U-wave abnormality
|
Electrocardiogram U wave present
|
|
|
|
x
|
Protrusion tongue
|
Protrusion tongue
|
|
|
|
x
|
Parkinsonism
|
Parkinsonism
|
|
|
|
x
|
Hyperpyrexia
|
Hyperpyrexia
|
|
|
|
x
|
Abdominal discomfort
|
Distress gastrointestinal
|
|
|
|
x
|
Electrocardiogram change
|
Electrocardiogram change
|
|
|
|
x
|
Loss of libido
|
Loss of libido
|
|
|
|
x
|
Indications
Information about indications was extracted from the indications and usage sections of the labels.
Side effects: | 53 |
Source: | Health Canada |
---|
Side effects: | 74 |
Source: | FDA Structured Product Label |
---|
Color scheme:
standard – alternative
|
|
100%
|
|
|
75%
|
|
|
50%
|
|
|
10%
|
|
|
frequent (1% to 100%)
|
|
|
infrequent (0.1% to 1%)
|
|
|
rare (<0.1%)
|
|
|
postmarketing
|
|
|
0%
|
|
|
no frequency information
|
|
|
not found on label
|