Acyclovir
  
Side effects 
	
		
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| Side effect | Data for drug | Placebo | Labels | 
|  | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 
| Superficial punctate keratopathy | very common |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Malaise | 11.1% - 11.5% | 11.1% |  |  |  |  |  |  |  | x |  | x | x |  |  | x |  |  |  |  |  | x | 
| Abdominal pain | common |  |  |  |  |  |  |  | x |  | x |  |  | x | x | x | x | x |  | x | x | x | 
| Conjunctivitis | common |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dizziness | common |  |  | x |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Fatigue | common |  |  |  |  |  |  |  |  |  | x |  |  | x | x | x | x | x |  | x | x | x | 
| Hallucination | very rare, common |  |  |  |  |  | x | x | x | x | x | x | x |  |  | x |  |  | x |  |  | x | 
| Vomiting | common, 2.5% - 8% | 2.5% |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Stinging | common |  | x |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Somnolence | very rare, common |  |  |  |  |  | x | x |  | x | x | x | x |  |  | x |  |  | x |  |  | x | 
| Nausea | common, 2.4% - 8% | 11.5% |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Body temperature increased | common, 4% |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | x | x | x | 
| Diarrhoea | postmarketing — 1.5% - 5% | 0.3% - 2.2% |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Headache | common, 0.9% - 5.9% | 11.1% |  | x |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Dehydration | 2% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | 
| Herpes simplex | 2% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | 
| Rhinorrhoea | 2% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | 
| Asthenia | 1.2% |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | 
| Paraesthesia | 0.8% - 1.2% |  |  |  |  |  |  |  |  | x |  | x | x |  |  | x |  |  | x |  |  |  | 
| Aggression | postmarketing |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | x | x | x | x |  | 
| Alopecia | postmarketing, uncommon |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Anaphylactic shock | postmarketing, rare |  |  |  |  | x | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Aplastic anaemia | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x |  | x | x |  | 
| Angioedema | very rare — rare |  |  |  | x | x | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Ataxia | very rare, postmarketing |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Blepharitis | rare |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Coma | very rare, postmarketing |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Confusional state | very rare — common |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Dermatitis contact | postmarketing |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dysarthria | very rare, postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x |  | x | x | x | 
| Dyspnoea | postmarketing, rare |  |  |  |  |  | x | x |  |  | x |  |  | x | x | x | x | x |  | x | x | x | 
| Eczema | postmarketing |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Erythema multiforme | postmarketing |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | 
| Rash | postmarketing — 1.3% - 1.7% |  |  |  |  |  |  |  |  |  | x |  |  |  | x |  | x | x |  | x | x | x | 
| Hepatitis | very rare, postmarketing |  |  |  |  |  | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Hypersensitivity | postmarketing |  |  |  |  |  | x | x |  |  |  |  |  | x | x | x | x | x |  | x | x |  | 
| Hypertension | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x |  | x | x |  | 
| Pruritus | postmarketing, common |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Psychotic disorder | very rare, postmarketing |  |  |  |  |  | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Renal failure | very rare, postmarketing |  |  |  |  |  |  |  |  | x | x | x | x | x | x |  | x | x | x | x | x | x | 
| Convulsion | very rare — common |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Tachycardia | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x |  | x | x |  | 
| Thrombocytopenia | very rare, postmarketing |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Tremor | very rare, postmarketing |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Urticaria | postmarketing, uncommon |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Encephalopathy | very rare, postmarketing |  |  |  |  |  |  |  |  | x | x |  | x | x | x | x | x | x | x | x | x | x | 
| Agitation | very rare, postmarketing |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Blood urea increased | rare |  |  |  |  |  | x | x |  | x | x | x | x |  |  |  |  |  | x |  |  | x | 
| Mania | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x |  | x | x |  | 
| Photosensitivity | postmarketing, common |  |  |  |  |  | x | x |  |  | x |  |  | x | x | x | x | x |  | x | x | x | 
| Face oedema | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x |  | x | x |  | 
| Depressed level of consciousness | postmarketing |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | x |  | x | x |  | 
| Renal pain | very rare, postmarketing |  |  |  |  |  |  |  |  |  | x | x |  | x | x |  | x | x |  | x | x | x | 
| Auditory and visual hallucinations | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x |  | x | x |  | 
| Leukocytoclastic vasculitis | postmarketing |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | x | x | x | x |  | 
| Anaemia | very rare |  |  |  |  |  | x | x | x | x | x | x | x |  |  | x |  |  | x |  |  | x | 
| Type I hypersensitivity | very rare |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Jaundice | very rare |  |  |  |  |  | x | x |  | x | x | x | x |  |  | x |  |  | x |  |  | x | 
| Renal failure acute | very rare |  |  |  |  |  | x | x |  |  | x |  |  | x |  | x | x | x |  | x | x | x | 
| Leukopenia | very rare |  |  |  |  |  | x | x |  | x | x | x | x |  |  | x |  |  | x |  |  | x | 
| Renal impairment | very rare |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x | 
| Anorexia |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x |  |  | x |  |  | x | 
| Anuria |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Arthralgia |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x |  | x | x | x | 
| Cardiac tamponade |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Chest pain |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Constipation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Delirium |  |  |  |  |  |  |  |  |  | x |  | x | x |  |  |  |  |  | x |  |  |  | 
| Disseminated intravascular coagulation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  | 
| Dysgeusia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Dysmenorrhoea |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x |  | x | x |  | 
| Oedema |  |  | x |  |  |  |  |  | x |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Toxic epidermal necrolysis |  |  |  |  |  |  |  |  |  | x |  | x | x |  |  | x |  |  | x |  |  |  | 
| Eye disorder |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Flatulence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | 
| Gastrointestinal disorder |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x | 
| Haematuria |  |  |  |  |  |  |  | x | x | x |  | x | x |  |  |  |  |  | x |  |  |  | 
| Haemolytic uraemic syndrome |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x |  | x | x |  | 
| Herpes NOS |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Hyperbilirubinaemia |  |  |  |  |  |  |  |  |  | x |  | x | x |  |  |  |  |  | x |  |  |  | 
| Hypokalaemia |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hypotension |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  | x |  |  |  | 
| Immune system disorder |  |  |  |  | x |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x | 
| Inflammation |  |  |  |  | x |  |  | x | x |  |  |  |  |  |  |  |  |  | x |  |  |  | 
| Irritability |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Ischaemia |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Leg pain |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Lethargy |  |  |  | x |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Leukocytosis |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | x |  |  |  | 
| Mediastinal disorder |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x | 
| Cramp muscle |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Nasopharyngitis |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x |  | x | x |  | 
| Necrosis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  | 
| Nervous system disorder |  |  |  | x |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x | 
| Neutropenia |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | x |  |  | x | 
| Palpitations |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Pars planitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Phlebitis |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Pulmonary oedema |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Thrombotic thrombocytopenic purpura |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | x | x |  | x | x |  | 
| Stevens-Johnson syndrome |  |  |  |  |  |  |  |  |  | x |  | x | x |  |  | x |  |  | x |  |  |  | 
| Aphthous stomatitis |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Thirst |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Erythema |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Upper respiratory tract infection |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x |  | x | x |  | 
| Urinary tract disorder |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x | 
| Vasculitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Vertigo |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Stupor |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  | x |  |  |  | 
| Oedema peripheral |  |  |  |  |  |  |  |  |  | x |  | x | x |  |  | x |  |  | x |  |  |  | 
| Purpura fulminans |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Application site reaction |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Creatinine increased |  |  |  |  |  |  |  |  |  | x |  | x | x |  |  | x |  |  | x |  |  |  | 
| Phosphatase alkaline increased |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x |  | x | x |  | 
| Aspartate aminotransferase increased |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x |  | x | x |  | 
| Alanine aminotransferase increased |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x |  | x | x |  | 
| Photosensitivity reaction |  |  |  |  |  |  |  |  |  | x |  | x | x |  |  |  |  |  | x |  |  |  | 
| Unspecified disorder of skin and subcutaneous tissue |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x | 
| Lightheadedness |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Myalgia |  |  |  |  |  |  |  |  |  | x |  | x | x |  |  | x |  |  | x |  |  |  | 
| Digestion impaired |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Ache |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Neurologic reaction |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Blood creatinine increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Haemoglobinaemia |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Skin exfoliation |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Gingival pain |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Skin burning sensation |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Throat sore |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Hepatobiliary disease |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x | 
| Platelet count decreased |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x |  | x | x |  | 
| Chapped lips |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Rigors |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Urine analysis abnormal |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Lymphadenopathy |  |  |  |  |  |  |  |  |  | x |  | x | x |  |  | x |  |  | x |  |  | x | 
| Application site irritation |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Application site pain |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Injection site phlebitis |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | x |  |  |  | 
| Distress gastrointestinal |  |  |  |  |  |  |  |  |  | x |  | x | x |  |  | x |  |  | x |  |  |  | 
| Lip dry |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Sweating increased |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Thrombocytosis |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | x |  |  |  | 
| Blood and lymphatic system disorders |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x | 
| Accelerated hair loss |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Thrombocytopenic purpura |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Raised liver function tests |  |  |  |  |  |  |  |  |  | x |  | x | x |  |  |  |  |  | x |  |  |  | 
| Insomnia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | 
| Sensitisation |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Thrombophlebitis superficial |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Neutrophilia |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | x |  |  |  | 
	 
