Options: Show MedDRA Preferred Terms, display all 47 labels
Side effect | Data for drug | Placebo | Labels | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | |||
Nausea | 9% - 30% | 7% - 11% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Headache | very common, 9% - 20% | 8% - 15% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Dry mouth | 3% - 18% | 3% - 6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Constipation | 2% - 15% | 3% - 4% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Dizziness | 6% - 17% | 5% - 7% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Fatigue | 2% - 16% | 5% - 8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Insomnia | 5% - 16% | 5% - 10% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Somnolence | 5% - 21% | 3% - 5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Diarrhoea | 7% - 13% | 5% - 8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Decreased appetite | 1% - 14% | 1% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Hyperhidrosis | 2% - 10% | 1% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Abdominal pain | common — 2% - 6% | 4% - 5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Neck pain | common | x | x | x | x | x | x | |||||||||||||||
Hypoglycaemia | infrequent, frequent | x | ||||||||||||||||||||
Nasopharyngitis | 4% - 9% | 4% - 5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Nervousness | common, frequent | x | x | x | x | x | x | x | x | x | ||||||||||||
Nightmare | uncommon, frequent | x | x | x | x | x | x | x | x | |||||||||||||
Skin ulcer | infrequent, frequent | x | ||||||||||||||||||||
Myalgia | common, 1% - 4% | 1% | x | x | x | x | x | x | x | |||||||||||||
Increased appetite | infrequent, frequent | x | ||||||||||||||||||||
Tension | infrequent, common | x | x | x | x | |||||||||||||||||
Upset stomach | common | x | x | x | x | x | x | |||||||||||||||
Initial insomnia | frequent | x | x | x | x | x | x | x | x | |||||||||||||
Middle insomnia | frequent | x | x | x | x | x | x | x | x | |||||||||||||
Feeling jittery | infrequent, common | x | x | x | x | x | x | x | ||||||||||||||
Asthenia | frequent, 2% - 8% | 1% | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Libido decreased | frequent, 1% - 6% | 0% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Cramp muscle | 4% - 5% | 3% | x | x | x | x | ||||||||||||||||
Upper respiratory tract infection | 3% - 7% | 3% - 6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Vomiting | 3% - 6% | 2% - 4% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Agitation | infrequent — 1% - 6% | 1% - 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Erectile dysfunction | 0% - 5% | 0% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Anorexia | 3% - 5% | 1% | x | x | x | x | x | x | x | x | x | |||||||||||
Anxiety | common — 3% | 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Back pain | 2% - 5% | 3% | x | x | x | x | x | x | ||||||||||||||
Cough | 2% - 6% | 2% - 4% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Seasonal allergy | 3% | 2% | x | |||||||||||||||||||
Influenza | 2% - 3% | 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Musculoskeletal pain | postmarketing — 3% - 5% | 3% - 4% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Tremor | 0% - 5% | 0% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Urinary tract infection | 3% | 3% | x | |||||||||||||||||||
Migraine | 3% | 3% | x | |||||||||||||||||||
Ejaculation delayed | frequent, 2% - 3% | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Vision blurred | postmarketing — 2% - 3% | 1% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Pharyngolaryngeal pain | 1% - 6% | 1% - 3% | x | x | x | x | x | |||||||||||||||
Pain | postmarketing, 4% | 4% | x | x | x | |||||||||||||||||
Dyspepsia | common — 2% - 5% | 1% - 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Body temperature increased | 1% - 3% | 1% | x | x | x | x | ||||||||||||||||
Orgasm abnormal | postmarketing — 2% - 4% | 0% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Palpitations | postmarketing — 2% | 1% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Paraesthesia | postmarketing — 1% - 4% | 2% - 4% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Penis disorder | 2% | 0% | x | |||||||||||||||||||
Muscle spasms | postmarketing — 2% - 4% | 2% - 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Weight decreased | postmarketing — 2% | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Yawning | postmarketing — 2% | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Viral diarrhoea | 2% | 2% | x | |||||||||||||||||||
Ejaculation disorder | uncommon — 2% - 4% | 0% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Blood pressure increased | uncommon, 2% | 1% | x | x | x | x | x | x | ||||||||||||||
Loose stools | 2% - 3% | 1% | x | x | x | x | ||||||||||||||||
Oropharyngeal pain | postmarketing — 2% | 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Pollakiuria | postmarketing — 1% - 5% | 2% | x | x | x | x | x | |||||||||||||||
Alopecia | infrequent | x | x | |||||||||||||||||||
Anaemia | infrequent | x | x | |||||||||||||||||||
Ataxia | infrequent | |||||||||||||||||||||
Atrial fibrillation | infrequent | x | x | |||||||||||||||||||
Colitis | rare, infrequent | x | x | |||||||||||||||||||
Conjunctivitis | infrequent | x | ||||||||||||||||||||
Dermatitis exfoliative | rare, infrequent | x | ||||||||||||||||||||
Diverticulitis | rare, infrequent | x | ||||||||||||||||||||
Eczema | infrequent | x | x | |||||||||||||||||||
Oedema | infrequent | x | ||||||||||||||||||||
Flushing | postmarketing — 2% - 3% | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Gingivitis | rare, infrequent | x | x | |||||||||||||||||||
Cardiac failure | rare, infrequent | x | ||||||||||||||||||||
Cardiac failure congestive | rare, infrequent | x | ||||||||||||||||||||
Hypercholesterolaemia | infrequent | x | ||||||||||||||||||||
Irritable bowel syndrome | infrequent | x | x | |||||||||||||||||||
Nephropathy | rare, infrequent | x | ||||||||||||||||||||
Leukopenia | infrequent | x | x | |||||||||||||||||||
Macular degeneration | rare, infrequent | x | ||||||||||||||||||||
Mydriasis | uncommon | x | x | x | ||||||||||||||||||
Oliguria | rare, infrequent | x | ||||||||||||||||||||
Phlebitis | rare, infrequent | x | x | |||||||||||||||||||
Prurigo | infrequent | |||||||||||||||||||||
Retinal detachment | rare, infrequent | x | ||||||||||||||||||||
Thrombocytopenia | postmarketing, infrequent | x | x | x | ||||||||||||||||||
Urinary incontinence | infrequent | x | x | |||||||||||||||||||
Urinary retention | postmarketing — uncommon | x | x | x | x | x | x | |||||||||||||||
Bundle branch block right | rare, infrequent | x | ||||||||||||||||||||
Photopsia | rare, infrequent | x | ||||||||||||||||||||
Oedema peripheral | infrequent | x | x | x | ||||||||||||||||||
Syndrome sicca | infrequent | |||||||||||||||||||||
Gamma-glutamyltransferase increased | uncommon | x | x | |||||||||||||||||||
Liver function test abnormal | uncommon | x | x | |||||||||||||||||||
Muscular weakness | rare, infrequent | x | ||||||||||||||||||||
Aspartate aminotransferase increased | postmarketing, uncommon | x | x | x | ||||||||||||||||||
Alanine aminotransferase increased | postmarketing, uncommon | x | x | x | ||||||||||||||||||
Urinary hesitation | infrequent — frequent | x | x | x | x | x | x | |||||||||||||||
Abdominal pain lower | infrequent | x | x | x | x | x | x | x | x | |||||||||||||
Pressure of speech | rare, infrequent | x | x | |||||||||||||||||||
Abnormal dreams | postmarketing — 2% - 3% | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Rash erythematous | infrequent | |||||||||||||||||||||
Blood creatinine increased | rare, infrequent | x | ||||||||||||||||||||
Hepatic enzyme increased | uncommon | x | x | x | ||||||||||||||||||
Blood pressure systolic increased | uncommon | x | x | |||||||||||||||||||
Blood pressure diastolic increased | uncommon | x | x | |||||||||||||||||||
Ejaculation failure | uncommon | x | x | x | x | x | x | x | x | |||||||||||||
Gastric irritation | infrequent | |||||||||||||||||||||
Lymphadenopathy | infrequent | x | x | |||||||||||||||||||
Coordination abnormal | infrequent | x | ||||||||||||||||||||
Influenza like illness | infrequent | x | ||||||||||||||||||||
Impaired gastric emptying | rare, infrequent | x | ||||||||||||||||||||
Face oedema | rare, infrequent | x | x | |||||||||||||||||||
Urine flow decreased | rare, infrequent | x | x | x | x | x | ||||||||||||||||
Maculopathy | rare, infrequent | x | ||||||||||||||||||||
White blood cell count increased | rare, infrequent | x | x | |||||||||||||||||||
Oropharyngeal swelling | infrequent | |||||||||||||||||||||
Oesophageal stenosis acquired | infrequent | x | ||||||||||||||||||||
Hyperkeratosis | rare, infrequent | x | ||||||||||||||||||||
Hypersomnia | infrequent, frequent | x | x | x | x | x | ||||||||||||||||
Sluggishness | rare, infrequent | x | x | |||||||||||||||||||
Musculoskeletal stiffness | uncommon | x | x | |||||||||||||||||||
Blood in stool | infrequent | x | ||||||||||||||||||||
Coronary artery disease | infrequent | x | ||||||||||||||||||||
Hepatic steatosis | rare, infrequent | x | ||||||||||||||||||||
Loss of libido | infrequent | x | x | x | x | x | x | |||||||||||||||
Dysphagia | postmarketing, infrequent | x | x | x | x | |||||||||||||||||
Hypertriglyceridaemia | rare, infrequent | x | ||||||||||||||||||||
Aggression | very rare, postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Anaphylactic shock | very rare, postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Anger | very rare, postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Angioedema | very rare, postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Mental disorder | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Breast disorder | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Bruxism | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Infection | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Confusional state | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Connective tissue disorder | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Dehydration | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Dermatitis contact | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Diplopia | postmarketing, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Dysarthria | postmarketing — infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Dysgeusia | postmarketing — 3% | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Dyskinesia | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Dysuria | postmarketing — frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Ear pain | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Ecchymosis | postmarketing — infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Endocrine disorder | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Eructation | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Erythema multiforme | postmarketing | x | x | x | x | x | ||||||||||||||||
Oesophageal stenosis | rare | x | ||||||||||||||||||||
Rash | postmarketing — 4% | 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Extrapyramidal disorder | very rare, postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Eye disorder | postmarketing, 3% | 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Flatulence | postmarketing — frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Gastritis | postmarketing — frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Gastroenteritis | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Gastrointestinal disorder | postmarketing, 14% - 30% | 9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Gastrointestinal haemorrhage | postmarketing — uncommon | x | x | x | x | x | x | x | ||||||||||||||
Glaucoma | very rare — infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Angle closure glaucoma | postmarketing | x | x | |||||||||||||||||||
Breath odour | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Hallucination | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Cardiac disorder | postmarketing, 2% | 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Haematochezia | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Blood disorder | postmarketing | x | x | x | ||||||||||||||||||
Haemorrhage | very rare, postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Hyperglycaemia | very rare, postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Hyperlipidaemia | postmarketing, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Hyperprolactinaemia | very rare, postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Hypersensitivity | very rare, postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Hypertensive crisis | very rare — infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Hypoaesthesia | postmarketing — frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Orthostatic hypotension | very rare — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Hypothyroidism | postmarketing — infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Immune system disorder | postmarketing | x | x | x | x | x | ||||||||||||||||
Irritability | postmarketing — frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Laryngitis | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Lethargy | postmarketing — frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Mediastinal disorder | postmarketing, 2% | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Melaena | postmarketing — infrequent | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Menstrual disorder | postmarketing, rare | x | x | x | x | x | ||||||||||||||||
Myocardial infarction | postmarketing, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Myoclonus | postmarketing — infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Nervous system disorder | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Night sweats | postmarketing — frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Nocturia | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Polyuria | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Pruritus | postmarketing — 3% | 2% | x | x | x | x | x | x | x | x | x | |||||||||||
Restless legs syndrome | very rare, postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Convulsion | very rare, postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Stevens-Johnson syndrome | very rare, postmarketing | x | x | x | x | x | x | x | x | |||||||||||||
Gastric ulcer | postmarketing — infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Stomatitis | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Aphthous stomatitis | rare | x | ||||||||||||||||||||
Suicide attempt | postmarketing, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Tachycardia | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Testicular pain | postmarketing, infrequent | x | x | |||||||||||||||||||
Thirst | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Tinnitus | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Trismus | very rare, postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Erythema | postmarketing, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Urinary tract disorder | postmarketing | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Urticaria | very rare, postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Angiopathy | postmarketing, 2% - 3% | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Vertigo | postmarketing — frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Weight increased | postmarketing — 2% | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Chills | postmarketing — frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Micturition urgency | postmarketing, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Apathy | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Mood swings | postmarketing, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Malnutrition | postmarketing, 7% - 9% | 1% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Photosensitivity reaction | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Unspecified disorder of skin and subcutaneous tissue | postmarketing, 6% | 1% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Malaise | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Muscle twitching | postmarketing — frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Cold sweat | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Disorientation | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Disturbance in attention | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Anorgasmia | postmarketing, frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Galactorrhoea | very rare, postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Pharyngeal oedema | rare | x | ||||||||||||||||||||
