Options: Show MedDRA Preferred Terms, display all 26 labels
Side effect | Data for drug | Placebo | Labels | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | |||
Neoplasm malignant | 79% - 91.2% | x | x | x | ||||||||||||||||||
Haemoglobin decreased | 0.5% - 80.3% | 0% - 27% | x | x | ||||||||||||||||||
Lethargy | 11.7% - 74.9% | x | ||||||||||||||||||||
Oedema peripheral | 0.3% - 40.9% | 0% - 14.8% | x | x | x | x | ||||||||||||||||
Fatigue | very common, 0% - 74.9% | 1.2% - 40.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Hypoproteinaemia | 0% - 31.8% | x | x | |||||||||||||||||||
Skin exfoliation | 7.6% - 49.8% | x | ||||||||||||||||||||
Neutrophil count decreased | 3.3% - 33.3% | 0.9% - 6.1% | x | x | ||||||||||||||||||
Abdominal pain | very common, 0% - 57.2% | 1.4% - 22.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Dermatitis | very common, 1.5% - 38.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Diarrhoea | very common, 0.464% - 70% | 1.4% - 29.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Eczema | very common | x | x | x | x | |||||||||||||||||
Rash | very common, 0% - 53% | 0% - 12.8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Headache | very common, 0% - 43.3% | 0% - 20.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Musculoskeletal pain | very common, 0% - 49% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Nausea | very common, 0.4% - 74% | 1.2% - 27.8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Muscle spasms | very common, 0% - 49% | 0% - 3.3% | x | x | x | x | x | |||||||||||||||
Vomiting | very common, 0.5% - 58% | 0.6% - 13.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Periorbital oedema | very common, 0.5% - 74.2% | 0% - 14.5% | x | x | x | x | x | x | x | |||||||||||||
Bone pain | very common, 1.6% - 15.6% | x | x | x | x | x | x | |||||||||||||||
White blood cell count decreased | 0.6% - 47% | 0.3% - 4.3% | x | x | ||||||||||||||||||
Pain | 0.7% - 45.5% | x | x | x | ||||||||||||||||||
Depression | uncommon, 0% - 35.8% | 0.6% - 6.4% | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Hypoalbuminaemia | 0% - 21.2% | x | x | x | ||||||||||||||||||
Skin toxicity | 5.7% - 20.1% | x | ||||||||||||||||||||
Cramp muscle | very common, 0% - 62% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Arthralgia | very common, 0% - 40% | 0.3% - 14.5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Dyspepsia | very common, 0% - 27% | 0% - 13% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Oedema | very common, 0% - 86.1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Myalgia | very common, 0% - 38.8% | 0.3% - 11.6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Platelet count decreased | 0% - 14.1% | 0% - 3.5% | x | x | ||||||||||||||||||
Ascites | uncommon, 3% - 15% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Body temperature increased | common, 0% - 42.6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Pleural effusion | uncommon, 0% - 15% | x | x | x | x | x | x | x | x | x | ||||||||||||
Agranulocytosis | 3.1% - 16.1% | x | ||||||||||||||||||||
Lightheadedness | 2.8% - 11% | x | ||||||||||||||||||||
Pharyngeal mucositis | 4.3% - 10% | x | ||||||||||||||||||||
Dyspnoea | common, 0.5% - 21% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Pneumonia | uncommon, 0.155% - 13% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Fluid retention | very common, 0% - 81% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Back pain | 0% - 26% | 0% - 8.1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Sweating | 2.8% - 12.7% | x | ||||||||||||||||||||
Heartburn | 0.5% - 11.5% | x | ||||||||||||||||||||
Abdominal distension | common, 0% - 19.2% | 0.3% - 6.4% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Alopecia | common, 0% - 22.3% | 0% - 6.7% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Anorexia | common, 0% - 35.8% | 0% - 8.7% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Asthenia | common, 0% - 74.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Conjunctivitis | common, 0% - 7.6% | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Constipation | common, 0% - 16% | 0.3% - 17.7% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Cough | common, 0% - 27% | 0% - 11.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Dizziness | common, 0% - 24.4% | 0.3% - 10.7% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Epistaxis | common, 0% - 13% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Flatulence | common, 0% - 34% | 0% - 9.6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Gastrooesophageal reflux disease | common | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Haemorrhage | postmarketing — 0% - 53% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Hypoaesthesia | common | x | x | x | x | x | ||||||||||||||||