 
  Indications
	Information about indications was extracted from the indications and usage sections of the labels.
	
 
	  
	  
		| Side effects: | 3 | 
|---|
		| Source: | FDA Structured Product Label | 
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		| Side effects: | 9 | 
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		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 9 | 
|---|
		| Source: | Medsafe | 
|---|
		 
	  
	  
		| Side effects: | 12 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 25 | 
|---|
		| Source: | Medsafe | 
|---|
		 
	  
	  
		| Side effects: | 31 | 
|---|
		| Source: | Medsafe | 
|---|
		 
	  
	  
		| Side effects: | 39 | 
|---|
		| Source: | Health Canada | 
|---|
		 
	  
	  
		| Side effects: | 45 | 
|---|
		| Source: | FDA | 
|---|
		 
	  
	  
		| Side effects: | 45 | 
|---|
		| Source: | Medsafe | 
|---|
		 
	  
	  
		| Side effects: | 46 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 47 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 49 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 49 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 50 | 
|---|
		| Source: | Health Canada | 
|---|
		 
	  
	  
		| Side effects: | 50 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 50 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 54 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 54 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 54 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 66 | 
|---|
		| Source: | medicines.org.au | 
|---|
		 
	  
  
 
  
	Color scheme:
	  
	  standard – alternative
	  
	
	
|  |  | 100% | 
|  |  | 75% | 
|  |  | 50% | 
|  |  | 10% | 
|  |  | frequent (1% to 100%) | 
|  |  | infrequent (0.1% to 1%) | 
|  |  | rare (<0.1%) | 
|  |  | postmarketing | 
|  |  | 0% | 
|  |  | no frequency information | 
|  |  | not found on label |