| Side effect | Data for drug | Placebo | Labels | 
|  | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 
| Pneumonia klebsiella | 40% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dysgeusia | common, 5% |  |  |  |  | x |  | x |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Ocular hyperaemia | common |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Corneal deposits | common |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Ocular discomfort | common |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Infusion site reactions | common |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Nasopharyngitis | 2.6% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Nausea | uncommon — 1.3% - 5.2% |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Fungal infection | 1.6% - 2.6% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Vaginal inflammation | 2% |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Micturition urgency | 2% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Sensation of foreign body | 1.8% - 2% |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Discomfort | 1.7% - 9.7% | 7.9% |  | x | x |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Diarrhoea | postmarketing — 1% - 2.3% |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Headache | uncommon, 1% - 3% |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Liver function test abnormal | 1.3% |  |  |  | x | x |  |  |  | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Hyperaemia | 1.2% | 1.4% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Erythema | 1.2% | 1.4% |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Redness | 1.2% | 1.4% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dizziness | rare — 1% - 2% |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Rash | postmarketing — 1% - 1.8% |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Vomiting | postmarketing — 1% - 2% |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Injection site pain | 1% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Pruritus | uncommon, 1.1% - 1.2% | 1.9% |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Eosinophilia | postmarketing — 0.6% |  |  |  |  | x | x |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | 
| Abdominal pain | rare, uncommon |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Anorexia | uncommon |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |  | x | 
| Eye pruritus | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Superinfection | uncommon |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Taste disorders | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Photophobia | uncommon |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Conjunctival oedema | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Eye pain | uncommon |  |  |  | x |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x |  | x | 
| Lacrimation increased | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Eyelid oedema | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Decreased appetite | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Visual acuity reduced | uncommon |  |  |  | x |  | x |  | x | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Keratopathy | uncommon |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Erythema of eyelid | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Eye swelling | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Blood bilirubin increased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Dry eye | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Eye discharge | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Corneal staining | uncommon |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Sleep disorder | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Corneal infiltrates | uncommon |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Foreign body sensation in eyes | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Eyelid margin crusting | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Renal impairment | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Eyelid exfoliation | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Leukopenia | postmarketing — 0.4% |  |  |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x |  | x | 
| Thrombocytopenia | postmarketing — uncommon |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Vertigo | postmarketing — uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Disorientation | postmarketing — uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dysaesthesia | postmarketing — uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hepatic impairment | postmarketing — uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Acidosis | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Agranulocytosis | very rare, postmarketing |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Albuminuria | postmarketing |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Anaphylactic shock | very rare — rare |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Anaemia | postmarketing, rare |  |  |  |  | x | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Haemolytic anaemia | very rare, postmarketing |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Angina pectoris | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Angioedema | postmarketing, rare |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Anosmia | postmarketing |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Anthrax | postmarketing |  |  |  |  |  |  |  |  |  |  | x |  | x | x |  |  | x |  | x |  |  | 
| Anxiety | postmarketing, rare |  |  |  |  | x |  | x | x |  |  |  |  |  |  |  | x |  |  |  | x | x | 
| Arrhythmia | postmarketing |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Arthralgia | postmarketing, uncommon |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Arthritis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Asthenia | postmarketing |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Asthenopia | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Ataxia | postmarketing |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Atrial flutter | postmarketing |  |  |  | x |  | x | x |  | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Blister | rare |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Bone disorder | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Bronchospasm | postmarketing |  |  |  | x |  | x | x |  | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Candida infection | postmarketing |  |  |  |  | x |  | x |  | x | x | x | x | x | x | x |  | x | x | x | x |  | 
| Vaginal moniliasis | postmarketing, 1% - 2% |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Confusional state | postmarketing — uncommon |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Conjunctivitis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Constipation | postmarketing |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x |  | x | 
| Corneal disorder | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dysphagia | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Delirium | postmarketing |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Dermatitis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dermatitis exfoliative | postmarketing, rare |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Diplopia | postmarketing, rare |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Drowsiness | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Dyspepsia | postmarketing — 1% |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Dyspnoea | postmarketing |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Ear pain | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Oedema | postmarketing — uncommon |  |  | x |  | x |  | x | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Endophthalmitis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Toxic epidermal necrolysis | very rare, postmarketing |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Grand mal convulsion | postmarketing |  |  |  | x | x |  |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Epistaxis | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Erythema multiforme | very rare, postmarketing |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Erythema nodosum | very rare, postmarketing |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Body temperature increased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Flatulence | postmarketing, uncommon |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |  | x | 
| Flushing | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Gastrointestinal haemorrhage | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Gout | postmarketing |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Gynaecomastia | postmarketing |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Hallucination | postmarketing — uncommon |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Cardiac disorder | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Cardiac murmur | postmarketing |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Haematuria | postmarketing — 1.2% |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Haemoptysis | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Haemorrhage | postmarketing |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Hepatitis | postmarketing, rare |  |  |  | x | x |  |  |  | x | x | x | x | x | x | x | x |  | x |  | x | x | 
