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Diltiazem

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: C08DB01

Side effects

Options: Show MedDRA Preferred Terms,   display all 37 labels

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Edema of lower extremities postmarketing, 3.78% - 8.13% 3.33% x x x x x x x x
Headache 2.1% - 17% 2% - 13.8% x x x x x x x x x x x x x x x x x x x
Fatigue 4.8% x x x x
Oedema 1.9% - 14.6% 0% - 2% x x x x x x x x x x x x x x x x x x x x
Pain 0.99% - 6.33% 0% - 2.3% x x x x x
Dizziness 1.5% - 10.2% 0% - 7.02% x x x x x x x x x x x x x x x x x x x
Oedema peripheral 2% - 5% x
Sinus bradycardia 3% x x
Nasopharyngitis 2.94% x
Asthenia 0.6% - 6% 0% - 4% x x x x x x x x x x x x x x x x x x
Atrioventricular block first degree 1.8% - 3.3% 0% x x x x x x x x x x x x x
Bronchitis 0.633% - 4.08% 0% x x
Vasodilation postmarketing, 1% - 3.36% 1.75% x x x x x x x x
Cough 1.27% - 2.97% 0% - 2.3% x x x x x x
Influenza 0% - 2.31% 0% - 1.15% x
Myalgia postmarketing, 0% - 2.31% 0% x x x
Pharyngitis 1.44% - 6.25% 2% - 4.6% x x
Palpitations 1.2% - 2.08% 0% - 0.948% x x x x x x x x x x x x x x x x x x x
Rhinitis 1% - 9.57% 2% - 8.05% x x x x
Diarrhoea 1.34% - 2.08% 0% x x x x x x x x x x x x x x x x x x x
Sinusitis 1.98% - 2.94% 1.15% x
Vomiting 1.98% 0% x x x x x x x x x x x x x x x x x x x x
Bradycardia postmarketing, 1.44% - 6.03% 0% - 1.42% x x x x x x x x x x x x x x x x
Atrioventricular block 0% - 4.08% 0% x x x x x x x x x x x x x x x x x x x x
Nervousness 0% - 2.01% 0% x x x x x x x x x x x x x x x x x x
Paraesthesia 1% - 2% x x x x x x x x x x x x x x x x x x x
Tachycardia 1% - 2% x x x x x x x x x x x x x x x x x x
Arthralgia 1.44% 0% x
Cardiac fibrillation 1.44% 0% x
Flushing postmarketing, 1.4% - 3% x x x x x x x x x x x x x x x x
Nausea 1.27% - 5% 0% - 1.15% x x x x x x x x x x x x x x x x x x x
Constipation 1% - 3.63% 0.948% - 2.3% x x x x x x x x x x x x x x x x x x
Infection 0.6% - 6.25% 0% - 3.51% x x x x
Somnolence 1.27% x x x x x x x x x x x x x x x x x x x
Dyspepsia 0% - 6.12% 0% - 0.474% x x x x x x x x x x x x x x x x x
Gout 1.2% - 2.04% 0% x x x
Albuminuria 1.2% x x x x
Arrhythmia 1.2% x
Rash postmarketing, 0% - 2.04% 0% - 1.15% x x x x x x x x x x x x x x x x x x
Hyperglycaemia 1.2% x x x x x x x x x x x x x x x x x x
Crystalluria 1.2% x x x x
Conjunctivitis 0% - 2.04% 0% x
Erectile dysfunction 0% - 2.04% 0% x x x x x x x x x x x x x x x x x x x
Extrasystoles 0% - 2.04% 0% x x
Enlargement abdomen 0% - 2.04% 0% x
Sinus congestion 0.399% - 1.63% 0% x x
Anorexia 1% x x x x x x x x x x x x x x x x x x x
Dyspnoea 0.6% - 6.12% 0% x x x x x x x x x x x x x x x x x x
Hypersensitivity 1% x x x x x x x x x x x x
Polyuria 1% - 1.27% 0.948% x x x x x x x x x x x x x x x x x x
Dry mouth 1% x x x x x x x x x x x x x x x x x x x
Neck stiffness 1% x x x x x
Arthropathy 0.99% 0%
Tinnitus 0.99% 0% x x x x x x x x x x x x x x x x x x x
Insomnia 0.952% - 0.99% 0% - 0.474% x x x x x x x x x x x x x x x x x x
Hypotension 0.952% 0.474% x x x x x x x x x x x x x x x x x x x
Agranulocytosis postmarketing x
Alopecia postmarketing x x x x x x x x x x x x x x x x x x
Haemolytic anaemia postmarketing x x x x x x x x x x x x x x x x x x
Angioedema postmarketing x x x x x x x x x x x x x x x x
Dermatitis exfoliative postmarketing x x x x x x x x x x x x x x x x x x x
Toxic epidermal necrolysis postmarketing x x x x x x x x x x x x x x x x x x x
Erythema multiforme postmarketing x x x x x x x x x x x x x x x x x x
Body temperature increased postmarketing x x x x x x
Gingival hyperplasia postmarketing x x x x x x x x x x x x x x x x x x
Gynaecomastia postmarketing x x x x x x x
Block heart postmarketing x
Orthostatic hypotension postmarketing x x x x x x
Leukopenia postmarketing x x x x x x x x x x x x x x x x x x
Myocardial infarction postmarketing x x x x x x x x x x x x x x x x x x x
Purpura postmarketing x x x x x x x x x x x x x x x x x x