Night sweats | common, 0.2% - 17% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Paraesthesia | common, 0% - 12.1% | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Pruritus | common, 0% - 25.8% | 0% - 7.8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Erythema | common | x | x | x | x | x | ||||||||||||||||
Weight increased | very common, 0% - 32% | 0% - 11.6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Dry mouth | common, 0% - 10.9% | x | x | x | x | x | x | |||||||||||||||
Chills | common, 3% - 11% | x | x | x | x | x | ||||||||||||||||
Mouth ulceration | uncommon, common | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Generalised oedema | common | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Dry skin | common, 0% - 6.7% | 0% - 5.2% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Joint swelling | common | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Lacrimation increased | common, 0% - 18% | 0% - 3.8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Eyelid oedema | common | x | x | x | x | x | ||||||||||||||||
Vision blurred | common, 0% - 11.1% | 0% - 2.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Rigors | common, 0% - 34% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Face oedema | common, 0.3% - 6.8% | 0% - 1.2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Febrile neutropenia | common | x | x | x | x | x | ||||||||||||||||
Insomnia | common, 0% - 19% | 0% - 7.2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Loose stools | 0% - 12% | x | x | x | x | x | x | |||||||||||||||
Neutropenia | postmarketing — 0% - 100% | x | x | x | x | x | x | x | x | |||||||||||||
Anaemia | postmarketing — 0% - 42% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Influenza like illness | 0% - 15.9% | x | ||||||||||||||||||||
Hypokalaemia | uncommon, 0.2% - 33.7% | 0.6% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Throat sore | 0% - 11% | x | x | x | x | x | ||||||||||||||||
Pain in extremity | 0.3% - 7.4% | 0% - 7.2% | x | |||||||||||||||||||
Leukopenia | 0.3% - 19.6% | 0% - 2.6% | x | x | x | |||||||||||||||||
Abdominal pain upper | 0.3% - 6.2% | 0% - 6.4% | x | |||||||||||||||||||
Weight decreased | infrequent — 0% - 17.3% | 0% - 5.2% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Dysgeusia | common, 0% - 15% | 0% - 2.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Upper respiratory tract infection | uncommon — 0% - 21.2% | 0% - 3.5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Hypocalcaemia | 0.3% - 5.6% | 0% - 1.7% | x | x | ||||||||||||||||||
Hypoxia | 0.309% - 8.7% | x | ||||||||||||||||||||
Sinusitis | uncommon, 0.2% - 11.4% | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Aspartate aminotransferase increased | 0% - 37.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Stomatitis | uncommon, 0.6% - 16.3% | 0% - 1.7% | x | x | x | x | x | |||||||||||||||
Mucosal inflammation | 0% - 10.3% | x | ||||||||||||||||||||
Alanine aminotransferase increased | 0% - 34.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Photosensitivity reaction | infrequent — 0% - 7.1% | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Chest pain | uncommon, 0.4% - 11% | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Infection | postmarketing — 0% - 53.3% | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Gastrointestinal haemorrhage | uncommon, 0.2% - 8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Petechiae | uncommon, 0% - 10% | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Tumour haemorrhage | postmarketing — 1% - 4% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Ecchymosis | uncommon, 0% - 11% | x | x | x | x | x | x | x | x | x | x | |||||||||||
Anxiety | infrequent — 0% - 12% | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Nasopharyngitis | uncommon, 0% - 30.5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Influenza | uncommon, 0% - 13.8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Blepharitis | uncommon | x | x | x | x | x | ||||||||||||||||