| Hiccups | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Hordeolum | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hyperaesthesia | very rare, postmarketing |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Hyperglycaemia | rare |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Hyperhidrosis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hypersensitivity | postmarketing, rare |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Hypertension | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Hypoaesthesia | postmarketing, rare |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Hypoglycaemia | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Hypotension | postmarketing — uncommon |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Orthostatic hypotension | postmarketing |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Immune system disorder | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Intestinal perforation | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Jaundice | postmarketing — uncommon |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Jaundice cholestatic | postmarketing |  |  |  | x | x | x | x |  | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Keratitis | rare |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Calculus of kidney | postmarketing |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Lethargy | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Leukocytosis | postmarketing, rare |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Methaemoglobinaemia | postmarketing |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Cramp muscle | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hypertonia | postmarketing, rare |  |  |  |  | x |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Myasthenia gravis | very rare, postmarketing |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Myocardial infarction | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Myoclonus | postmarketing |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Nephritis | postmarketing |  |  |  | x |  | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Nephritis interstitial | postmarketing |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Nervous system disorder | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Neutropenia | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Nightmare | postmarketing |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Nystagmus | postmarketing |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Pain | postmarketing, uncommon |  |  |  | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Palpitations | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Pancreatitis | very rare — rare |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Pancytopenia | very rare — 0.1% |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Paraesthesia | postmarketing, rare |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Neuropathy peripheral | postmarketing |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x | x |  | 
| Petechiae | very rare — rare |  |  |  | x | x |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Phlebitis | postmarketing |  |  |  | x |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Pleural effusion | postmarketing |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Polyuria | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Psychotic disorder | very rare — rare |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Pulmonary embolism | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Purpura | postmarketing |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Renal failure | postmarketing — uncommon |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Rhinitis | rare |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Convulsion | postmarketing — uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Shock | postmarketing |  |  |  |  | x |  | x | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Status epilepticus | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  |  | 
| Stevens-Johnson syndrome | very rare — rare |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Sweating | postmarketing, rare |  |  |  | x | x |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Syncope | postmarketing, rare |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Tachycardia | postmarketing — uncommon |  |  |  | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Tendonitis | very rare, postmarketing |  |  |  |  | x | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Tinnitus | postmarketing, rare |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Torsade de pointes | postmarketing |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x |  | x | x | x | x |  | 
| Tremor | postmarketing, rare |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Tubulointerstitial nephritis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Uric acid level increased | postmarketing |  |  |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Urticaria | postmarketing — uncommon |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Uveitis | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Vaginal itching | postmarketing, 1% |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Vasculitis | very rare — rare |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Dry mouth | postmarketing |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | x |  |  |  | x | x | 
| Cerebral thrombosis | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Urinary retention | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Chills | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Hepatic failure | very rare, postmarketing |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Ventricular arrhythmia | postmarketing |  |  |  |  | x |  |  |  |  |  |  | x |  |  | x |  | x | x | x |  |  | 
| Agitation | postmarketing — 1.1% |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Photopsia | postmarketing |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Cystitis haemorrhagic | postmarketing |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Antibiotic associated colitis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Mouth ulceration | postmarketing |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Migraine | very rare — rare |  |  |  | x | x |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Amylase increased | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Crystalluria | postmarketing, rare |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Fixed eruption | postmarketing |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x | x | x | x | x |  | x | 
| Red blood cell sedimentation rate increased | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x |  |  |  |  | x | 
| Ventricular extrasystoles | postmarketing |  |  |  | x |  | x | x |  | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Manic psychosis | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Bone marrow depression | very rare — rare |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Hepatic necrosis | very rare — rare |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Aspartate aminotransferase increased | postmarketing |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Alanine aminotransferase increased | postmarketing |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Tendon rupture | very rare — rare |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Polyneuropathy | postmarketing |  |  |  |  |  |  |  |  |  |  |  | x |  |  | x |  | x | x | x |  |  | 
| Pneumonia anthrax | postmarketing |  |  |  |  |  |  |  |  |  |  | x |  | x | x |  |  | x |  | x |  |  | 