Retinal disorder postmarketing x x x x x x x x x x x x x x x x x x
Sinoatrial block postmarketing x x x x x
Stevens-Johnson syndrome postmarketing x x x x x x x x x x x x x x
Sweating postmarketing x x x x x x x
Thrombocytopenia postmarketing x x x x x x x x x x x x x x x x x x
Erythema postmarketing x x x x x x
Vasculitis postmarketing x x x x x
Rash pustular postmarketing x x x x x
Allergic cutaneous angiitis postmarketing
Bleeding time prolonged postmarketing x x x x x x x x x x x x x x x x x x
Stomach ache postmarketing x x x x x
Malaise postmarketing x x x x x x
Extrapyramidal symptoms postmarketing x x x x x x x x x x x x x x x x x x
Abnormal vision postmarketing x
Amblyopia x x x x x x x x x x x x x x x x x x x
Amnesia x x x x x x x x x x x x x x x x x x
Bundle branch block x x x x x x x x x x x x x x x x x
Bursitis x
Neck pain x
Chest pain x x
Colitis x
Cystitis x
Dermatitis x
Dermatitis contact x
Diplopia x
Dysgeusia x x x x x x x x x x x x x x x x x x x
Dysmenorrhoea x
Ear pain x
Ecchymosis x
Endophthalmitis x
Epistaxis x x x x x x x x x x x x x x x x x x x
Eructation x
Extrapyramidal disorder x x x x x
Eye disorder x
Eye haemorrhage x
Flatulence x
Vitreous floaters x
Cardiac flutter x
Gastrointestinal disorder x
Gastrointestinal haemorrhage x
Hallucination x x x x x x x x x x x x x x x x x x
Cardiac arrest x x x x x x x x x
Cardiac disorder x
Cardiac failure congestive x x x x x x x x x x x x x x x x x x
Hepatitis x x x x x
Calculus of kidney x
Lethargy x
Mediastinal disorder x
Cramp muscle x x x x x x x x x x x x x x x x
Hypertonia x
Myopathy x x x
Nasal congestion x x x x x x x x x x x x x x x x x x
Nervous system disorder x
Nevus x
Nocturia x x x x x x x x x x x x x x x x x x
Otitis media x
Pallor x
Petechiae x x x x x x x x x x x x x x x x x x
Phlebitis x
Prostatic disorder x
Pruritus x x x x x x x x x x x x x x x x x x x
Pyelonephritis x
Renal failure x
Sinus headache x
Gastric ulcer x
Swelling x x x
Syncope x x x x x x x x x x x x x x x x x x x
Thirst x x x x x x x x x x x x x x x x x x
Tooth disorder x
Tremor x x x x x x x x x x x x x x x x x x
Pollakiuria x
Urinary tract infection x
Urinary tract disorder x
Urticaria x x x x x x x x x x x x x
Vaginal inflammation x
Angiopathy x
Ventricular fibrillation x
Ventricular tachycardia x
Vertigo x x
Weight increased x x x x x x x x x x x x x x x x x x x
Ventricular arrhythmia x
Mood swings x x x x x
Dissociation x
Periorbital oedema x x x x x x x x x
Atrioventricular block complete x
Creatine phosphokinase increased x x x x x x x x x x x x x
Necrolysis epidermal x
Ventricular extrasystoles x x x x x x x x x x x x x x x x x x x
Skin hypertrophy x
Injection site reaction x
Accidental injury x
Myocardial ischaemia x
Bone pain x
Aspartate aminotransferase increased x x
Joint swelling x
Malnutrition x
Skin hyperpigmentation x x
Lightheadedness x x
Nodal rhythm x
Thinking abnormal x
Abnormal dreams x x x x x x x x x x x x x x x x x x
Eye irritation x x x x x x x x x x x x x x x x x x
Personality change x x x x x x x x x x x x x x x x x x
Left ventricular dysfunction x
Atrioventricular block second degree x
Drug-induced parkinsonism
Vision blurred x
Photosensitivity x x x x x x x x x x x x x x x x x x
Sinoatrial node dysfunction x
Neuropathy x
Respiratory distress x
Lymphadenopathy x
Rash generalised x x x x x x x x x x x x
Electrocardiogram ST segment elevation x
Sinus arrest x
Face oedema x
Feeling jittery x
Gait disturbance x x x x x x x x x x x x x x x x x x
Neck swelling x
Hyperuricaemia x x x x x x x x x x x x x x x x x x
Hypotension asymptomatic x
Acute liver damage x x x
Hypotension symptomatic x
Acute generalised exanthematous pustulosis x x
Peripheral swelling x
Gastrointestinal discomfort x
Lichenoid keratosis x x
Osteoarticular pain x x x x x x x x x x x x x x x x x x
Acute liver injury x x x
Leukocytoclastic vasculitis x x x x x x x x x x x x x x x x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

DILZEM / Dilzem, Film coated tablet

Side effects:18
Source:Medsafe

DILTIAZEM

Side effects:71
Source:FDA Structured Product Label

Diltiazem

Side effects:72
Source:FDA Structured Product Label

Diltiazem

Side effects:72
Source:FDA Structured Product Label

DILTIAZEM

Side effects:73
Source:FDA Structured Product Label

DILTIAZEM

Side effects:76
Source:FDA Structured Product Label

Diltiazem

Side effects:77
Source:FDA Structured Product Label

DILTIAZEM

Side effects:78
Source:FDA Structured Product Label

DILTIAZEM

Side effects:80
Source:FDA Structured Product Label

diltiazem hydrochloride / Cardizem LA

Side effects:81
Source:FDA

Diltiazem hydrochloride / Coras

Side effects:82
Source:medicines.org.au

Diltiazem

Side effects:84
Source:FDA Structured Product Label

Diltiazem hydrochloride / CARDIZEM CD

Side effects:84
Source:medicines.org.au

Diltiazem hydrochloride / CARDIZEM TABLETS

Side effects:84
Source:medicines.org.au

Diltiazem hydrochloride / VASOCARDOL CD

Side effects:84
Source:medicines.org.au

DILTIAZEM

Side effects:85
Source:FDA Structured Product Label

Diltiazem

Side effects:85
Source:FDA Structured Product Label

DILTIAZEM HYDROCHLORIDE / TIAZAC XC

Side effects:98
Source:Health Canada

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label