Throat tightness | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Menopausal symptoms | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Dyslipidaemia | postmarketing — infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Hepatobiliary disease | postmarketing | x | x | x | x | x | ||||||||||||||||
Peripheral coldness | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Urine odour abnormal | postmarketing — infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Blood bilirubin increased | very rare — uncommon | x | x | x | ||||||||||||||||||
Dry eye | postmarketing — uncommon | x | x | x | x | x | ||||||||||||||||
Mania | very rare — infrequent | x | x | x | x | x | x | |||||||||||||||
Increased tendency to bruise | postmarketing, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Rigors | postmarketing — frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Arrhythmia supraventricular | very rare, postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Visual disturbance | postmarketing, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Sexual dysfunction | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Gait disturbance | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Blood cholesterol increased | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Hot flush | postmarketing — 2% - 3% | 1% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Infestation NOS | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Ear and labyrinth disorders | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Sleep disorder | postmarketing — 3% | 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Completed suicide | postmarketing — infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Muscle tightness | postmarketing — frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Poor quality sleep | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Feeling abnormal | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Feeling hot | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Visual impairment | postmarketing — uncommon | x | x | x | x | x | ||||||||||||||||
Hepatitis | very rare, postmarketing | x | x | x | x | |||||||||||||||||
Hyponatraemia | very rare, postmarketing | x | x | x | x | |||||||||||||||||
Inappropriate antidiuretic hormone secretion | very rare, postmarketing | x | x | x | x | |||||||||||||||||
Jaundice | very rare, postmarketing | x | x | x | x | |||||||||||||||||
Syncope | very rare, postmarketing | x | x | x | x | |||||||||||||||||
Phosphatase alkaline increased | very rare, postmarketing | x | x | x | ||||||||||||||||||
Diabetic | very rare | x | ||||||||||||||||||||
Serotonin syndrome | very rare, postmarketing | x | x | x | x | |||||||||||||||||
Arrhythmia | x | |||||||||||||||||||||
Arthralgia | x | x | x | |||||||||||||||||||
Chest pain | x | |||||||||||||||||||||
Contusion | x | |||||||||||||||||||||
Diabetes mellitus | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Electric shock | ||||||||||||||||||||||
Epistaxis | x | |||||||||||||||||||||
Hypertension | x | |||||||||||||||||||||
Low back pain | x | x | x | x | x | |||||||||||||||||
Osteoarthritis | x | x | x | x | x | |||||||||||||||||
Pain in extremity | x | |||||||||||||||||||||
Pancreatitis | x | x | ||||||||||||||||||||
Pharyngitis | x | x | x | |||||||||||||||||||
Rhabdomyolysis | x | x | ||||||||||||||||||||
Sleep disturbance | x | |||||||||||||||||||||
Supraventricular tachycardia | x | |||||||||||||||||||||
Essential hypertension | ||||||||||||||||||||||
Hepatic failure | x | x | x | x | ||||||||||||||||||
Ventricular arrhythmia | x | x | ||||||||||||||||||||
Withdrawal symptom | x | |||||||||||||||||||||
Creatine phosphokinase increased | x | |||||||||||||||||||||
Secondary hypertension | ||||||||||||||||||||||
Liver injury | x | |||||||||||||||||||||
Systolic hypertension | ||||||||||||||||||||||
Cardiac fibrillation | ||||||||||||||||||||||
Abdominal discomfort | x | x | x | x | x | x | x | |||||||||||||||
Abdominal pain upper | x | x | x | x | x | x | x | x | ||||||||||||||
Abdominal tenderness | x | x | x | x | x | x | x | |||||||||||||||
Extrapyramidal symptoms | ||||||||||||||||||||||
Diastolic hypertension | ||||||||||||||||||||||
Hepatotoxicity | x | |||||||||||||||||||||
Glycosylated haemoglobin increased | x | |||||||||||||||||||||
Blood pressure diastolic decreased | x | |||||||||||||||||||||
Akathisia | x | |||||||||||||||||||||
Suicidal ideation | x | |||||||||||||||||||||
Paraesthesia oral | x | |||||||||||||||||||||
Terminal insomnia | x | x | x | x | x | x | x | |||||||||||||||
Orthostatic hypertension | ||||||||||||||||||||||
Gastrointestinal pain | x | x | x | x | x | x | x | |||||||||||||||
Sweating increased | x | x | x | x | ||||||||||||||||||
Hemorrhage abnormal | x | x | ||||||||||||||||||||
Blood and lymphatic system disorders | x | x | ||||||||||||||||||||
Blood creatine phosphokinase increased | ||||||||||||||||||||||
Blood potassium increased | ||||||||||||||||||||||
Fasting blood glucose increased | x | |||||||||||||||||||||
Renal impairment | x | x | ||||||||||||||||||||
Hypoaesthesia facial | x | x | x | |||||||||||||||||||
Suicidal behaviour | ||||||||||||||||||||||
Acute liver injury | x | |||||||||||||||||||||
Genital hypoaesthesia | ||||||||||||||||||||||
Labile hypertension |
Information about indications was extracted from the indications and usage sections of the labels.
standard – alternative
100% | ||
75% | ||
50% | ||
10% | ||
frequent (1% to 100%) | ||
infrequent (0.1% to 1%) | ||
rare (<0.1%) | ||
postmarketing | ||
0% | ||
no frequency information | ||
not found on label |