| Respiratory arrest | postmarketing |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Joint stiffness | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Photosensitivity reaction | rare |  |  |  |  | x |  | x |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Skin hyperpigmentation | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Unspecified disorder of skin and subcutaneous tissue | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Fatal outcomes | postmarketing, rare |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Lightheadedness | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Serum sickness-like reaction | very rare, postmarketing |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Malaise | postmarketing, uncommon |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Myalgia | postmarketing, rare |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Muscle twitching | postmarketing |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Abnormal dreams | rare |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Eye irritation | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Urethral haemorrhage | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Punctate keratitis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hepatobiliary disease | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Drug intolerance | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Eruption | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Epidermolysis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Vision blurred | postmarketing, uncommon |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Phobia | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Photosensitivity | postmarketing |  |  |  | x |  | x |  | x | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Platelet count decreased | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Candiduria | postmarketing |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Laboratory test abnormal | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Chromatopsia | postmarketing |  |  |  | x | x |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Respiratory distress | postmarketing |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Lymphadenopathy | postmarketing |  |  |  | x |  | x | x |  | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Visual disturbance | postmarketing — uncommon |  |  |  |  | x |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Serum potassium increased | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Gait disturbance | very rare, postmarketing |  |  |  | x |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Prothrombin time shortened | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Serum albumin decreased | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Blood glucose decreased | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Serum potassium decreased | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Serum calcium increased | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Cholesterol serum elevated | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Cardio-respiratory arrest | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Thrombocytosis | postmarketing, rare |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Allergic oedema | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Blood and lymphatic system disorders | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hypoaesthesia eye | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Corneal epithelium defect | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Prothrombin level abnormal | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Serum total protein decreased | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Blood monocytes increased | postmarketing |  |  |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Acute generalised exanthematous pustulosis | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  |  | 
| Insomnia | postmarketing |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Myasthenia | postmarketing |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Dysphasia | postmarketing |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Paranasal sinus hypersecretion | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Pseudomembranous colitis | postmarketing |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Ileus | postmarketing |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | x |  |  |  | x | x | 
| Ocular toxicity | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hearing impaired | very rare — uncommon |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Paranoia | postmarketing |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Phototoxicity | postmarketing |  |  |  | x |  |  |  |  | x | x | x | x |  | x | x |  | x | x | x |  |  | 
| Conjunctival hyperaemia | rare |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Ageusia | postmarketing |  |  |  |  | x | x | x |  | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Self injurious behaviour | very rare, rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  |  | 
| Suicidal ideation | very rare, rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  |  | 
| Completed suicide | very rare, rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  |  | 
| Benign intracranial hypertension | very rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Intracranial pressure increased | very rare, postmarketing |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Muscular weakness | very rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x |  |  | 
| Visual colour distortions | very rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Erythema multiforme minor | very rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Respiratory acidosis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Alopecia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Asthma |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Atrial fibrillation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Back pain |  |  |  |  | x | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x |  | x | 
| Mental disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Coagulopathy |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Breast disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Skin candida |  |  |  |  | x |  | x |  | x | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Oral candidiasis |  |  |  |  | x |  | x |  | x | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Cerebrovascular disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Chest pain |  |  |  |  | x | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x |  | x | 
| Colitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Connective tissue disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Corneal opacity |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Cystitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Depersonalisation |  |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x |  | x | 
| Depression |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Fungal skin infection |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Dysmenorrhoea |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dysuria |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  | x |  | 
| Oesophagitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Extravasation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Eye disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Fatigue |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Foot pain |  |  |  |  | x |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Gastritis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Gastrointestinal disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Glossitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Cardiac arrest |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Hemiplegia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Hepatomegaly |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Hyperbilirubinaemia |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Hypercalcaemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Hypercholesterolaemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Hypernatraemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Hyperventilation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Hypocalcaemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Kidney infection |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Inflammation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Irritable bowel syndrome |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Irritability |  |  |  |  | x |  | x |  | x | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Keratoconjunctivitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Renal failure acute |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Renal failure chronic |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Renal neoplasm |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Laryngeal oedema |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Leg pain |  |  |  |  | x |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Leukorrhea |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Liver disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Breast pain |  |  |  |  | x |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Mediastinal disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Megacolon toxic |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Melaena |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Meningism |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Metabolic disorder |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Muscle spasticity |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Necrosis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Nervousness |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x |  | x | 