Cellulitis | uncommon | x | x | x | x | x | ||||||||||||||||
Cheilitis | uncommon | x | x | x | x | x | ||||||||||||||||
Conjunctival haemorrhage | infrequent, common | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Contusion | uncommon | x | x | x | x | x | x | x | x | x | ||||||||||||
Libido decreased | uncommon | x | x | x | x | x | ||||||||||||||||
Dysphagia | uncommon | x | x | x | x | x | ||||||||||||||||
Dehydration | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Dermatitis exfoliative | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Eosinophilia | postmarketing, uncommon | x | x | x | x | x | ||||||||||||||||
Eructation | uncommon | x | x | x | x | |||||||||||||||||
Oesophagitis | uncommon | x | x | x | x | x | ||||||||||||||||
Flushing | infrequent, common | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Folliculitis | uncommon | x | x | x | x | x | ||||||||||||||||
Gastritis | infrequent, common | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Gastroenteritis | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Gout | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Gynaecomastia | uncommon | x | x | x | x | x | ||||||||||||||||
Cardiac failure | infrequent | x | x | x | x | x | x | x | x | |||||||||||||
Cardiac failure congestive | uncommon | x | x | x | x | |||||||||||||||||
Haematemesis | uncommon | x | x | x | x | x | ||||||||||||||||
Haematoma | uncommon | x | x | x | x | x | ||||||||||||||||
Subdural haematoma | uncommon | x | x | x | x | x | ||||||||||||||||
Haematuria | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Hepatitis | uncommon | x | x | x | x | x | x | x | x | x | ||||||||||||
Herpes simplex | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Herpes zoster | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Hyperbilirubinaemia | uncommon | x | x | x | x | |||||||||||||||||
Hypercalcaemia | uncommon | x | x | x | x | x | ||||||||||||||||
Hyperglycaemia | uncommon, 0.6% - 9.8% | 1.7% - 11.3% | x | x | x | x | x | x | ||||||||||||||
Hypertension | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Hypotension | infrequent — 0.927% - 10.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Hypotrichosis | uncommon | x | x | x | x | x | ||||||||||||||||
Jaundice | uncommon | x | x | x | x | x | x | |||||||||||||||
Renal failure acute | uncommon | x | x | x | x | x | ||||||||||||||||
Lymphopenia | uncommon, 0.7% - 10.1% | x | x | x | x | x | x | x | ||||||||||||||
Melaena | uncommon | x | x | x | x | x | ||||||||||||||||
Menorrhagia | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Nail disorder | infrequent | x | x | x | x | x | x | x | x | x | ||||||||||||
Palpitations | uncommon, 0% - 5.2% | x | x | x | x | x | ||||||||||||||||
Pancreatitis | rare, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Pancytopenia | infrequent, common | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Neuropathy peripheral | infrequent — 0% - 5.9% | 0% - 6.4% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Pharyngitis | uncommon, 0% - 15% | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Psoriasis | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Pulmonary oedema | uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Purpura | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Renal failure | infrequent, uncommon | x | x | x | x | |||||||||||||||||
Restless legs syndrome | uncommon | x | x | x | x | x | ||||||||||||||||
Sciatica | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Pigmentation skin | infrequent | x | x | x | x | x | x | x | x | |||||||||||||
Gastric ulcer | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Syncope | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Tachycardia | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Tinnitus | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Tremor | uncommon | x | x | x | x | x | ||||||||||||||||
Pollakiuria | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Urinary tract infection | uncommon | x | x | x | x | x | ||||||||||||||||
Urticaria | uncommon | x | x | x | x | x | ||||||||||||||||
Vertigo | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Rash pustular | uncommon | x | x | x | x | x | ||||||||||||||||
Hypophosphataemia | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Migraine | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Creatine phosphokinase increased | infrequent | x | x | x | x | x | x | x | x | x | ||||||||||||
Scrotal oedema | uncommon | x | x | x | x | x | ||||||||||||||||
Lactic dehydrogenase activity increased | infrequent | x | x | x | x | x | x | x | x | x | ||||||||||||
Bone marrow depression | uncommon | x | x | x | x | x | ||||||||||||||||
Eye pain | uncommon | x | x | x | x | x | ||||||||||||||||
Menstruation irregular | uncommon | x | x | x | x | x | ||||||||||||||||
Skin hyperpigmentation | uncommon | x | x | x | x | x | ||||||||||||||||
Leukoderma | uncommon | x | x | x | x | x | ||||||||||||||||
Muscle stiffness | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Malaise | uncommon, 11.7% - 74.9% | x | x | x | x | x | ||||||||||||||||
Increased appetite | uncommon | x | x | x | x | x | ||||||||||||||||
Decreased appetite | uncommon, 0% - 10.1% | x | x | x | x | x | ||||||||||||||||
Memory impairment | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Eye irritation | uncommon | x | x | x | x | x | ||||||||||||||||
Blood creatinine increased | uncommon — 0% - 44.4% | 0.3% - 5.8% | x | x | x | x | x | |||||||||||||||
Bullous eruption | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Nipple pain | uncommon | x | x | x | x | x | ||||||||||||||||
Erectile dysfunction | uncommon | x | x | x | x | x | ||||||||||||||||
Sepsis | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Peripheral coldness | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Dry eye | infrequent, common | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Increased tendency to bruise | uncommon | x | x | x | x | x | ||||||||||||||||
Orbital oedema | uncommon | x | x | x | x | x | ||||||||||||||||
Lymphadenopathy | uncommon | x | x | x | x | x | ||||||||||||||||
Onychoclasis | uncommon | x | x | x | x | x | ||||||||||||||||
Sexual dysfunction | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Renal pain | uncommon | x | x | x | x | x | ||||||||||||||||
Sweating increased | uncommon, 0.2% - 14.8% | x | x | x | x | x | x | |||||||||||||||
Hyperuricaemia | uncommon | x | x | x | x | x | ||||||||||||||||
Scleral haemorrhage | uncommon | x | x | x | x | x | ||||||||||||||||
Thrombocytosis | uncommon | x | x | x | x | x | ||||||||||||||||
Blood alkaline phosphatase increased | uncommon, 0% - 16.7% | 0% - 7.5% | x | x | x | x | x | |||||||||||||||
Blood creatine phosphokinase increased | uncommon | x | x | x | x | |||||||||||||||||
Blood lactate dehydrogenase increased | uncommon, 0% - 60.1% | x | x | x | x | x | ||||||||||||||||
Pharyngolaryngeal pain | uncommon, 0% - 18.1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Hearing impaired | uncommon | x | x | x | x | x | ||||||||||||||||
Breast enlargement | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Somnolence | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Cerebral haemorrhage | uncommon, 0% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Thrombocytopenia | postmarketing — 0% - 97.8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Blood bilirubin increased | 0% - 13.1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Skin disorder | 0% - 4.35% | x | ||||||||||||||||||||
Retinal haemorrhage | rare, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Macular oedema | rare, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Phosphatase alkaline increased | 0% - 5.5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Anaphylactic shock | very rare — rare | x | x | x | x | x | x | |||||||||||||||
Aplastic anaemia | rare | x | x | x | x | x | x | x | x | x | ||||||||||||
Haemolytic anaemia | rare | x | x | x | x | x | ||||||||||||||||
Angina pectoris | rare | x | x | x | x | x | ||||||||||||||||
Angioedema | rare | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Arrhythmia | rare | x | x | x | x | x | ||||||||||||||||
Arthritis | rare | x | x | x | x | x | ||||||||||||||||
Atrial fibrillation | rare | x | x | x | x | x | ||||||||||||||||
Blast cell crisis | postmarketing | x | x | |||||||||||||||||||
Edema cerebral | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Cardiac tamponade | postmarketing, rare | x | x | x | x | x | ||||||||||||||||
Pleuritic pain | rare | x | x | x | x | x | ||||||||||||||||
Colitis | rare | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Confusional state | rare | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Connective tissue disorder | postmarketing | x | x | x | x | x | ||||||||||||||||
Cyst | postmarketing | x | x | x | x | |||||||||||||||||
Cytopenia | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Drug eruption | postmarketing | x | ||||||||||||||||||||
Diverticulitis | postmarketing, rare | x | x | x | x | x | x | x | x | x | ||||||||||||
Embolism | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Toxic epidermal necrolysis | very rare, postmarketing | x | x | x | x | x | ||||||||||||||||
Erythema multiforme | rare | x | x | x | x | x | ||||||||||||||||
Eye disorder | postmarketing | x | x | x | x | x | ||||||||||||||||
Gastrointestinal disorder | postmarketing | x | x | x | x | x | ||||||||||||||||
Glaucoma | rare | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Cardiac arrest | rare | x | x | x | x | x | ||||||||||||||||
Cardiac disorder | postmarketing, rare | x | x | x | x | x | ||||||||||||||||
Hyperkalaemia | rare | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Hypersensitivity | rare | x | x | x | x | x | x | x | x | x | ||||||||||||
Pulmonary hypertension | rare | x | x | x | x | x | ||||||||||||||||
Hyponatraemia | rare, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Immune system disorder | postmarketing | x | x | |||||||||||||||||||
Inflammatory bowel disease | rare | x | x | x | x | x | ||||||||||||||||
Intestinal obstruction | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Chronic phase chronic myeloid leukemia | postmarketing | x | x | |||||||||||||||||||
Lichen planus | postmarketing, rare | x | x | x | x | x | ||||||||||||||||
Mediastinal disorder | postmarketing | x | x | x | x | x | ||||||||||||||||
Myopathy | postmarketing, rare | x | x | x | x | x | ||||||||||||||||
Fungal infection | rare | x | x | x | x | x | ||||||||||||||||
Myocardial infarction | rare | x | x | x | x | x | ||||||||||||||||
Necrosis | postmarketing | x | x | |||||||||||||||||||
Necrosis ischaemic | postmarketing, rare | x | x | x | x | x | x | x | x | x | ||||||||||||
Neoplasm | postmarketing, 5% - 20.8% | x | x | x | x | x | x | |||||||||||||||
Nervous system disorder | postmarketing | x | x | x | x | x | ||||||||||||||||
Optic neuritis | rare | x | x | x | x | x | ||||||||||||||||
Osteonecrosis | postmarketing, rare | x | x | x | x | x | x | x | ||||||||||||||
Papilloedema | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Pericardial effusion | rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Pericarditis | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Polyp | postmarketing | x | x | x | x | |||||||||||||||||
Pulmonary fibrosis | rare | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Rhabdomyolysis | postmarketing, rare | x | x | x | x | x | ||||||||||||||||
Convulsion | rare | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Stevens-Johnson syndrome | rare | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Thrombosis | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Tumour lysis syndrome | rare | x | x | x | x | |||||||||||||||||
Angiopathy | postmarketing | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Vitreous haemorrhage | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Acute febrile neutrophilic dermatosis | rare | x | x | x | x | x | x | x | x | x | ||||||||||||
Hepatic failure | postmarketing — 4% - 17.3% | x | x | x | x | x | x | x | x | x | ||||||||||||
Cataract | rare | x | x | x | x | x | ||||||||||||||||
Hepatitis cholestatic | postmarketing | x | x | x | ||||||||||||||||||
Allergic cutaneous angiitis | rare | x | x | x | x | x | ||||||||||||||||
Gastrointestinal perforation | postmarketing, uncommon | x | x | x | x | x | x | x | x | |||||||||||||
Growth retardation | postmarketing | x | x | x | x | x | ||||||||||||||||
Pulmonary haemorrhage | rare | x | x | x | x | x | ||||||||||||||||
Hypomagnesaemia | rare | x | x | x | x | x | ||||||||||||||||
Intracranial pressure increased | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Muscular weakness | rare | x | x | x | x | x | ||||||||||||||||
Hepatic necrosis | rare | x | x | x | x | x | ||||||||||||||||
Unspecified disorder of skin and subcutaneous tissue | postmarketing | x | x | x | x | x | ||||||||||||||||
Interstitial pneumonia | rare | x | x | x | x | x | x | x | x | x | ||||||||||||
Interstitial lung disease | postmarketing, uncommon | x | x | x | x | x | ||||||||||||||||
Rash vesicular | rare | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Nail discolouration | rare | x | x | x | x | x | ||||||||||||||||
Acute respiratory failure | postmarketing, uncommon | x | x | x | x | x | ||||||||||||||||
Tumour necrosis | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Haemorrhagic ovarian cyst | very rare — rare | x | x | x | x | x | ||||||||||||||||
Blood amylase increased | rare | x | x | x | x | x | ||||||||||||||||
Acute generalised exanthematous pustulosis | rare | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Ileus | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Lichenoid keratosis | postmarketing, rare | x | x | x | x | x | ||||||||||||||||
Mental disorder | x | x | x | x | ||||||||||||||||||
Bladder cancer | x | |||||||||||||||||||||
Bone disorder | x | |||||||||||||||||||||
Breast disorder | x | x | x | x | ||||||||||||||||||
Hypoglycaemia | x | |||||||||||||||||||||
Mastocytosis | x | |||||||||||||||||||||
Musculoskeletal disorder | x | x | x | |||||||||||||||||||
Rhinitis | x | x | x | |||||||||||||||||||
Ulcer | x | x | ||||||||||||||||||||
Urinary tract disorder | x | x | x | x | ||||||||||||||||||
Vasculitis | ||||||||||||||||||||||
Lower respiratory tract infection | x | x | x | |||||||||||||||||||
Creatinine increased | 0% - 8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Malnutrition | x | x | x | x | ||||||||||||||||||
Acute hepatic failure | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Dyspnoea exertional | x | x | x | |||||||||||||||||||
Digestion impaired | x | x | ||||||||||||||||||||
Hepatotoxicity | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Gastrointestinal obstruction | x | x | ||||||||||||||||||||
Gastrointestinal stromal tumour | x | x | ||||||||||||||||||||
Edema of lower extremities | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Hepatobiliary disease | x | x | x | x | x | |||||||||||||||||
Chronic eosinophilic leukaemia | x | x | ||||||||||||||||||||
Prostate cancer | x | |||||||||||||||||||||
Haematological malignancy | x | x | x | |||||||||||||||||||
Drug interaction | x | |||||||||||||||||||||
Skin carcinoma | x | |||||||||||||||||||||
Renal cancer | x | |||||||||||||||||||||
Eye oedema | x | x | x | |||||||||||||||||||
Infestation NOS | x | x | x | x | ||||||||||||||||||
Blood and lymphatic system disorders | x | x | x | x | ||||||||||||||||||
Ear and labyrinth disorders | x | x | x | x | ||||||||||||||||||
Myelosuppression | x | x | x | x | ||||||||||||||||||
Oedema aggravated | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Post procedural haemorrhage | x | x | x | x | ||||||||||||||||||
Blood in stool | x | x | x | x |
Information about indications was extracted from the indications and usage sections of the labels.
Indication | Labels | |||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acute lymphocytic leukaemia | x | x | x | x | x | x | x | |||||||||||||||
Aggressive systemic mastocytosis | x | x | x | |||||||||||||||||||
Blast cell crisis | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Cardiac failure congestive | x | x | x | |||||||||||||||||||
Chronic eosinophilic leukaemia | x | x | x | x | x | x | ||||||||||||||||
Chronic myeloid leukaemia | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Chronic phase chronic myeloid leukemia | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Dermatofibrosarcoma protuberans | x | x | x | x | x | x | x | |||||||||||||||
Gastrointestinal stromal tumour | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Hypereosinophilic syndrome | x | x | x | x | x | x | x | |||||||||||||||
Infection | x | x | x | |||||||||||||||||||
Leukaemia | x | |||||||||||||||||||||
Neutropenia | x | x | x | |||||||||||||||||||
Philadelphia chromosome positive | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Pleural effusion | x | x | x | |||||||||||||||||||
Renal failure | x | x | x | |||||||||||||||||||
Systemic mastocytosis | x |
standard – alternative
100% | ||
75% | ||
50% | ||
10% | ||
frequent (1% to 100%) | ||
infrequent (0.1% to 1%) | ||
rare (<0.1%) | ||
postmarketing | ||
0% | ||
no frequency information | ||
not found on label |