| Neuritis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| NPN increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Nodule |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Otitis externa |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Pericarditis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Pharyngitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Polyneuritis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Prurigo |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Pruritus genital |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Pulmonary oedema |  |  |  |  | x |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x |  | x | 
| Repetitive strain injury |  |  |  |  | x |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Rhabdomyolysis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Septicemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Skin disorder |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Muscle spasms |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Stomatitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Ulcerative stomatitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Stridor |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Swelling |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Thirst |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Thrombophlebitis |  |  |  |  |  | x |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Tooth discolouration |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Typhoid fever |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Loss of consciousness |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Pollakiuria |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Urinary incontinence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Urinary tract disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Angiopathy |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Vasodilation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x | 
| Ventricular fibrillation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Ventricular tachycardia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Vaginitis bacterial |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Apathy |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Rash pustular |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Oedema peripheral |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Hepatic function abnormal |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Acute cystitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Creatinine renal clearance decreased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Creatinine increased |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Deafness transitory |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Tongue discolouration |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Tongue oedema |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Electrolyte abnormality |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Necrolysis epidermal |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Gamma-glutamyltransferase increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Impaired healing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Pulmonary haemorrhage |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Injection site reaction |  |  |  |  | x | x |  |  |  |  |  |  |  | x | x | x |  | x | x | x |  | x | 
| Accidental injury |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Kidney function abnormal |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Lactic dehydrogenase activity increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hepatocellular injury |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Bone pain |  |  |  |  | x |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Retrosternal pain |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Phosphatase alkaline increased |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Prothrombin level increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Vesiculobullous rash |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dry skin |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Renal vasculitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Joint swelling |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x |  |  |  | x |  | 
| Malnutrition |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Scab |  |  |  | x |  | x |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Ache wrists |  |  |  |  | x |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Disability |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Increased appetite |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Abdominal discomfort |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Epigastric pain |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Abdominal pain lower |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Rectal tenesmus |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Disturbance in attention |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Tenderness |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Trembling |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Swollen tongue |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Creatinine low |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Pain in arm |  |  |  |  | x |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Suprapubic pain |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Colour blindness |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Night cramps |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Ventricular bigeminy |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Chemosis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Urine odour abnormal |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Papule |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Anaphylactoid reaction |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Gastrointestinal candidiasis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Enlargement abdomen |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Vaginal infection |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Lacrimation |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Punctate epithelial erosion |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Rash maculo-papular |  |  |  |  |  | x |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Rigors |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Abdominal aortic bruit |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Bradycardia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Joint sprain |  |  |  |  | x |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Transaminases increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dementia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Coordination abnormal |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Application site pain |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Bad taste |  |  |  | x | x |  | x |  | x | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Face oedema |  |  |  |  | x |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Surgical intervention |  |  |  |  | x |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Lipase increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Prothrombin level decreased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Cough increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Nephropathy toxic |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Bladder infection |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hot flush |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Stinging |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Drug interaction |  |  |  |  | x |  | x |  | x | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Sweating increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Hyperuricaemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Convulsive seizure |  |  |  |  | x |  | x |  | x | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Ear pruritus |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Infestation NOS |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Ear and labyrinth disorders |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Bone and joint infections |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Skin haemorrhage |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| International normalised ratio decreased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| AGEP |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Chromosomal mutation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Nosocomial pneumonia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Medication residue |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Drug fever |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | 
| Parosmia |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Gout flare |  |  |  |  | x |  | x |  | x | x | x | x | x | x | x | x |  | x | x | x |  | x | 
| Tingling sensation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Cross resistance |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Somnolence |  |  |  |  |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x |  | x | 
| Abnormal vision |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |